THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: November 17, 2008 07:00 AM Monday; Rod Welch

Millie treatment #4 IBC 5th relapse sunitinib clinical study.

1...Summary/Objective
........Patient History Sunitinib Loading Dose 14 Days
2...Side Effects Sunitinib Study


..............
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CONTACTS 

SUBJECTS
Default Null Subject Account for Blank Record

0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 6 0000. ref SDS 5 0000.
040502 -
040503 -
040504 -
040506 -  ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - On 081113 Millie received sunitinib drugs from UCSF to treat the 5th
040902 - relapse of IBC.
040904 -  ..
040905 - Millie began the 14 day "charging" treatment on 081114. ref SDS 4 EK7I
040906 - After 14 treatments, if Millie tolerates sunitinib at the prescribed
040907 - dose, then she begins adding 2 chemotherapy drugs once a day for 2
040908 - days a week as prescribed in the treatment protocol, reviewed on
040909 - 081017. ref SDS 1 004O
040911 -  ..
040912 - Millie needs a prescription from UCSF for the chemotherapy drugs prior
040913 - to the meeting at UCSF on 081126, because Kaiser will require time for
040914 - the primary care physician to order the drugs, so Millie can have them
040915 - in time to start treatment on Friday, 081128.  This evening, Mille
040916 - sent a letter notifying the medical team to plan for delivering
040917 - medication with disruption of treatment. ref SDS 8 FQ5I
040918 -
040920 -         ..
040921 -        Patient History Sunitinib Loading Dose 14 Days
040922 -
040923 -        Follow up ref SDS 6 OE6K, ref SDS 5 OE6K.
040924 -
040926 -        Cycle 1
040927 -        Cohort: 3
040929 -   ..
040930 -                             Sunitinib MG      Cyclophos    Metho
040931 -                         Amount  Today   Cum    phamide     trexate
040932 -  Days  Date  Time Cycle 25 12.5 Total  Total   Amnt Total Amnt Total
040933 -  --------------------------------------------------------------------
040934 -  Follow up ref SDS 6 PA8Y.
040935 -
040936 -    1.  081114 0700   1   1   1  37.5    37.5    0     0   0    0
040937 -    2.  081115 0700   1   1   1  37.5    75.0    0     0   0    0
040938 -    3.  081116 0700   1   1   1  37.5   112.5    0     0   0    0
040939 -    4.  081117 0700   1   1   1  37.5   150.0    0     0   0    0
040940 -
040941 -
040942 -
040943 -
0410 -

SUBJECTS
Default Null Subject Account for Blank Record

0503 -
050401 -  ..
050402 - Side Effects Sunitinib Study
050403 -
050404 - Follow up ref SDS 6 LF8M, ref SDS 5 LF8M.
050405 -
050406 - Millie reported no side effects today.
050408 -  ..
050409 - Millie's record of exercising shows correlation between treatments and
050410 - exercise as an indicator of adverse side effects. ref SDS 7 8G5M
050412 -  ..
050413 - Millie also has side effects from Neupogen, reported today.
050414 - ref SDS 7 XQ4L
050416 -     ..
050417 -                                   Date
050418 -    Description Adverse Event   Start  Stop     Medication
050419 -    ---------------------------------------------------------
050420 -    Follow up ref SDS 6 LF8M.
050421 -
050422 -       Diarrhea                    081114 081114   Imodium, ref SDS 4 LF8M
050423 -
050424 -
050425 -
050426 -
050427 -
050428 -
050429 -
050430 -
050431 -
0505 -