THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: October 4, 2008 09:00 AM Saturday; Rod Welch

Millie 2nd Neupgogen at Kaiser for 3rd cancer treatment 8th cycle UCSF

1...Summary/Objective
2...Neupogen Treatment at Kaiser Prescribed at UCSF for Clinical Trial
3...Schedule Neupogen Treatments Extended through August
4...Exercise Hiking Maintain Fitness Strengthen Immune System
5...Side Effects Neupogen Treatments Increase May Be Chemotherapy


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CONTACTS 

SUBJECTS
Neupogen Side Effects Bone Pain Fatigue No Headache Suffered Today A

1503 -
1503 -    ..
1504 - Summary/Objective
1505 -
150501 - Follow up ref SDS 88 0000. ref SDS 85 0000.
150502 -
150503 -
150504 -
150505 -
150506 -
150508 -  ..
1506 -
1507 -
1508 - Progress
1509 -
150901 - Neupogen Treatment at Kaiser Prescribed at UCSF for Clinical Trial
150902 -
150903 - Follow up ref SDS 88 9W9I, ref SDS 85 9W9I.
150904 -
150905 - Background on missing treatment at UCSF due to low blood counts, and
150906 - requirements for Neupogen are reported in the record on 080821.
150907 - ref SDS 64 ON5M   Case study on neutropenia reported in the record for
150908 - 080828 shows continuing need for Neupogen. ref SDS 68 8O7I
150910 -  ..
150911 - Nadine was Millie's nurse today.  She gave Millie 1 injection required
150912 - for prescription of treatment...
150913 -
150914 -            Neupogen 480 mcg SQ on D2 3 3 carbo
150915 -
150916 - ...as shown in UCSF Chemotherapy Order on 080918, ref SDS 79 PWSY, and
150917 - ordered by primary care physician at Kaiser on 080609. ref SDS 35 L16I
150919 -  ..
150920 - Prior instructions describe Kaiser protocol calls for 480 mcg be given
150921 - with 2 injections, discussed on 080801 ref SDS 55 9W9I, and originally
150922 - presented by Laura on 080628. ref SDS 40 Q74G
150923 -
150924 -
150925 -
150926 -
1510 -

SUBJECTS
Default Null Subject Account for Blank Record

1603 -
160401 -  ..
160402 - Schedule Neupogen Treatments Extended through August
160403 -
160404 - Follow up ref SDS 88 WJ4O, ref SDS 85 WJ4O.
160405 -
160406 - Millie's schedule for Neupogen was last updated on 080920. ref SDS 81
160407 - SY8G
160409 -             ..
160410 -            [On 081018 Millie's schedule was next updated. ref SDS 89
160411 -            WJ4O
160413 -  ..
160414 - Bella was on staff today.  She updated the Neupogen schedule for
160415 - November...
160416 -
160417 -                                                        UCSF Chemo
160418 -        Date    Time   Provider         Services      Cycle Treatmnt
160419 -        080926  1430   Infusion Nurse   Neupogen        8     2
160420 -        080927  0900   Infusion Nurse   Neupogen        8     2
160421 -        081003  1400   Infusion Nurse   Neupogen        8     3
160422 -        081004  0900   Infusion Nurse   Neupogen        8     3
160423 -        081010  1400   Infusion Nurse   Neupogen        8     4
160424 -        081011  0900   Infusion Nurse   Neupogen        8     4
160425 -        081017  1400   Infusion Nurse   Neupogen        9     1
160426 -        081018  0900   Infusion Nurse   Neupogen        9     1
160427 -        081024  1230   Infusion Nurse   Neupogen        9     2
160428 -        081025  0900   Infusion Nurse   Neupogen        9     2
160429 -        081031     Millie on vacation                   9     3
160430 -        081101     Millie on vacation                   9     3
160431 -        081108  1400   Infusion Nurse   Neupogen        9     4
160432 -         ..
160433 -        081110  0830   Infusion Nurse   Neupogen        9     4
160434 -        081114  1300   Infusion Nurse   Neupogen       10     1
160435 -        081115  0830   Infusion Nurse   Neupogen       10     1
160436 -        081121  1300   Infusion Nurse   Neupogen       10     2
160437 -        081122  0830   Infusion Nurse   Neupogen       10     2
160438 -         ..
160439 -     *  081128  0830   Infusion Nurse   Neupogen       10     3
160440 -        081129  0830   Infusion Nurse   Neupogen       10     3
160442 -            ..
160443 -        *  0830 on Friday 081128 is okay because Millie gets
160444 -           chemotherapy treatment at UCSF on Wednesday, 081126, because
160445 -           Thanskgiving is on 081127.  This complies with requirements
160446 -           for Neupogen 24 hours after chemotherapy, reported by Doctor
160447 -           Rugo at UCSF on 080821. ref SDS 64 4B4L
160448 -
160449 -
1605 -

