THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: January 7, 2009 07:00 AM Wednesday; Rod Welch

Millie sunitinib #48 treatment IBC 5th relapse.

1...Summary/Objective
2...Sunitinib Metronomic Treatment Loading Dose Clinical Study UCSF
3...Sunitinib Cyclophosmaide Methotrexate Patient History
4...Side Effects Sunitinib Study with Cyclophosphamide Methotrexate
5...Exercise Hiking Maintain Fitness Strengthen Immune System
6...Case Study on Pateint History Exercising


..............
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CONTACTS 

SUBJECTS
Default Null Subject Account for Blank Record

0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS H6 0000. ref SDS H5 0000.
040502 -
040503 -
040504 -
040505 -
040507 -  ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Sunitinib Metronomic Treatment Loading Dose Clinical Study UCSF
040902 -
040903 - Follow up ref SDS H6 505G, ref SDS H5 505G.
040904 -
040905 - Background pausing treatment on 081219 for a week for Millie's blood
040906 - counts to recover, and resuming on 081226 with sunitinib and
040907 - cyclophosphamide. ref SDS G2 505G
040909 -  ..
040910 - Today, IBC rash and nodules in breastbone possibly improving after a
040911 - few days getting worse, reported on 090105. ref SDS H5 124N
040913 -  ..
040914 - CT test report for scans on 081230 indicates declining cancer with
040915 - nodes in right axillary stable, and significant decline of lymph
040916 - adenopathy in left and right supraclavicular.
040918 -  ..
040919 - Today, Millie less energetic could not go to the gym for aerobic
040920 - exercise. ref SDS 0 X64F  Did not go hiking at Lafayette nor at the
040921 - Clayton Safeway trail. because the hiking was too difficult, reported
040922 - on 090103, ref SDS H3 OT3L, due to rising side effects of falling
040923 - blood counts that cause fatigue, ref SDS 0 LF8M, from 13 cancer
040924 - treatments beginning on 081226, reported below. ref SDS 0 9I6T
040926 -  ..
040927 - NEUTS patient history of neutropenia from chemotherapy everyday with
040928 - cyclophosphamide reported in case study on 081205. ref SDS C5 EC5N
040930 -  ..
040931 - Neupogen treatments on 081219 and 081220 at Kaiser, ref SDS F6 UZ7K,
040932 - help maintain blood counts to strengthen Millie's immunity system,
040933 - shown in the schedule for Neupogen treatments updated on 081220.
040934 - ref SDS F6 HS5M
040935 -
040937 -  ..
040938 - Sunitinib Cyclophosmaide Methotrexate Patient History
040939 -
040940 - Follow up ref SDS H6 OE6K, ref SDS H5 OE6K.
040941 -
040943 -        Cycle 1  begin 081128 after 14 treatmenst sunitinib alone
040944 -        Cohort: 3
040946 -        ..
040947 -                                          Cyclophos  Metho
040948 -                               Sunitinib   phamide   trexate
040949 -       Days  Date  Time  Cycle    37.5       50        5
040950 -       =======================================================
040951 -       Follow up ref SDS H6 PA8Y, ref SDS H5 PA8Y.
040952 -
040953 -        1.  081114 0700  Load    37.5         0         0 ... ref SDS 94 OE6K
040954 -        2.  081115 0700  Load    75.0         0         0 ... ref SDS 95 OE6K
040955 -        3.  081116 0700  Load   112.5         0         0 ... ref SDS 96 OE6K
040956 -        4.  081117 0700  Load   150.0         0         0 ... ref SDS 97 OE6K
040957 -        5.  081118 0700  Load   187.5         0         0 ... ref SDS A0 OE6K
040958 -        6.  081119 0700  Load   225.0         0         0 ... ref SDS A2 OE6K
040959 -        7.  081120 0700  Load   263.5         0         0 ... ref SDS A3 OE6K
040960 -        8.  081121 0700  Load   301.0         0         0 ... ref SDS A4 OE6K
040961 -        9.  081122 0700  Load   338.5         0         0 ... ref SDS A5 OE6K
040962 -       10.  081123 0700  Load   376.0         0         0 ... ref SDS A6 OE6K
040963 -       11.  081124 0700  Load   413.5         0         0 ... ref SDS A7 OE6K
040964 -       12.  081125 0700  Load   451.0         0         0 ... ref SDS A8 OE6K
040965 -             ..
040966 -       13.  081126 0700  Load   488.5         0         0 ... ref SDS A9 OE6K
040967 -             ..
040968 -            081126 0820  NEUTS........1.50................... ref SDS B0 PU6K
040970 -             ..
040971 -       14.  081127 0700  Load   526.0         0         0 ... ref SDS B1 OE6K
040972 -       15.  081128 0700  1  1   563.5   1    50    1    5 ... ref SDS B4 OE6K
040973 -       16.  081129 0700  1  2   601.0   2   100    2   10 ... ref SDS B7 OE6K
040974 -       17.  081130 0700  1  3   638.5   3   150    2   10 ... ref SDS B8 OE6K
040975 -       18.  081201 0700  1  4   676.0   4   200    2   10 ... ref SDS B9 OE6K
040976 -       19.  081202 0700  1  5   713.5   5   250    2   10 ... ref SDS C1 OE6K
040977 -             ..
