THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net
S U M M A R Y
DIARY: November 19, 2008 07:00 AM Wednesday;
Rod Welch
Millie treatment #6 IBC 5th relapse sunitinib clinical study.
1...Summary/Objective
........Patient History Sunitinib Loading Dose 14 Days
2...Side Effects Sunitinib Study
3...Exercise Hiking Maintain Fitness Strengthen Immune System
4...Case Study on Pateint History Exercising
5...Side Effects Neupogen Treatments Increase May Be Chemotherapy
..............
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CONTACTS
SUBJECTS
Default Null Subject Account for Blank Record
0403 -
0403 - ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 67 0000. ref SDS 64 0000.
040502 -
040503 -
040504 -
040505 -
040507 - ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - On 081113 Millie received sunitinib drugs from UCSF to treat the 5th
040902 - relapse of IBC.
040904 - ..
040905 - Millie began the 14 day "charging" treatment on 081114. ref SDS 61 EK7I
040906 - After 14 treatments, if Millie tolerates sunitinib at the prescribed
040907 - dose, then she begins adding 2 chemotherapy drugs once a day for 2
040908 - days a week as prescribed in the treatment protocol, reviewed on
040909 - 081017. ref SDS 47 004O
040911 - ..
040912 - Millie needs a prescription from UCSF for chemotherapy drugs, as
040913 - reported on 081117, ref SDS 64 ID7I, and prior to meeting at UCSF on
040914 - 081126, which was requested in a letter to the medical team on 081117.
040915 - ref SDS 66 FQ5I
040916 -
040918 - ..
040919 - Patient History Sunitinib Loading Dose 14 Days
040920 -
040921 - Follow up ref SDS 67 OE6K, ref SDS 64 OE6K.
040922 -
040924 - Cycle 1
040925 - Cohort: 3
040927 - ..
040928 - Sunitinib MG Cyclophos Metho
040929 - Amount Today Cum phamide trexate
040930 - Days Date Time Cycle 25 12.5 Total Total Amnt Total Amnt Total
040931 - --------------------------------------------------------------------
040932 - Follow up ref SDS 67 PA8Y, ref SDS 64 PA8Y.
040933 -
040934 - 1. 081114 0700 1 1 1 37.5 37.5 0 0 0 0 ... ref SDS 4 OE6K
040935 - 2. 081115 0700 1 1 1 37.5 75.0 0 0 0 0 ... ref SDS 5 OE6K
040936 - 3. 081116 0700 1 1 1 37.5 112.5 0 0 0 0 ... ref SDS 6 OE6K
040937 - 4. 081117 0700 1 1 1 37.5 150.0 0 0 0 0 ... ref SDS 7 OE6K
040938 - 5. 081118 0700 1 1 1 37.5 187.5 0 0 0 0 ... ref SDS 10 OE6K
040939 - 6. 081119 0700 1 1 1 37.5 225.0 0 0 0 0 ... ref SDS 0 OE6K
040940 -
040941 -
040942 -
040943 -
0410 -
SUBJECTS
Default Null Subject Account for Blank Record
0503 -
050401 - ..
050402 - Side Effects Sunitinib Study
050403 -
050404 - Follow up ref SDS 67 LF8M, ref SDS 64 LF8M.
050405 -
050406 - Millie reported no side effects today.
050408 - ..
050409 - Millie's record of exercising shows correlation between treatments and
050410 - exercise as an indicator of adverse side effects. ref SDS 65 8G5M
050412 - ..
050413 - Millie also has side effects from Neupogen, reported today.
050414 - ref SDS 65 XQ4L
050416 - ..
050417 - Date
050418 - Description Adverse Event Start Stop Medication
050419 - ---------------------------------------------------------
050420 - Follow up ref SDS 67 LF8M, ref SDS 64 LF8M.
050421 -
050422 - Diarea 081114 081114 Imodium, ref SDS 61 LF8M
050423 -
050424 -
050425 -
050426 -
050427 -
0505 -
SUBJECTS
Default Null Subject Account for Blank Record
0603 -
060401 - ..