SUBJECTS
Default Null Subject Account for Blank Record

1703 -
170401 -  ..
170402 - Exercise Hiking Maintain Fitness Strengthen Immune System
170403 -
170404 - Follow up ref SDS 88 3E4K, ref SDS 85 3E4K.
170405 -
170406 - Today, Millie went hiking and did only 1 lap.  Went a little slow so
170407 - the patient assistant would not reinjure the hamstring again.
170409 -  ..
170410 - Hiking was less steady last week, going out 4 days, but generally
170411 - continuing increased exercise...
170412 -
170413 -    Location             Miles  Minutes  Chemo  Neupo   Date
170414 -    ----------------------------------------------------------------
170415 -    Lafayette             2.75    48.5             x    081004, ref SDS 0 3E4K
170416 -    Lafayette             5.50    98.2             x    081003, ref SDS 88 3E4K
170417 -    UCSF                                     c          081002, ref SDS 87 V94O
170418 -    Lafayette             5.50    94.7                  080929, ref SDS 86 3E4K
170419 -    Lafayette             8.25   150.4                  080928, ref SDS 86 3E4K
170420 -    Kaiser                                         x    080927, ref SDS 85 UZ7K
170421 -    Lafayette       *     5.50    90.2             x    080926, ref SDS 84 3E4K
170422 -    UCSF                                     c          080925, ref SDS 83 V94O
170423 -    Lafayette             5.50    92.3                  080923, ref SDS 82 3E4K
170424 -    Lafayette             5.50    98.4                  080922, ref SDS 82 3E4K
170425 -    Lafayette             5.50    98.2                  080921, ref SDS 82 3E4K
170426 -    Lafayette             5.50   101.6             x    080920, ref SDS 81 3E4K
170427 -    Lafayette             5.50    89.3             x    080919, ref SDS 80 3E4K
170428 -    UCSF                                     c          080918, ref SDS 79 V94O
170429 -    Lafayette             2.75    46.2                  080916, ref SDS 80 3E4K
170430 -    Lafayette             5.50    91.8                  080915, ref SDS 78 3E4K
170431 -    Clayton Safeway       3.00    62.4                  080914, ref SDS 77 3E4K
170432 -    Lafayette             8.25   129.7             x    080913, ref SDS 76 3E4K
170433 -    Lafayette             5.50    88.4             x    080912, ref SDS 75 3E4K
170434 -    UCSF                                     c          080911, ref SDS 74 V94O
170435 -    Lafayette             2.75    46.8                  080909
170436 -    Lafayette             5.50    89.2                  080908
170437 -    Lafayette             5.50    92.1                  080907
170438 -    Lafayette             2.75    45.3             x    080906, ref SDS 73 3E4K
170439 -    Lafayette             2.75    56.8             x    080905, ref SDS 72 3E4K
170440 -    UCSF                                     c          080904, ref SDS 71 V94O
170441 -    Lafayette             8.25   140.4                  080903
170442 -    Lafayette             5.50    94.9                  080902
170443 -    Kaiser                                         x    080830
170444 -    Kaiser                                         x    080829
170445 -    UCSF                                     c          080828, ref SDS 68 V94O
170446 -    Lafayette             5.50    93.6                  080826
170447 -    Lafayette             5.50    93.2                  080825
170448 -    Lafayette             5.50    93.2             x    080823
170449 -    Lafayette             8.25   142.5             x    080822, ref SDS 66 3E4K
170450 -    UCSF                                     e          080821, ref SDS 65 V94O
170451 -    Lafayette             5.50    94.7                  080820
170452 -    Lafayette             5.50    94.3                  080819
170453 -    Lafayette             8.25   141.7                  080815
170454 -    UCSF                                     e          080814, ref SDS 63 V94O
170455 -    Lafayette             5.50    93.8                  080813
170456 -    Lafayette             5.50    94.4                  080812
170457 -    Lafayette             5.50    94.2                  080810
170458 -    Lafayette             8.25   143.6             x    080809, ref SDS 60 3E4K
170459 -    Lafayette             8.25   141.1             x    080808, ref SDS 59 3E4K
170460 -    UCSF                                     c          080807, ref SDS 58 V94O
170461 -    Lafayette             8.25   143.7                  080805
170462 -    Concord               7.00   127.6                  080804
170463 -    Lafayette             8.25   143.2                  080802
170464 -    Lafayette             5.50    93.4                  080801
170465 -    Lafayette             5.50    92.2                  080729
170466 -    Lafayette             5.50    92.6                  080728
170467 -    Lafayette             8.25   142.6                  080727
170468 -    Lafayette             5.50    91.5                  080726
170469 -    Lafayette             8.25   140.8                  080725
170470 -    Lafayette             5.50    91.8                  080723
170471 -    Lafayette             5.50    91.3                  080722
170472 -    Lafayette             8.25   143.3                  080720
170473 -    Lafayette             5.50    90.7                  080719
170474 -    Lafayette             5.50    92.4                  080716
170475 -    Lafayette             2.25    46.8                  080715
170476 -    Lafayette             8.25   141.8                  080712
170477 -    Lafayette             5.50    92.9                  080711
170478 -    Lafayette             8.25   143.3                  080704
170479 -    Lafayette             5.50    90.2                  080630
170480 -    Lafayette             8.25   142.4                  080628
170481 -    Lafayette             5.50    91.4                  080625
170482 -    Lafayette             2.25    47.9                  080623
170483 -    Lafayette             5.50    94.2                  080622
170484 -    Lafayette             5.50    94.7                  080621
170485 -    Lafayette             2.25    48.3                  080620
170486 -    Mt Diablo             7.00   129.4                  080616
170487 -    Lafayette             5.50    90.8                  080615
170488 -    Lafayette             5.50    91.3                  080614
170489 -    Lafayette             5.50    89.7                  080613
170490 -    Lafayette             2.76    45.8                  080611
170491 -    Lafayette             5.50    90.5                  080609
170492 -    Lafayette             5.50    92.7                  080607
170493 -    Lafayette             5.50    94.2                  080602
170494 -
170495 -
170496 -
1705 -