040978 -       20.  081203 0700  1  6   751.0   6   300    2   10 ... ref SDS C3 OE6K
040979 -
040980 -            081203 0735. NEUTS....... 0.624 ...... .......... ref SDS C2 RN5G
040981 -
040982 -                Rate of change per day = 1500 - 624 = 876 / 7
040983 -
040984 -                                       = 120+ per day
040986 -             ..
040987 -       21.  081204 0700  1  7   788.5   7   350    2   10 ... ref SDS C4 OE6K
040988 -             ..
040989 -       22.  081205 0700  1  8   826.0   8   400    3   15 ... ref SDS C5 OE6K
040990 -
040991 -            081205 1300  Neupogen...... 480 mcg  480......... ref SDS C6 KV84
040993 -             ..
040994 -       23.  081206 0700  1  9   863.5   9   450    4   20 ... ref SDS C9 OE6K
040995 -
040996 -            081206 0930  Neupogen...... 480 mcg  960......... ref SDS D0 BI4J
040998 -             ..
040999 -       24.  081207 0700  1 10   901.0  10   500    4   20 ... ref SDS D1 OE6K
041000 -       25.  081208 0700  1 11   938.5  11   550    4   20 ... ref SDS D2 OE6K
041001 -       26.  081209 0700  1 12   976.0  12   600    4   20 ... ref SDS D3 OE6K
041002 -             ..
041003 -       27.  081210 0700  1 13  1013.5  13   650    4   20 ... ref SDS D5 OE6K
041004 -
041005 -            081210 1301. NEUTS....... 1.085 ................. ref SDS D6 QY6H
041007 -             ..
041008 -       28.  081211 0700  1 14  1050.0  14   700    4   20 ... ref SDS D9 OE6K
041009 -             ..
041010 -       29.  081212 0700  1 15  1087.5  15   750    5   25 ... ref SDS E1 OE6K
041011 -
041012 -            081212 1115. NEUTS....... 1.054 ................. ref SDS E2 QY6H
041014 -             ..
041015 -       30.  081213 0700  1 16  1125.0  16   800    6   30 ... ref SDS E4 OE6K
041016 -       31.  081214 0700  1 17  1162.5  17   850    6   30 ... ref SDS E5 OE6K
041017 -       32.  081215 0700  1 18  1200.0  18   900    6   30 ... ref SDS E6 OE6K
041018 -       33.  081216 0700  1 19  1237.5  19   950    6   30 ... ref SDS E7 OE6K
041019 -             ..
041020 -       34.  081217 0700  1 20  1275.0  20  1000    6   30 ... ref SDS E8 OE6K
041021 -       35.  081218 0700  1 21  1312.5  21  1050    canceled.. ref SDS F0 OE6K
041022 -
041023 -            081218 0830. NEUTS....... 0.740 ................. ref SDS F1 QY6H
041025 -             ..
041026 -            081219 0700  2  1  paused until 081226........... ref SDS F3 OE6K
041028 -             ..
041029 -            081219 1130  Neupogen...... 480 mcg 1440 ........ ref SDS F4 UZ7K
041030 -            081220 0900  Neupogen...... 480 mcg 1920 ........ ref SDS F6 UZ7K
041032 -             ..
041033 -       36.  081226 0700  2  1  1350.0  22  1100.............. ref SDS G2 OE6K
041034 -       37.  081227 0700  2  2  1387.5  23  1150.............. ref SDS G4 OE6K
041035 -       38.  081228 0700  2  3  1425.0  24  1200.............. ref SDS G5 OE6K
041036 -       39.  081229 0700  2  4  1462.5  25  1250.............. ref SDS G6 OE6K
041037 -       40.  081230 0700  2  5  1500.0  26  1300.............. ref SDS G8 OE6K
041038 -       41.  081231 0700  2  6  1537.5  27  1350.............. ref SDS H0 OE6K
041039 -       42.  090101 0700  2  7  1575.0  28  1400.............. ref SDS H1 OE6K
041040 -       43.  090102 0700  2  8  1612.5  29  1450.............. ref SDS H2 OE6K
041041 -       44.  090103 0700  2  9  1650.0  30  1500.............. ref SDS H3 OE6K
041042 -       45.  090104 0700  2 10  1687.5  31  1550.............. ref SDS H4 OE6K
041043 -       46.  090105 0700  2 11  1725.0  32  1600.............. ref SDS H5 OE6K
041044 -       47.  090106 0700  2 12  1762.5  33  1650.............. ref SDS H6 OE6K
041045 -       48.  090107 0700  2 13  1800.0  34  1700.............. ref SDS 0 OE6K
041047 -  ..
041048 - Background on recent blood tests is reported on 081218. ref SDS F0
041049 - S18L
041051 -  ..
041052 - On 081230 case study dilemma cancer treatmnets cause low blood counts,
041053 - which prevents getting treatment; not getting treatment incerases
041054 - cancer; UCSF paused treatment for a week and prescribed Neupogen to
041055 - increase blood counts. ref SDS G7 I87N
041056 -
041057 -
041058 -
041059 -
041060 -
0411 -

SUBJECTS
Default Null Subject Account for Blank Record

0503 -
050401 -  ..
050402 - Side Effects Sunitinib Study with Cyclophosphamide Methotrexate
050403 -
050404 - Follow up ref SDS H6 LF8M, ref SDS H5 LF8M.
