THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: October 25, 2008 09:00 AM Saturday; Rod Welch

Millie 2nd Neupgogen at Kaiser for 2nd cancer treatment 9th cycle UCSF

1...Summary/Objective
2...Neupogen Treatment at Kaiser Prescribed at UCSF for Clinical Trial
3...Schedule Neupogen Treatments Extended through August
4...Exercise Hiking Maintain Fitness Strengthen Immune System
5...Side Effects Neupogen Treatments Increase May Be Chemotherapy


..............
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CONTACTS 

SUBJECTS
Neupogen Side Effects Bone Pain Fatigue No Headache Suffered Today A

1503 -
1503 -    ..
1504 - Summary/Objective
1505 -
150501 - Follow up ref SDS A6 0000. ref SDS A2 0000.
150502 -
150503 -
150504 -
150505 -
150507 -  ..
1506 -
1507 -
1508 - Progress
1509 -
150901 - Neupogen Treatment at Kaiser Prescribed at UCSF for Clinical Trial
150902 -
150903 - Follow up ref SDS A6 9W9I, ref SDS A2 9W9I.
150904 -
150905 - Background on missing treatment at UCSF due to low blood counts, and
150906 - requirements for Neupogen are reported in the record on 081016.
150907 - ref SDS 99 OK67
150909 -  ..
150910 - Case study on 060809 shows Millie has often received chemotherapy when
150911 - blood counts are below the standard for safe treatments, and on some
150912 - occassions has received Neupogen to increase blood counts. ref SDS 9
150913 - HV45
150915 -  ..
150916 - Research on neutropenia was reported on 070301, ref SDS 10 O59H, when
150917 - Doctor Rugo was concerned about holding blood counts with weekly
150918 - Carboplatin treatments. ref SDS 10 VF6O
150920 -  ..
150921 - Anne was Millie's nurse today.  She gave Millie 2 injections required
150922 - for the 2nd Neupogen treatment prescribed this week...
150923 -
150924 -            Neupogen 480 mcg SQ on D2 3 3 carbo
150925 -
150926 - ...as shown in UCSF Chemotherapy Order on 080918, ref SDS 82 PWSY, and
150927 - ordered by primary care physician at Kaiser on 080609. ref SDS 38 L16I
150929 -  ..
150930 - Prior instructions describe Kaiser protocol calls for 480 mcg be given
150931 - with 2 injections, discussed on 080801 ref SDS 58 9W9I, and originally
150932 - presented by Laura on 080628. ref SDS 43 Q74G
150933 -
150934 -
150935 -
150936 -
1510 -

SUBJECTS
Default Null Subject Account for Blank Record

1603 -
160401 -  ..
160402 - Schedule Neupogen Treatments Extended through August
160403 -
160404 - Follow up ref SDS A6 WJ4O, ref SDS A2 WJ4O.
160405 -
160406 - Millie's schedule for was last updated on 081018. ref SDS A2 WJ4O
160407 -
160408 -
160409 -
1605 -

