THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: December 30, 2008 07:00 AM Tuesday; Rod Welch

Millie sunitinib #40 treatment IBC 5th relapse.

1...Summary/Objective
2...Sunitinib Metronomic Treatment Loading Dose Clinical Study UCSF
3...Sunitinib Cyclophosmaide Methotrexate Patient History
4...Side Effects Sunitinib Study with Cyclophosphamide Methotrexate
5...Exercise Hiking Maintain Fitness Strengthen Immune System
6...Case Study on Pateint History Exercising


..............
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CONTACTS 

SUBJECTS
Default Null Subject Account for Blank Record

0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS G6 0000. ref SDS G5 0000.
040502 -
040503 -
040504 -
040505 -
040506 -
040508 -  ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Sunitinib Metronomic Treatment Loading Dose Clinical Study UCSF
040902 -
040903 - Follow up ref SDS G6 505G, ref SDS G5 505G.
040904 -
040905 - Background pausing treatment on 081219 for a week for Millie's blood
040906 - counts to recover, and resuming on 081226 with sunitinib and
040907 - cyclophosphamide. ref SDS G2 505G
040909 -  ..
040910 - Today, IBC rash and nodules in breastbone seem still about the same as
040911 - on 081227, after subsiding on 081226 from incresses on 081224 and
040912 - 081225. ref SDS G2 124N
040914 -  ..
040915 - Today, Millie still tired from the hike on 081227, ref SDS G6 6E7G;
040916 - she also had a CT test, ref SDS G8 3G5I, and so did not go hiking.
040917 - ref SDS G6 X64F
040919 -  ..
040920 - On 081230 case study dilemma cancer treatments cause low blood counts,
040921 - which prevents getting treatment; not getting treatment incerases
040922 - cancer; UCSF paused treatment for a week and prescribed Neupogen to
040923 - increase blood counts. ref SDS G7 I87N
040925 -  ..
040926 - Millie sent a letter to the medical team today reporting favorable
040927 - blood counts from labs at Kaiser on 081226, ref SDS G3 QY6H, enables
040928 - Millie to get full treatment with sunitinib and cyclophosphamide.
040929 - ref SDS G7 JV5M  She further reported increased energy that enabled
040930 - going hiking, ref SDS G7 4W9S, citing hiking on 081227. ref SDS G4
040931 - 3E4K
040933 -  ..
040934 - NEUTS patient history of neutropenia from chemotherapy everyday with
040935 - cyclophosphamide reported in case study on 081205. ref SDS C5 EC5N
040937 -  ..
040938 - Neupogen treatments on 081219 and 081220 at Kaiser, ref SDS F6 UZ7K,
040939 - help maintain blood counts to strengthen Millie's immunity system,
040940 - shown in the schedule for Neupogen treatments updated on 081220.
040941 - ref SDS F6 HS5M
040942 -
040944 -  ..
040945 - Sunitinib Cyclophosmaide Methotrexate Patient History
040946 -
040947 - Follow up ref SDS G6 OE6K, ref SDS G5 OE6K.
040948 -
040950 -        Cycle 1  begin 081128 after 14 treatmenst sunitinib alone
040951 -        Cohort: 3
040953 -        ..
040954 -                                          Cyclophos  Metho
040955 -                               Sunitinib   phamide   trexate
040956 -       Days  Date  Time  Cycle    37.5       50        5
040957 -       =======================================================
040958 -       Follow up ref SDS G6 PA8Y, ref SDS G5 PA8Y.
040959 -
040960 -        1.  081114 0700  Load    37.5         0         0 ... ref SDS 94 OE6K
040961 -        2.  081115 0700  Load    75.0         0         0 ... ref SDS 95 OE6K