050405 -
050406 - Fatigue is a likely side effect of sunitinib with cyclophosphamide,
050407 - listed in the Consent document reviewed on 081017. ref SDS 76 4G7G
050409 -  ..
050410 - Blood counts NEUTS 1.710 reported on 081226, ref SDS G3 B35J, enabled
050411 - increased energy shown by exercise reported on 090102. ref SDS H2 6M7G
050412 - Getting 13 daily cancer treatments starting on 081226, shown by
050413 - patient history above, ref SDS 0 9I6T, has caused side effects of
050414 - fatigue to rise again, indicating blood counts are falling again.
050416 -  ..
050417 - Today, Millie less energetic could not work out in the gym for aerobic
050418 - exercise. ref SDS 0 X64F, Did not go hiking at Lafayette nor at the
050419 - Clayton Safeway trail, reported below, ref SDS 0 3E4K, because hiking
050420 - was difficult on Millie's legs, reported on 090102, ref SDS H2 6E7G,
050421 - due to rising side effects of fatigue from 13 cancer treatments
050422 - beginning on 081226, shown above, ref SDS 0 9I6T, that are now causing
050423 - blood counts to fall again,
050425 -  ..
050426 - Background on Neupogen treatments and UCSF comments are reported on
050427 - 081207. ref SDS D1 673J
050429 -  ..
050430 - NEUTS blood tests show patient history of treatments with Nuepogen to
050431 - recover from neutropenia caused by getting chemotherapy everyday with
050432 - cyclophosphamide reported in case study on 081205. ref SDS C5 EC5N
050434 -  ..
050435 - Schedule for Neupogen treatments is listed on 081220. ref SDS F6 WJ4O
050437 -  ..
050438 - Feet and toes continue better today, less sensitive to walking that
050439 - was reported during the meeting at UCSF on 081218. ref SDS F2 HM4M
050440 - Subsiding side effects restoring normal use of feet enabled hiking,
050441 - but Millie is tired today, so we did not go hiking, per below.
050442 - ref SDS G5 X64F
050444 -  ..
050445 - Joint pain, discomfort, and total ill feeling, commonly associated
050446 - with chemotherapy, reported on 081218, ref SDS F0 E38H, and discussed
050447 - with the medical team at UCSF also on 081218, ref SDS F2 QW7H, has now
050448 - mostly disipated, as a result of the doctor stopping all treatment for
050449 - 1 week, ref SDS F2 QW48, as shown in patient history above.
050450 - ref SDS G5 053F
050452 -  ..
050453 - Interstitional lung disease discussed in the record on 081218,
050454 - ref SDS F0 KM5F, shows no evident symptoms.
050456 -  ..
050457 - Vitals were reported today at the meeting at Kaiser with the primary
050458 - care physician...
050459 -
050460 -                   BP *** ** pulse **
050462 -  ..
050463 - Millie reports continued relief from heartburn with daily treatments
050464 - using Prilosce started on 081208. ref SDS D2 7J6K
050466 -  ..
050467 - Sore throat problem, reported initially on 081218, as having begun
050468 - days earlier, ref SDS F0 2B8M, seems better today today continuing
050469 - relief reported yesterday on 081222. ref SDS F8 TT4O  This increases
050470 - interest in eating food.  Millie had eggs and a baggel for a late
050471 - lunch after returning from the gym.  Swallowing seems much more normal
050472 - now.
050474 -  ..
050475 - Millie reports improved taste from some foods today (e.g., soup),
050476 - cited in study consent documents, reviewed on 081017. ref SDS 76 6T5H
050478 -     ..
050479 -                                   Date
050480 -    Description Adverse Event   Start  Stop     Medication
050481 -    ---------------------------------------------------------
050482 -    Follow up ref SDS H6 MV5H, ref SDS H5 MV5H.
050483 -
050484 -    Diarrhea                    081114 081114   Imodium........ ref SDS 94 LF8M
050485 -    Low pulse                   081120 081120   None........... ref SDS A3 LF8M
050486 -    Low pulse                   081121 081121   None........... ref SDS A4 7G8M
050487 -    BP 144 84 Pulse 48          081121 081121   Hiking......... ref SDS A4 LF8M
050488 -    Joint pain minor            081121 081121   Hiking......... ref SDS A4 LF8M
050489 -    Fatigue minor               081121 081121   Hiking......... ref SDS A4 LF8M
050490 -    Low pulse                   081122 081122   None........... ref SDS A5 7G8M
050491 -    Fatigue minor               081122 081122   Hiking......... ref SDS A5 LF8M
050492 -    Low pulse                   081123 081122   None........... ref SDS A6 7G8M
050493 -    BP 121 74 Pulse 53          081123 081123   Hiking......... ref SDS A6 LF8M
050494 -    Fatigue minor               081123 081122   Hiking......... ref SDS A6 LF8M
050495 -    Joint pain minor            081124 081124   Hiking......... ref SDS A7 LF8M
050496 -    Fatigue minor               081124 081124   Hiking......... ref SDS A7 LF8M
050497 -    Heartburn                   081124 081124   None........... ref SDS A7 HS9K
050498 -    BP 144 78 Pulse 52          081125 081125   Hiking......... ref SDS A8 LF8M
050499 -    Joint pain minor            081125 081125   Hiking......... ref SDS A8 LF8M
050500 -    Fatigue minor               081125 081125   Hiking......... ref SDS A8 LF8M
050501 -    Heartburn                   081125 081125   None........... ref SDS A8 HS9K
050502 -    Heartburn                   081126 081126   None........... ref SDS A9 HS9K
050503 -    Heartburn                   081127 081127   None........... ref SDS B3 HS9K
050504 -    BP 135 73 Pulse 48          081128 081128   Hiking......... ref SDS B4 5X6K
050505 -    Upset stomach               081128 081128   Hiking......... ref SDS B4 T76O
050506 -    BP 140 75 Pulse 50          081129 081129   Hiking......... ref SDS B7 5X6K
050507 -    Heartburn                   081129 081129   None........... ref SDS B7 HS9K
050508 -     ..