060402 - Exercise Hiking Maintain Fitness Strengthen Immune System
060403 -
060404 - Follow up ref SDS 68 3E4K, ref SDS 65 3E4K.
060405 -
060406 - Bone pain, fatigue, and headache from Neupogen have not recurred since
060407 - the report last week on 081110. ref SDS 59 3E4K
060409 - ..
060410 - Millie has not had another attack of Cellulitis and lymphedema since
060411 - going to the emergency care unit on 080409. ref SDS 2 0001 There was
060412 - a slight flare up on 080520. ref SDS 4 OU5J
060414 - ..
060415 - Millie had her 5th treatment with sunitinib this morning at 0700.
060416 - ref SDS 0 PA8Y
060418 - ..
060419 - Millie went to San Francisco this morning at 0900 with friends to
060420 - visit the recently rennovated Acacemy of Natural Science across from
060421 - the DeYoung Museum in Golden Gate park.
060423 - ..
060424 - This morning Millie feels well rested, after reporting being a little
060425 - more tired than usual yesterday after working out in the gym, and
060426 - hiking only 1 lap at Lafayette reservoir, about 2.75 miles.
060427 - ref SDS 68 SV6K
060429 - ..
060430 - Last week on 081110, Millie complained about diffiuclty lifting
060431 - herself from a full squatting position. ref SDS 59 HX67 She has since
060432 - been exercising to strengthen her legs, and arms.
060434 - ..
060435 - This morning Millie did...
060436 -
060437 - Arm presses 3 sets of 10 leaning against bannister.
060438 - Squats 3 sets of 10 vary depth useing bannister for leverage
060440 - ..
060441 - There have been no indications of Cellulitis nor lymphedema that has
060442 - occurred previously with exercising the left arm, reported on 070607.
060443 - ref SDS 1 ZH6I
060445 - ..
060446 - Case Study on Pateint History Exercising
060447 -
060448 -
060449 - +- s = Sunitinib
060450 - +- c = Carboplatin
060451 - +- e = Erbatex cetuximab
060452 - Time Pulse |
060453 - Location Miles Minutes Avg Max Chem Neupo Date
060454 - ----------------------------------------------------------------
060455 - San Francisco 1.00 60.0 65 75 s 081119, ref SDS 0 3E4K
060456 - Lafayette 2.75 49.2 97 130 s 081118, ref SDS 68 3E4K
060457 - Lafayette 5.50 93.6 115 138 s 081117, ref SDS 65 3E 4K
060458 - Concord home s 081116, ref SDS 63 Y6 8J
060459 - Concord home s 081115, ref SDS 62 EK 7I
060460 - Concord home s 081114, ref SDS 61 XW 6H
060461 - Lafayette 5.50 94.2 115 138 081110, ref SDS 59 3E4K
060462 - Lafayette 2.75 48.4 105 128 081109, ref SDS 58 3E4K
060463 - Kaiser x 081108, ref SDS 57 UZ7K
060464 - Kaiser x 081107, ref SDS 56 UZ7K
060465 - Lafayette 5.50 90.2 120 143 081025, ref SDS 54 3E4K
060466 - Kaiser x 081025, ref SDS 54 UZ7K
060467 - Kaiser x 081024, ref SDS 53 UZ7K
060468 - UCSF c 081023, ref SDS 52 V94O
060469 - Lafayette 5.50 90.6 115 141 081021, ref SDS 51 3E4K
060470 - Lafayette 5.50 90.4 110 128 081020, ref SDS 50 3E4K
060471 - Kaiser x 081018, ref SDS 49 UZ7K
060472 - Kaiser x 081017, ref SDS 48 UZ7K
060473 - UCSF e 081016, ref SDS 46 V94O,
060474 - Lafayette 5.50 90.1 115 154 081014, ref SDS 45 3E4K
060475 - Lafayette 5.50 92.7 115 138 081013, ref SDS 44 3E4K