SUBJECTS
Default Null Subject Account for Blank Record

1703 -
170401 -  ..
170402 - Exercise Hiking Maintain Fitness Strengthen Immune System
170403 -
170404 - Follow up ref SDS A6 3E4K, ref SDS A4 3E4K.
170405 -
170406 - Millie went hiking at Lafayette reservoir and did 2 laps, about 5.50
170407 - miles.  Time was again very good, 90.2 minutes, similar to 081021 when
170408 - she did a double in the gym and hiking. ref SDS A4 3E4K  Today, the
170409 - 2nd lap was less than 44 minutes, so this was pushing it.
170411 -  ..
170412 - Maximum pulse elevated to 143 on the 2nd lap going up the big long
170413 - hill, because Millie increased speed.  It dropped into the 120s, then
170414 - went back up on the longer, but less steep last hill to again about
170415 - 141, and then settled again bact in the 120s.  Normally, Millie's
170416 - pulse will settle back to below 110.  Today she hiked faster.
170418 -  ..
170419 - Hiking will be reduced this coming week, because of meetings getting
170420 - setu for changing treatments.  Millie is vacation for the next two
170421 - weeks.
170422 -
170423 -                                              +- c = Carboplatin
170424 -                                              +- e = Erbatex cetuximab
170425 -                           Time     Pulse     |
170426 -    Location        Miles Minutes  Avg Max  Chem Neupo  Date
170427 -    ----------------------------------------------------------------
170428 -    Lafayette        5.50   90.2   120 143              081025, ref SDS 0 3E4K
170429 -    Kaiser                                         x    081025, ref SDS 0 UZ7K
170430 -    Kaiser                                         x    081024, ref SDS A6 UZ7K
170431 -    UCSF                                     c          081023, ref SDS A5 V94O
170432 -    Lafayette        5.50   90.6   115 141              081021, ref SDS A4 3E4K
170433 -    Lafayette        5.50   90.4   110 128              081020, ref SDS A3 3E4K
170434 -    Kaiser                                         x    081018, ref SDS A2 UZ7K
170435 -    Kaiser                                         x    081017, ref SDS A1 UZ7K
170436 -    UCSF                                     e          081016, ref SDS 99 V94O,
170437 -    Lafayette        5.50   90.1   115 154              081014, ref SDS 98 3E4K
170438 -    Lafayette        5.50   92.7   115 138              081013, ref SDS 97 3E4K
170439 -    Lafayette        8.25  146.4   180 224              081012, ref SDS 96 3E4K
170440 -    Kaiser                                         x    081011, ref SDS 95 UZ7K
170441 -    Lafayette        5.50   93.3   116 138              081010, ref SDS 94 3E4K
170442 -    Kaiser                                         x    081010, ref SDS 94 UZ7K
170443 -    UCSF                                      e         081009, ref SDS 93 V94O
170444 -    Lafayette        5.50   92.1   113 137              081006, ref SDS 92 3E4K
170445 -    Lafayette        2.75   48.5   110 136         x    081004, ref SDS 91 3E4K
170446 -    Lafayette        5.50   98.2   117 136         x    081003, ref SDS 90 3E4K
170447 -    UCSF                                      c         081002, ref SDS 89 V94O
170448 -    Lafayette        5.50   94.7   115 142              080929, ref SDS 88 3E4K
170449 -    Lafayette        8.25  150.4   115 135              080928, ref SDS 88 3E4K
170450 -    Kaiser                                         x    080927, ref SDS 87 UZ7K
170451 -    Lafayette        5.50   90.2   120 140         x    080926, ref SDS 86 3E4K
170452 -    UCSF                                      c         080925, ref SDS 85 V94O
170453 -    Lafayette        5.50   92.3   116 138              080923, ref SDS 84 3E4K
170454 -    Lafayette        5.50   98.4   112 134              080922, ref SDS 84 3E4K
170455 -    Lafayette        5.50   98.2   114 137              080921, ref SDS 84 3E4K
170456 -    Lafayette        5.50  101.6   110 133         x    080920, ref SDS 83 3E4K
170457 -    Lafayette        5.50   89.3   115 144         x    080919, ref SDS 82 3E4K
170458 -    UCSF                                      c         080918, ref SDS 81 V94O
170459 -    Lafayette        2.75   46.2   117 139              080916, ref SDS 82 3E4K
170460 -    Lafayette        5.50   91.8   117 142              080915, ref SDS 80 3E4K
170461 -    Clayton Safeway  3.00   62.4    98 118              080914, ref SDS 79 3E4K
170462 -    Lafayette        8.25  129.7   123 147         x    080913, ref SDS 78 3E4K
170463 -    Lafayette        5.50   88.4   118 146         x    080912, ref SDS 77 3E4K
170464 -    UCSF                                      c         080911, ref SDS 76 V94O
170465 -    Lafayette        2.75   46.8   113 140              080909
170466 -    Lafayette        5.50   89.2   117 143              080908
170467 -    Lafayette        5.50   92.1   115 138              080907
170468 -    Lafayette        2.75   45.3   120 144         x    080906, ref SDS 75 3E4K
170469 -    Lafayette        2.75   56.8    93 120         x    080905, ref SDS 74 3E4K
170470 -    UCSF                                      c         080904, ref SDS 73 V94O
170471 -    Lafayette        8.25  140.4   116 131              080903
170472 -    Lafayette        5.50   94.9   115 134              080902
170473 -    Kaiser                                         x    080830
170474 -    Kaiser                                         x    080829
170475 -    UCSF                                      c         080828, ref SDS 70 V94O
170476 -    Lafayette        5.50   93.6   120 137              080826
170477 -    Lafayette        5.50   93.2   117 138              080825
170478 -    Lafayette        5.50   93.2   123 136         x    080823
170479 -    Lafayette        8.25  142.5   110 131         x    080822, ref SDS 68 3E4K
170480 -    UCSF                                      e         080821, ref SDS 67 V94O
170481 -    Lafayette        5.50   94.7   115 137              080820
170482 -    Lafayette        5.50   94.3   115 135              080819
170483 -    Lafayette        8.25  141.7   118 134              080815
170484 -    UCSF                                      e         080814, ref SDS 65 V94O
170485 -    Lafayette        5.50   93.8   120 136              080813
170486 -    Lafayette        5.50   94.4   116 139              080812
170487 -    Lafayette        5.50   94.2   119 133              080810
170488 -    Lafayette        8.25  143.6   114 132         x    080809, ref SDS 62 3E4K
170489 -    Lafayette        8.25  141.1   117 135         x    080808, ref SDS 61 3E4K
170490 -    UCSF                                      c         080807, ref SDS 60 V94O
170491 -    Lafayette        8.25  143.7   115 132              080805
170492 -    Concord          7.00  127.6   105 118              080804
170493 -    Lafayette        8.25  143.2   112 134              080802
170494 -    Lafayette        5.50   93.4   115 138              080801
170495 -    Lafayette        5.50   92.2   118 140              080729
170496 -    Lafayette        5.50   92.6   116 137              080728
170497 -    Lafayette        8.25  142.6   114 134              080727
170498 -    Lafayette        5.50   91.5   120 143              080726
170499 -    Lafayette        8.25  140.8   117 135              080725
170500 -    Lafayette        5.50   91.8   122 141              080723
170501 -    Lafayette        5.50   91.3   120 139              080722
170502 -    Lafayette        8.25  143.3   115 133              080720
170503 -    Lafayette        5.50   90.7   125 144              080719
170504 -    Lafayette        5.50   92.4   123 142              080716
170505 -    Lafayette        2.25   46.8   116 137              080715
170506 -    Lafayette        8.25  141.8   116 136              080712
170507 -    Lafayette        5.50   92.9   116 139              080711
170508 -    Lafayette        8.25  143.3   113 137              080704
170509 -    Lafayette        5.50   90.2   121 147              080630
170510 -    Lafayette        8.25  142.4   116 138              080628
170511 -    Lafayette        5.50   91.4   118 138              080625
170512 -    Lafayette        2.25   47.9   116 136              080623
170513 -    Lafayette        5.50   94.2   112 138              080622
170514 -    Lafayette        5.50   94.7   115 133              080621
170515 -    Lafayette        2.25   48.3   110 129              080620
170516 -    Mt Diablo        7.00  129.4   130 153              080616
170517 -    Lafayette        5.50   90.8   120 146              080615
170518 -    Lafayette        5.50   91.3   124 144              080614
170519 -    Lafayette        5.50   89.7   122 143              080613
170520 -    Lafayette        2.76   45.8   120 147              080611
170521 -    Lafayette        5.50   90.5   123 145              080609
170522 -    Lafayette        5.50   92.7   115 138              080607
170523 -    Lafayette        5.50   94.2   118 139              080602
170524 -    Lafayette        5.50   96.2   110 202              080507, ref SDS 30 WO8M
170525 -
170526 -
170527 -
170528 -
1706 -