050509 -    Fatigue                     081129 081129   Rest........... ref SDS B7 LF8M
050510 -    Fatigue                     081130 081130   Rest........... ref SDS B8 LF8M
050511 -    BP 136 79 Pulse 46          081201 081201   Hiking......... ref SDS B9 5X6K
050512 -    Fatigue                     081201 081201   Rest........... ref SDS B9 LF8M
050513 -    Taste altered               081201 081201   Rest........... ref SDS B9 VP4G
050514 -    BP 141 77 Pulse 46          081202 081202   Aerobics gym... ref SDS C1 5X6K
050515 -    Fatigue                     081202 081202   Rest........... ref SDS C1 LF8M
050516 -    Taste altered               081202 081202   Rest........... ref SDS C1 VP4G
050517 -    BP 138 77 Pulse 48          081203 081203   Hiking......... ref SDS C3 5X6K
050518 -    Fatigue                     081203 081203   Rest........... ref SDS C3 LF8M
050519 -    Taste altered               081203 081203   Rest........... ref SDS C3 VP4G
050520 -    NEUTS (ANC)     0.624       081203 081203   Neupogen.......
050521 -    BP 133 72 Pulse 45          081204 081204   Rest........... ref SDS C4 5X6K
050522 -    Fatigue                     081204 081204   Rest........... ref SDS C4 LF8M
050523 -    Taste altered               081204 081204   Rest........... ref SDS C4 VP4G
050524 -    BP 138 76 Pulse 49          081205 081205   Rest........... ref SDS C5 5X6K
050525 -    Diarrhea                    081205 081114   Imodium........ ref SDS C5 Q67F
050526 -    Fatigue                     081205 081205   Rest........... ref SDS C5 LF8M
050527 -    Taste altered               081205 081205   Rest........... ref SDS C5 VP4G
050528 -    BP *** ** Pulse **          081206 081206   Rest........... ref SDS C9 5X6K
050529 -    Fatigue                     081206 081206   Rest........... ref SDS C9 LF8M
050530 -    BP 128 70 Pulse 53          081207 081207   Hiking......... ref SDS D1 5X6K
050531 -    Fatigue                     081207 081207   Rest........... ref SDS D1 LF8M
050532 -    BP 137 68 Pulse 53          081208 081208   Rest........... ref SDS D2 5X6K
050533 -    Fatigue                     081208 081208   Rest........... ref SDS D2 LF8M
050534 -    BP *** ** Pulse **          081209 081209   Rest........... ref SDS D2 5X6K
050535 -    Fatigue                     081209 081209   Rest........... ref SDS D2 LF8M
050536 -    Heartburn                   081209 081209   Prilosec....... ref SDS D3 7J6K
050537 -    BP 136 70 Pulse 53          081210 081210   Rest........... ref SDS D5 5X6K
050538 -    Fatigue                     081210 081210   Rest........... ref SDS D5 LF8M
050539 -    Heartburn                   081210 081210   Prilosec....... ref SDS D5 7J6K
050540 -    BP *** ** Pulse **          081211 081211   Rest........... ref SDS D9 5X6K
050541 -    Fatigue                     081211 081211   Exercise gym... ref SDS D9 LF8M
050542 -    Heartburn                   081211 081211   Prilosec....... ref SDS D9 7J6K
050543 -    BP 137 76 Pulse 53          081212 081212   Rest........... ref SDS E1 5X6K
050544 -    Fatigue                     081212 081212   Exercise gym... ref SDS E1 LF8M
050545 -    Heartburn                   081212 081212   Prilosec....... ref SDS E1 7J6K
050546 -    BP 147 80 Pulse 51          081213 081213   Rest........... ref SDS E4 5X6K
050547 -    Fatigue                     081213 081213   Exercise gym... ref SDS E4 LF8M
050548 -    BP *** ** Pulse **          081214 081214   Rest........... ref SDS E5 5X6K
050549 -    Fatigue                     081214 081214   Rest........... ref SDS E5 LF8M
050550 -    BP *** ** Pulse **          081215 081215   Rest........... ref SDS E6 5X6K
050551 -    Fatigue                     081215 081215   Rest........... ref SDS E6 LF8M
050552 -    BP 144 79 Pulse 54          081216 081216   Rest........... ref SDS E7 5X6K
050553 -    Fatigue                     081216 081216   Exercise gym... ref SDS E7 LF8M
050554 -     ..