060476 - Lafayette 8.25 146.4 180 224 081012, ref SDS 43 3E4K
060477 - Kaiser x 081011, ref SDS 42 UZ7K
060478 - Lafayette 5.50 93.3 116 138 081010, ref SDS 41 3E4K
060479 - Kaiser x 081010, ref SDS 41 UZ7K
060480 - UCSF e 081009, ref SDS 40 V94O
060481 - Lafayette 5.50 92.1 113 137 081006, ref SDS 39 3E4K
060482 - Lafayette 2.75 48.5 110 136 x 081004, ref SDS 38 3E4K
060483 - Lafayette 5.50 98.2 117 136 x 081003, ref SDS 37 3E4K
060484 - UCSF c 081002, ref SDS 36 V94O
060485 - Lafayette 5.50 94.7 115 142 080929, ref SDS 35 3E4K
060486 - Lafayette 8.25 150.4 115 135 080928, ref SDS 35 3E4K
060487 - Kaiser x 080927, ref SDS 34 UZ7K
060488 - Lafayette 5.50 90.2 120 140 x 080926, ref SDS 33 3E4K
060489 - UCSF c 080925, ref SDS 32 V94O
060490 - Lafayette 5.50 92.3 116 138 080923, ref SDS 31 3E4K
060491 - Lafayette 5.50 98.4 112 134 080922, ref SDS 31 3E4K
060492 - Lafayette 5.50 98.2 114 137 080921, ref SDS 31 3E4K
060493 - Lafayette 5.50 101.6 110 133 x 080920, ref SDS 30 3E4K
060494 - Lafayette 5.50 89.3 115 144 x 080919, ref SDS 29 3E4K
060495 - UCSF c 080918, ref SDS 28 V94O
060496 - Lafayette 2.75 46.2 117 139 080916, ref SDS 29 3E4K
060497 - Lafayette 5.50 91.8 117 142 080915, ref SDS 27 3E4K
060498 - Clayton Safeway 3.00 62.4 98 118 080914, ref SDS 26 3E4K
060499 - Lafayette 8.25 129.7 123 147 x 080913, ref SDS 25 3E4K
060500 - Lafayette 5.50 88.4 118 146 x 080912, ref SDS 24 3E4K
060501 - UCSF c 080911, ref SDS 23 V94O
060502 - Lafayette 2.75 46.8 113 140 080909
060503 - Lafayette 5.50 89.2 117 143 080908
060504 - Lafayette 5.50 92.1 115 138 080907
060505 - Lafayette 2.75 45.3 120 144 x 080906, ref SDS 22 3E4K
060506 - Lafayette 2.75 56.8 93 120 x 080905, ref SDS 21 3E4K
060507 - UCSF c 080904, ref SDS 20 V94O
060508 - Lafayette 8.25 140.4 116 131 080903
060509 - Lafayette 5.50 94.9 115 134 080902
060510 - Kaiser x 080830
060511 - Kaiser x 080829
060512 - UCSF c 080828, ref SDS 19 V94O
060513 - Lafayette 5.50 93.6 120 137 080826
060514 - Lafayette 5.50 93.2 117 138 080825
060515 - Lafayette 5.50 93.2 123 136 x 080823
060516 - Lafayette 8.25 142.5 110 131 x 080822, ref SDS 18 3E4K
060517 - UCSF e 080821, ref SDS 17 V94O
060518 - Lafayette 5.50 94.7 115 137 080820
060519 - Lafayette 5.50 94.3 115 135 080819
060520 - Lafayette 8.25 141.7 118 134 080815
060521 - UCSF e 080814, ref SDS 16 V94O
060522 - Lafayette 5.50 93.8 120 136 080813
060523 - Lafayette 5.50 94.4 116 139 080812
060524 - Lafayette 5.50 94.2 119 133 080810
060525 - Lafayette 8.25 143.6 114 132 x 080809, ref SDS 14 3E4K
060526 - Lafayette 8.25 141.1 117 135 x 080808, ref SDS 13 3E4K
060527 - UCSF c 080807, ref SDS 12 V94O
060528 - Lafayette 8.25 143.7 115 132 080805
060529 - Concord 7.00 127.6 105 118 080804
060530 - Lafayette 8.25 143.2 112 134 080802
060531 - Lafayette 5.50 93.4 115 138 080801
060532 - Lafayette 5.50 92.2 118 140 080729
060533 - Lafayette 5.50 92.6 116 137 080728
060534 - Lafayette 8.25 142.6 114 134 080727
060535 - Lafayette 5.50 91.5 120 143 080726
060536 - Lafayette 8.25 140.8 117 135 080725