SUBJECTS
Default Null Subject Account for Blank Record

1803 -
180401 -  ..
180402 - Side Effects Neupogen Treatments Increase May Be Chemotherapy
180403 -
180404 - Follow up ref SDS 87 SB8I, ref SDS 79 SB8I.
180405 -
180406 - Research on Neupogen side effects was reported on 080629. ref SDS 41
180407 - RQ9I  Previous case study on Neupogen side effects listed on 081002.
180408 - ref SDS 83 SB8I
180410 -  ..
180411 - Millie previously reported Neupogen side effects on 080927, as shown
180412 - on 080930. ref SDS 86 Y17L
180414 -  ..
180415 - Millie did not feel well today.  She planned going to the movies, but
180416 - after the hike and having some lunch, she layed down for 3 or so
180417 - hours.  She had a good breakfast/lunch after the hike, about 1100.
180418 - Had very little to eat for dinner, maybe 2 or 3 bites.  She complained
180419 - about not feeling well about 1800.  Millie was asleep again by 1930.
180421 -  ..
180422 - She has no temperature.
180424 -  ..
180425 - Complains of headache, but not bone pain.  Millie did not take aspirin
180426 - or other medication to relieve headache.
180428 -  ..
180429 - Both are symptoms of Neupogen side effects, reported in research on
180430 - 080629. ref SDS 41 TR5L
180432 -  ..
180433 - She just feels "lousy" today, which also fits side effects of
180434 - chemotherapy.  If so, this is the first serious episode after 19
180435 - treatments of Carboplatin, beginning on 080313, reported on 081002.
180436 - ref SDS 87 5B6J  There may also be a cumulative effect of 87
180437 - treatments with cetuximab, beginning on 070201.
180439 -  ..
180440 - Side effects of Neupogen may be increasing, reported on...
180441 -
180442 -               081002................, ref SDS 87 Y17L
180443 -               080930................, ref SDS 86 Y17L
180444 -               080923................, ref SDS 82 K16F
180445 -               080915................, ref SDS 78 9W9I
180446 -               080810................, ref SDS 61 9W9I
180447 -               080803................, ref SDS 57 9W9I
180448 -               080726................, ref SDS 54 9W9I
180449 -               080721................, ref SDS 52 9W9I
180450 -               080713................, ref SDS 46 RM94
180451 -               080629................, ref SDS 41 6Q5J
180452 -               080628................, ref SDS 39 6Q5J
180453 -
180454 -
180455 -
180456 -
180457 -
180458 -
180459 -
180460 -
180461 -
1805 -