050555 -    Joint pain minor            081216 081216   Rest........... ref SDS E7 E38H
050556 -    BP 137 69 Pulse 63          081217 081217   Rest........... ref SDS E8 5X6K
050557 -    Fatigue                     081217 081217   Rest........... ref SDS E8 LF8M
050558 -    Joint pain minor            081217 081217   Rest........... ref SDS E8 E38H
050559 -    Nosebleed minor             081217 081217   Rest........... ref SDS E8 ZF5F
050560 -     ..
050561 -    BP *** ** Pulse **          081218 081218   Rest........... ref SDS F0 5X6K
050562 -    Fatigue                     081218 081218   Rest........... ref SDS F0 LF8M
050563 -    Joint pain minor            081218 081218   Rest........... ref SDS F0 E38H
050564 -    Nosebleed moderate          081218 081218   Rest........... ref SDS F0 ZF5F
050565 -    Throat pain eating          081218 081218   Eating less.... ref SDS F0 2B8M
050566 -    BP 155 84 Pulse 53          081219 081219   Rest........... ref SDS F3 5X6K
050567 -    Fatigue                     081121 081219   Rest........... ref SDS F3 LF8M
050568 -    Feet toes lesions           081219 081219   Rest........... ref SDS F3 UO8I
050569 -    Joint pain ill feeling      081121 081219   Rest........... ref SDS F3 E38H
050570 -    Throat sore eating          081218 081219   Eating less.... ref SDS F3 TT4O
050571 -    BP 123 69 pulse 53          081220 081220   Rest........... ref SDS F5 5X6K
050572 -    Fatigue                     081121 081220   Rest........... ref SDS F5 LF8M
050573 -    Feet toes lesions           081219 081220   Rest........... ref SDS F5 UO8I
050574 -    Joint pain ill feeling      081121 081220   Rest........... ref SDS F5 E38H
050575 -    Throat sore eating          081218 081220   Eating less.... ref SDS F5 TT4O
050576 -    BP 117 71 pulse 65          081221 081221   Rest........... ref SDS F7 5X6K
050577 -    Fatigue                     081121 081221   Rest........... ref SDS F7 LF8M
050578 -    Feet toes lesions           081219 081221   Rest........... ref SDS F7 UO8I
050579 -    Joint pain ill feeling      081121 081221   Rest........... ref SDS F7 E38H
050580 -    Throat sore eating          081218 081221   Eating less.... ref SDS F7 TT4O
050581 -    BP 117 71 pulse 65          081222 081222   Rest........... ref SDS F8 5X6K
050582 -    Fatigue                     081121 081222   Rest........... ref SDS F8 LF8M
050583 -    Feet toes lesions           081219 081222   Rest........... ref SDS F8 UO8I
050584 -    Joint pain ill feeling      081121 081222   Rest........... ref SDS F8 E38H
050585 -    Throat sore eating          081218 081222   Eating less.... ref SDS F8 TT4O
050586 -    BP 143 68 pulse 65          081223 081223   Rest........... ref SDS F8 5X6K
050587 -    Fatigue more energy         081121 081223   Exercise gym... ref SDS F9 LF8M
050588 -    Feet feel better            081219 081223   Exercise gym... ref SDS F9 UO8I
050589 -    Joint pain subsides         081121 081223   Exercise gym... ref SDS F9 E38H
050590 -    Throat sore improved        081218 081223   Eating normal.. ref SDS F9 TT4O
050591 -    BP *** ** pulse **          081224 081224   Rest........... ref SDS G0 5X6K
050592 -    Fatigue more energy         081121 081224   Exercise gym... ref SDS G0 LF8M
050593 -    Feet feel better            081219 081224   Exercise gym... ref SDS G0 UO8I
050594 -    Joint pain subsides         081121 081224   Exercise gym... ref SDS G0 E38H
050595 -    Throat sore improved        081218 081224   Eating normal.. ref SDS G0 TT4O
050596 -    BP 124 80 pulse 66          081225 081225   Rest........... ref SDS G1 5X6K
050597 -    Fatigue more energy         081121 081225   Activity....... ref SDS G1 LF8M
050598 -    Fatigue more energy         081121 081226   Activity....... ref SDS G2 LF8M
050599 -    BP *** ** pulse **          081227 081227   Rest........... ref SDS G4 5X6K
050600 -    Fatigue more energy         081121 081227   Hiking......... ref SDS G4 LF8M
050601 -    BP *** ** pulse **          081228 081228   Rest........... ref SDS G5 5X6K
050602 -    Fatigue more energy         081121 081228   Rest........... ref SDS G5 LF8M
050603 -    BP *** ** pulse **          081229 081229   Rest........... ref SDS G6 5X6K
050604 -    Fatigue more energy         081121 081229   Rest........... ref SDS G6 LF8M
050605 -    BP *** ** pulse **          081230 081230   Rest........... ref SDS G8 5X6K
050606 -    Diarrhea                    081230 081230   Imodium........ ref SDS G8 KZ9N
050607 -    Fatigue more energy         081121 081230   Rest........... ref SDS G8 LF8M
050608 -    BP *** ** pulse **          081231 081231   Rest........... ref SDS H0 5X6K
050609 -    Fatigue more energy         081121 081231   Rest........... ref SDS H0 LF8M
050610 -    BP *** ** pulse **          090101 090101   Rest........... ref SDS H1 5X6K
050611 -    Fatigue more energy         081121 090101   Hiking......... ref SDS H1 LF8M
050612 -    BP *** ** pulse **          090102 090102   Rest........... ref SDS H2 5X6K
050613 -    Fatigue more energy         081121 090102   Hiking......... ref SDS H2 LF8M
050614 -    BP *** ** pulse **          090103 090103   Rest........... ref SDS H3 5X6K
050615 -    Fatigue less energy         081121 090103   Exercise gym... ref SDS H3 LF8M
050616 -    BP *** ** pulse **          090104 090104   Rest........... ref SDS H4 5X6K
050617 -    Fatigue less energy         081121 090104   Rest........... ref SDS H4 LF8M
050618 -    BP *** ** pulse **          090105 090105   Rest........... ref SDS H5 5X6K
050619 -    Fatigue less energy         081121 090105   Rest........... ref SDS H5 LF8M
050620 -    BP *** ** pulse **          090106 090106   Rest........... ref SDS H6 5X6K
050621 -    Fatigue less energy         081121 090106   Exercise gym... ref SDS H6 LF8M
050622 -    BP *** ** pulse **          090107 090107   Rest........... ref SDS H6 5X6K
050623 -    Fatigue less energy         081121 090107   Rest........... ref SDS 0 LF8M
050624 -
050625 -
050626 -
0507 -

SUBJECTS
Default Null Subject Account for Blank Record

0603 -
060401 -  ..