060537 - Lafayette 5.50 91.8 122 141 080723
060538 - Lafayette 5.50 91.3 120 139 080722
060539 - Lafayette 8.25 143.3 115 133 080720
060540 - Lafayette 5.50 90.7 125 144 080719
060541 - Lafayette 5.50 92.4 123 142 080716
060542 - Lafayette 2.25 46.8 116 137 080715
060543 - Lafayette 8.25 141.8 116 136 080712
060544 - Lafayette 5.50 92.9 116 139 080711
060545 - Lafayette 8.25 143.3 113 137 080704
060546 - Lafayette 5.50 90.2 121 147 080630
060547 - Lafayette 8.25 142.4 116 138 080628
060548 - Lafayette 5.50 91.4 118 138 080625
060549 - Lafayette 2.25 47.9 116 136 080623
060550 - Lafayette 5.50 94.2 112 138 080622
060551 - Lafayette 5.50 94.7 115 133 080621
060552 - Lafayette 2.25 48.3 110 129 080620
060553 - Mt Diablo 7.00 129.4 130 153 080616
060554 - Lafayette 5.50 90.8 120 146 080615
060555 - Lafayette 5.50 91.3 124 144 080614
060556 - Lafayette 5.50 89.7 122 143 080613
060557 - Lafayette 2.76 45.8 120 147 080611
060558 - Lafayette 5.50 90.5 123 145 080609
060559 - Lafayette 5.50 92.7 115 138 080607
060560 - Lafayette 5.50 94.2 118 139 080602
060561 - Lafayette 5.50 96.2 110 202 080507, ref SDS 3 WO8M
060562 -
060563 -
060564 -
0606 -
SUBJECTS
Default Null Subject Account for Blank Record
0703 -
070401 - ..
070402 - Side Effects Neupogen Treatments Increase May Be Chemotherapy
070403 -
070404 - Follow up ref SDS 68 SB8I. ref SDS 65 SB8I.
070405 -
070406 - Research on Neupogen side effects was reported on 080629. ref SDS 7
070407 - RQ9I Previous case study on Neupogen side effects listed on 081002.
070408 - ref SDS 33 SB8I
070410 - ..
070411 - Millie last reported side effects of Neupogen on 081109 experiencing
070412 - bone pain, headache, and fatigue associated with Neupogen and
070413 - chemotherapy. ref SDS 58 9V4H
070415 - ..
070416 - Millie may not need Neupogen for the sunitinib treatment begun on
070417 - 081114. ref SDS 61 505G
070419 - ..
070420 - She cancelled treatment on 081114 and 081115.
070422 - ..
070423 - Side effects of Neupogen should cease, because she has not had a
070424 - treatment since 081108, ref SDS 57 UZ7K, citing background for getting
070425 - Neupogen treatment reported in the record on 081107. ref SDS 56 1M9O
070426 -
070427 - 081109................, ref SDS 58 SB8I
070428 - 081018................, ref SDS 49 Y17L
070429 - 081011................, ref SDS 42 FL4H
070430 - 081010................, ref SDS 41 SB8I
070431 - 081006................, ref SDS 39 3E4K
070432 - 081004................, ref SDS 38 Y17L
070433 - 081002................, ref SDS 36 Y17L
070434 - 080930................, ref SDS 35 Y17L
070435 - 080923................, ref SDS 31 K16F
070436 - 080915................, ref SDS 27 9W9I
070437 - 080810................, ref SDS 15 9W9I
070438 - 080803................, ref SDS 11 9W9I
070439 - 080726................, ref SDS 10 9W9I
070440 - 080721................, ref SDS 9 9W9I
070441 - 080713................, ref SDS 8 RM94
070442 - 080629................, ref SDS 6 6Q5J
070443 - 080628................, ref SDS 5 6Q5J
070444 -
070445 -
070446 -
070447 -
070448 -
070449 -
070450 -
070451 -
0705 -