SUBJECTS
Default Null Subject Account for Blank Record

1803 -
180401 -  ..
180402 - Side Effects Neupogen Treatments Increase May Be Chemotherapy
180403 -
180404 - Follow up ref SDS A6 SB8I, ref SDS A2 SB8I.
180405 -
180406 - Research on Neupogen side effects was reported on 080629. ref SDS 44
180407 - RQ9I  Previous case study on Neupogen side effects listed on 081002.
180408 - ref SDS 86 SB8I
180410 -  ..
180411 - She had a long day, going to Kaiser for Neupogen, then to a meeting
180412 - for a biopsy that turned out to be deferred. ref SDS A7 G15K  She then
180413 - had a meeting with the primary care physician to review planning at
180414 - UCSF for starting a new treatment to recover from the 5th relapse of
180415 - IBC. ref SDS A8 0001  There were then extended discussions with the
180416 - CT department about doing a test using the Power Port.
180418 -  ..
180419 - Despite all of this emotional activity, Millie did not complain of
180420 - specific bone pain, fatigue, nor headache, which are side effects of
180421 - chemotherapy.
180423 -  ..
180424 - Millie last reported side effects on 081018 experiencing bone pain,
180425 - headache, and fatigue associated with Neupogen and chemotherapy.
180426 - ref SDS A2 Y17L
180428 -  ..
180429 - Side effects of Neupogen may be increasing, reported on...
180430 -
180431 -               081018................, ref SDS A2 Y17L
180432 -               081011................, ref SDS 95 FL4H
180433 -               081010................, ref SDS 94 SB8I
180434 -               081006................, ref SDS 92 3E4K
180435 -               081004................, ref SDS 91 Y17L
180436 -               081002................, ref SDS 89 Y17L
180437 -               080930................, ref SDS 88 Y17L
180438 -               080923................, ref SDS 84 K16F
180439 -               080915................, ref SDS 80 9W9I
180440 -               080810................, ref SDS 63 9W9I
180441 -               080803................, ref SDS 59 9W9I
180442 -               080726................, ref SDS 56 9W9I
180443 -               080721................, ref SDS 54 9W9I
180444 -               080713................, ref SDS 48 RM94
180445 -               080629................, ref SDS 43 6Q5J
180446 -               080628................, ref SDS 41 6Q5J
180447 -
180448 -
180449 -
180450 -
180451 -
180452 -
180453 -
1805 -