060402 - Exercise Hiking Maintain Fitness Strengthen Immune System
060403 -
060404 - Follow up ref SDS H6 3E4K, ref SDS H5 3E4K.
060405 -
060406 - Today, Millie less energetic could not work out in the gym for aerobic
060407 - exercise. ref SDS 0 X64F, Did not go hiking at Lafayette nor at the
060408 - flatter Clayton Safeway trail, because hiking was difficult on
060409 - Millie's legs, reported on 090102, ref SDS H2 6E7G, due to rising side
060410 - effects of fatigue from 13 cancer treatments beginning on 081226,
060411 - ref SDS 0 9I6T, that are now causing blood counts to fall again,
060412 - reported above. ref SDS 0 LF8M
060414 -  ..
060415 - NEUTS blood tests show patient history treatments with Nuepogen for
060416 - neutropenia from chemotherapy everyday with cyclophosphamide reported
060417 - in case study on 081205. ref SDS C5 EC5N
060419 -  ..
060420 - On 081110, Millie complained about difficulty lifting herself from a
060421 - full squatting position. ref SDS 90 HX67  For several weeks, she was
060422 - exercising to strengthen legs, and arms, shown by going to the gym on
060423 - 081211. ref SDS D9 3E4K  Rising fatigue now prevents continuing
060424 - exercise.
060425 -
060427 -  ..
060428 - Case Study on Pateint History Exercising
060429 -
060430 - Follow up ref SDS H6 X64F, ref SDS H5 X64F.
060431 -
060432 -                                              +- scm = Sunitinib Cyclophosphmaide Methotrexate
060433 -                                              +- sc  = Sunitinib Cyclophosphmaide
060434 -                           Time     Pulse     |
060435 -    Location        Miles Minutes  Avg Max  Chem  Neupo  Date
060436 -    ----------------------------------------------------------------
060437 -    Concord home                              sc        090107, ref SDS 0 3E4K
060438 -    Concord home (gym)                        sc        090106, ref SDS H6 3E4K
060439 -    Concord home                              sc        090105, ref SDS H5 3E4K
060440 -    Concord home                              sc        090104, ref SDS H4 3E4K
060441 -    Concord home (gym)                        sc        090103, ref SDS H3 3E4K
060442 -    Clayton Safeway  3.00   58.7    83  94    sc        090102, ref SDS H2 3E4K
060443 -    Lafayette        2.75   58.4    87 103    sc        090101, ref SDS H1 3E4K
060444 -    Concord home                              sc        081231, ref SDS H0 3E4K
060445 -    Concord home                              sc        081230, ref SDS G8 3E4K
060446 -    Concord home                              sc        081229, ref SDS G6 3E4K
060447 -    Concord home                              sc        081228, ref SDS G5 3E4K
060448 -    Lafayette        2.75   56.2    90 112    sc        081227, ref SDS G4 3E4K
060449 -    Concord home                              sc        081226, ref SDS G2 3E4K
060450 -    Concord travel                                      081225, ref SDS G1 3E4K
060451 -    Concord home                                        081224, ref SDS G0 3E4K
060452 -    Concord home (gym)                                  081223, ref SDS F9 3E4K
060453 -    Concord home                                        081222, ref SDS F8 3E4K
060454 -    Concord home                                        081221, ref SDS F7 3E4K
060455 -    Concord home                                        081220, ref SDS F5 3E4K
060456 -    Concord home                                        081219, ref SDS F3 3E4K
060457 -    Concord home                              sc        081218, ref SDS F0 3E4K
060458 -    Concord home                              sc        081217, ref SDS E8 3E4K
060459 -    Concord home (gym)                        sc        081216, ref SDS E7 3E4K
060460 -    Concord home                              sc        081215, ref SDS E6 3E4K
060461 -    Concord home                              sc        081214, ref SDS E5 3E4K
060462 -    Concord home (gym)                        scm       081213, ref SDS E4 3E4K
060463 -    Concord home                              scm       081212, ref SDS E1 3E4K
060464 -    Concord home (gym)                        sc        081211, ref SDS D9 3E4K
060465 -    Concord home                              sc        081210, ref SDS D5 3E4K
060466 -    Concord home                              sc        081209, ref SDS D3 3E4K
060467 -    Concord home                              sc        081208, ref SDS D2 3E4K
060468 -    Lafayette        4.75   78.6    95 110    sc        081207, ref SDS D1 3E4K
060469 -    Concord home                              scm       081206, ref SDS C9 3E4K
060470 -    Concord home                              scm       081205, ref SDS C5 3E4K
060471 -    Concord home                              sc        081204, ref SDS C4 3E4K
060472 -    Lafayette        2.75   62.7    90 117    sc        081203, ref SDS C3 3E4K
