THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: June 28, 2008 08:17 AM Saturday; Rod Welch

Millie reports side effects from Neupogen headaches, bone pain.

1...Summary/Objective


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CONTACTS 

SUBJECTS
Headaches Ill Feeling Bone Pain Again Day After 2nd Neupogen Treatme

1803 -
1803 -    ..
1804 - Summary/Objective
1805 -
180501 - Follow up ref SDS 10 0000, ref SDS 9 0000.
180502 -
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180504 -
180505 -
180507 -  ..
1806 -
1807 -
1808 - Progress
1809 -
180901 - Millie has a headache this morning, and does not feel well.  She also
180902 - complained of bone pain.  It is hard to remember Millie ever having
180903 - reported a headache.
180905 -  ..
180906 - The only previous report of bone pain was on 080409 when Millie came
180907 - home with Cellulitis recurrence, ref SDS 3 V45J, and had to get
180908 - treatment in the Emergency clinic at Kaiser. ref SDS 3 0R4H  At that
180909 - time, bone pain was associated with Cellulitis, however, Millie was
180910 - also getting Neupogen treatments for the first time, since starting
180911 - treatment in the clinical trial at UCSF on 070201.   On 080403 UCSF
180912 - prescribed Neupogen. ref SDS 1 6Y9K  Millie took the first Neupogen
180913 - treatment on 080405, ref SDS 2 XQ6O, 4 days before the report of bone
180914 - pain.
180916 -  ..
180917 - Subsequently, Millie has been treated regularly with Neupogen, varying
180918 - from 1 - 2 treatments per week for 1 - 3 weeks per 4 week cycle.
180920 -             ..
180921 -            [On 080629 Millie suffers continuing bone pain, headaches,
180922 -            and fatigue, ref SDS 12 6Q5J, research indicates these
180923 -            maladies are side effects of Neupogen. ref SDS 12 RQ9I
180925 -             ..
180926 -            [On 080702 Millie notified medical team about on set of
180927 -            side effects from Neupogen treatments prescribed for Millie
180928 -            to get cancer treatments. ref SDS 13 EP4Y
180930 -             ..
180931 -            [On 080710 Neupogen side effects have not recurred since
180932 -            080629. ref SDS 14 SB8I
180934 -             ..
180935 -            [On 080713 Millie reported recurrence of Neupogen side
180936 -            effects. ref SDS 15 RM99
180938 -  ..
180939 - UCSF has managed Millie's Neupogen treatments carefully.  For example,
180940 - on 080501 UCSF initially prescribed 2 Neupogen treatments for the 1st
180941 - week of cycle 3, ref SDS 4 QF3N, but an hour or so later submitted a
180942 - letter changing the prescription to only 1 treatment. ref SDS 4 M658
180943 - Weeks later, starting the 4th cycle on 080529, everyone thought the
180944 - doctor had prescribed only 1 treatment per week, ref SDS 5 TE6N, but a
180945 - week later on 080605 Millie received the Chemotherapy Orders that show
180946 - 2 Neupogen treatments were actually prescribed. ref SDS 6 JN38  As a
180947 - result, the week of 080529 Millie had 1 Neupogen treatment, but the
180948 - next 2 weeks, she had 2 during the 4th cycle.
180950 -  ..
180951 - Yesterday, Millie had the Neupogen treatment at Kaiser, ref SDS 10
180952 - YY5H, which was prescribed at UCSF the day before on 080626.
180953 - ref SDS 8 QJ4H  She feels headaches and bone pain today may be caused
180954 - by Neupogen yesterday, based on remembering explanations of side
180955 - effects by the pharmacist several months ago.
180957 -  ..
180958 - UCSF specified 2 Neupogen treatments this week, indicating on 080626
180959 - intent to replicate the prescription on 080529, ref SDS 5 PWSY,
180961 -  ..
180962 - Despite not feeling well, Millie decided to dress for hiking this
180963 - morning.
180965 -  ..
180966 - We went to Kaiser for Millie's 2nd Neupogen treatment. ref SDS 11 YY5H
180968 -  ..
180969 - After getting the treatment, we went to Lafayette Reservoir.
180971 -  ..
180972 - Mil hiked 3 laps for the first time ever, about 8.25 miles.  This is
180973 - farther than the hike of 7 miles up Mt Diablo to Deer Flat, reported
180974 - on 080616. ref SDS 7 IZ5I  Of course Mt Diablo is a much more
180975 - rigorous climb continuously uphill.  Millie has been doing 2 laps at
180976 - Lafayette Reservoir for about a month, so today decided to try for 3
180977 - laps, even though she was still feeling effects of Neupogen.
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