060473 -    Concord home (gym)                        sc        081202, ref SDS C1 3E4K
060474 -    Lafayette        5.50  102.3    95 122    sc        081201, ref SDS B9 3E4K
060475 -    Concord home                              sc        081130, ref SDS B8 3E4K
060476 -    Lafayette        2.75   56.7    90 115    scm       081129, ref SDS B7 3E4K
060477 -    Lafayette        2.75   46.5   100 128    scm       081128, ref SDS B4 3E4K
060478 -    Lafayette        5.50   93.3   100 122    s         081127, ref SDS B3 3E4K
060479 -    Concord home                              s         081126, ref SDS A9 3E4K
060480 -    Lafayette        4.00   73.7   105 127    s         081125, ref SDS A8 3E4K
060481 -    Lafayette        5.50   91.4   100 129    s         081124, ref SDS A7 3E4K
060482 -    Concord home                              s         081123, ref SDS A6 3E4K
060483 -    Lafayette        5.50   92.8    95 122    s         081122, ref SDS A5 3E4K
060484 -    Lafayette        5.50   94.4    85 112    s         081121, ref SDS A4 3E4K
060485 -    Lafayette        5.50   94.7    90 122    s         081120, ref SDS A3 3E4K
060486 -    San Francisco    1.00   60.0    65  75    s         081119, ref SDS A2 3E4K
060487 -    Lafayette        2.75   49.2    97 130    s         081118, ref SDS A1 3E4K
060488 -    Lafayette        5.50   93.6   115 138    s         081117, ref SDS 98 3E4K
060489 -    Concord home                              s         081116, ref SDS 96 Y68J
060490 -    Concord home                              s         081115, ref SDS 95 EK7I
060491 -    Concord home                              s         081114, ref SDS 94 XW6H
060492 -    Lafayette        5.50   94.2   115 138              081110, ref SDS 90 3E4K
060493 -    Lafayette        2.75   48.4   105 128              081109, ref SDS 89 3E4K
060494 -    Kaiser                                         x    081108, ref SDS 88 UZ7K
060495 -    Kaiser                                         x    081107, ref SDS 87 UZ7K
060496 -    Lafayette        5.50   90.2   120 143              081025, ref SDS 83 3E4K
060497 -    Kaiser                                         x    081025, ref SDS 83 UZ7K
060498 -    Kaiser                                         x    081024, ref SDS 82 UZ7K
060499 -    UCSF                                      c         081023, ref SDS 81 V94O
060500 -    Lafayette        5.50   90.6   115 141              081021, ref SDS 80 3E4K
060501 -    Lafayette        5.50   90.4   110 128              081020, ref SDS 79 3E4K
060502 -    Kaiser                                         x    081018, ref SDS 78 UZ7K
060503 -    Kaiser                                         x    081017, ref SDS 77 UZ7K
060504 -    UCSF                                      e         081016, ref SDS 75 V94O
060505 -    Lafayette        5.50   90.1   115 154              081014, ref SDS 74 3E4K
060506 -    Lafayette        5.50   92.7   115 138              081013, ref SDS 73 3E4K
060507 -    Lafayette        8.25  146.4   180 224              081012, ref SDS 72 3E4K
060508 -    Kaiser                                         x    081011, ref SDS 71 UZ7K
060509 -    Lafayette        5.50   93.3   116 138              081010, ref SDS 70 3E4K
060510 -    Kaiser                                         x    081010, ref SDS 70 UZ7K
060511 -    UCSF                                      e         081009, ref SDS 69 V94O
060512 -    Lafayette        5.50   92.1   113 137              081006, ref SDS 68 3E4K
060513 -    Lafayette        2.75   48.5   110 136         x    081004, ref SDS 67 3E4K
060514 -    Lafayette        5.50   98.2   117 136         x    081003, ref SDS 66 3E4K
060515 -    UCSF                                      c         081002, ref SDS 65 V94O
060516 -    Lafayette        5.50   94.7   115 142              080929, ref SDS 64 3E4K
060517 -    Lafayette        8.25  150.4   115 135              080928, ref SDS 64 3E4K
060518 -    Kaiser                                         x    080927, ref SDS 63 UZ7K
060519 -    Lafayette        5.50   90.2   120 140         x    080926, ref SDS 62 3E4K
060520 -    UCSF                                      c         080925, ref SDS 61 V94O
060521 -    Lafayette        5.50   92.3   116 138              080923, ref SDS 60 3E4K
060522 -    Lafayette        5.50   98.4   112 134              080922, ref SDS 60 3E4K
060523 -    Lafayette        5.50   98.2   114 137              080921, ref SDS 60 3E4K
060524 -    Lafayette        5.50  101.6   110 133         x    080920, ref SDS 59 3E4K
060525 -    Lafayette        5.50   89.3   115 144         x    080919, ref SDS 58 3E4K
060526 -    UCSF                                      c         080918, ref SDS 57 V94O
060527 -    Lafayette        2.75   46.2   117 139              080916, ref SDS 58 3E4K
060528 -    Lafayette        5.50   91.8   117 142              080915, ref SDS 56 3E4K
060529 -    Clayton Safeway  3.00   62.4    98 118              080914, ref SDS 55 3E4K
060530 -    Lafayette        8.25  129.7   123 147         x    080913, ref SDS 54 3E4K
060531 -    Lafayette        5.50   88.4   118 146         x    080912, ref SDS 53 3E4K
060532 -    UCSF                                      c         080911, ref SDS 52 V94O
060533 -    Lafayette        2.75   46.8   113 140              080909
060534 -    Lafayette        5.50   89.2   117 143              080908
060535 -    Lafayette        5.50   92.1   115 138              080907
060536 -    Lafayette        2.75   45.3   120 144         x    080906, ref SDS 51 3E4K
060537 -    Lafayette        2.75   56.8    93 120         x    080905, ref SDS 50 3E4K
060538 -    UCSF                                      c         080904, ref SDS 49 V94O
060539 -    Lafayette        8.25  140.4   116 131              080903
060540 -    Lafayette        5.50   94.9   115 134              080902
060541 -    Kaiser                                         x    080830
060542 -    Kaiser                                         x    080829
060543 -    UCSF                                      c         080828, ref SDS 48 V94O
060544 -    Lafayette        5.50   93.6   120 137              080826
060545 -    Lafayette        5.50   93.2   117 138              080825
060546 -    Lafayette        5.50   93.2   123 136         x    080823
060547 -    Lafayette        8.25  142.5   110 131         x    080822, ref SDS 47 3E4K
060548 -    UCSF                                      e         080821, ref SDS 46 V94O
060549 -    Lafayette        5.50   94.7   115 137              080820
060550 -    Lafayette        5.50   94.3   115 135              080819
060551 -    Lafayette        8.25  141.7   118 134              080815
060552 -    UCSF                                      e         080814, ref SDS 45 V94O
060553 -    Lafayette        5.50   93.8   120 136              080813
060554 -    Lafayette        5.50   94.4   116 139              080812
060555 -    Lafayette        5.50   94.2   119 133              080810
060556 -    Lafayette        8.25  143.6   114 132         x    080809, ref SDS 43 3E4K
060557 -    Lafayette        8.25  141.1   117 135         x    080808, ref SDS 42 3E4K
060558 -    UCSF                                      c         080807, ref SDS 41 V94O
060559 -    Lafayette        8.25  143.7   115 132              080805
060560 -    Concord          7.00  127.6   105 118              080804
060561 -    Lafayette        8.25  143.2   112 134              080802
060562 -    Lafayette        5.50   93.4   115 138              080801
060563 -    Lafayette        5.50   92.2   118 140              080729
060564 -    Lafayette        5.50   92.6   116 137              080728
060565 -    Lafayette        8.25  142.6   114 134              080727
060566 -    Lafayette        5.50   91.5   120 143              080726
060567 -    Lafayette        8.25  140.8   117 135              080725
060568 -    Lafayette        5.50   91.8   122 141              080723
060569 -    Lafayette        5.50   91.3   120 139              080722
060570 -    Lafayette        8.25  143.3   115 133              080720
060571 -    Lafayette        5.50   90.7   125 144              080719
060572 -    Lafayette        5.50   92.4   123 142              080716
060573 -    Lafayette        2.25   46.8   116 137              080715
060574 -    Lafayette        8.25  141.8   116 136              080712
060575 -    Lafayette        5.50   92.9   116 139              080711
060576 -    Lafayette        8.25  143.3   113 137              080704
060577 -    Lafayette        5.50   90.2   121 147              080630
060578 -    Lafayette        8.25  142.4   116 138              080628
060579 -    Lafayette        5.50   91.4   118 138              080625
060580 -    Lafayette        2.25   47.9   116 136              080623
060581 -    Lafayette        5.50   94.2   112 138              080622
060582 -    Lafayette        5.50   94.7   115 133              080621
060583 -    Lafayette        2.25   48.3   110 129              080620
060584 -    Mt Diablo        7.00  129.4   130 153              080616
060585 -    Lafayette        5.50   90.8   120 146              080615
060586 -    Lafayette        5.50   91.3   124 144              080614
060587 -    Lafayette        5.50   89.7   122 143              080613
060588 -    Lafayette        2.76   45.8   120 147              080611
060589 -    Lafayette        5.50   90.5   123 145              080609
060590 -    Lafayette        5.50   92.7   115 138              080607
060591 -    Lafayette        5.50   94.2   118 139              080602
060592 -    Lafayette        5.50   96.2   110 202              080507, ref SDS 19 WO8M
060593 -
060594 -
060595 -
060596 -
060597 -
060598 -
0606 -