040962 -        3.  081116 0700  Load   112.5         0         0 ... ref SDS 96 OE6K
040963 -        4.  081117 0700  Load   150.0         0         0 ... ref SDS 97 OE6K
040964 -        5.  081118 0700  Load   187.5         0         0 ... ref SDS A0 OE6K
040965 -        6.  081119 0700  Load   225.0         0         0 ... ref SDS A2 OE6K
040966 -        7.  081120 0700  Load   263.5         0         0 ... ref SDS A3 OE6K
040967 -        8.  081121 0700  Load   301.0         0         0 ... ref SDS A4 OE6K
040968 -        9.  081122 0700  Load   338.5         0         0 ... ref SDS A5 OE6K
040969 -       10.  081123 0700  Load   376.0         0         0 ... ref SDS A6 OE6K
040970 -       11.  081124 0700  Load   413.5         0         0 ... ref SDS A7 OE6K
040971 -       12.  081125 0700  Load   451.0         0         0 ... ref SDS A8 OE6K
040972 -             ..
040973 -       13.  081126 0700  Load   488.5         0         0 ... ref SDS A9 OE6K
040974 -             ..
040975 -            081126 0820  NEUTS........1.50................... ref SDS B0 PU6K
040977 -             ..
040978 -       14.  081127 0700  Load   526.0         0         0 ... ref SDS B1 OE6K
040979 -       15.  081128 0700  1  1   563.5   1    50    1    5 ... ref SDS B4 OE6K
040980 -       16.  081129 0700  1  2   601.0   2   100    2   10 ... ref SDS B7 OE6K
040981 -       17.  081130 0700  1  3   638.5   3   150    2   10 ... ref SDS B8 OE6K
040982 -       18.  081201 0700  1  4   676.0   4   200    2   10 ... ref SDS B9 OE6K
040983 -       19.  081202 0700  1  5   713.5   5   250    2   10 ... ref SDS C1 OE6K
040984 -             ..
040985 -       20.  081203 0700  1  6   751.0   6   300    2   10 ... ref SDS C3 OE6K
040986 -
040987 -            081203 0735. NEUTS....... 0.624 ...... .......... ref SDS C2 RN5G
040988 -
040989 -                Rate of change per day = 1500 - 624 = 876 / 7
040990 -
040991 -                                       = 120+ per day
040993 -             ..
040994 -       21.  081204 0700  1  7   788.5   7   350    2   10 ... ref SDS C4 OE6K
040995 -             ..
040996 -       22.  081205 0700  1  8   826.0   8   400    3   15 ... ref SDS C5 OE6K
040997 -
040998 -            081205 1300  Neupogen...... 480 mcg  480......... ref SDS C6 KV84
041000 -             ..
041001 -       23.  081206 0700  1  9   863.5   9   450    4   20 ... ref SDS C9 OE6K
041002 -
041003 -            081206 0930  Neupogen...... 480 mcg  960......... ref SDS D0 BI4J
041005 -             ..
041006 -       24.  081207 0700  1 10   901.0  10   500    4   20 ... ref SDS D1 OE6K
041007 -       25.  081208 0700  1 11   938.5  11   550    4   20 ... ref SDS D2 OE6K
041008 -       26.  081209 0700  1 12   976.0  12   600    4   20 ... ref SDS D3 OE6K
041009 -             ..
041010 -       27.  081210 0700  1 13  1013.5  13   650    4   20 ... ref SDS D5 OE6K
041011 -
041012 -            081210 1301. NEUTS....... 1.085 ................. ref SDS D6 QY6H
041014 -             ..
041015 -       28.  081211 0700  1 14  1050.0  14   700    4   20 ... ref SDS D9 OE6K
041016 -             ..
041017 -       29.  081212 0700  1 15  1087.5  15   750    5   25 ... ref SDS E1 OE6K
041018 -
041019 -            081212 1115. NEUTS....... 1.054 ................. ref SDS E2 QY6H
041021 -             ..
041022 -       30.  081213 0700  1 16  1125.0  16   800    6   30 ... ref SDS E4 OE6K
041023 -       31.  081214 0700  1 17  1162.5  17   850    6   30 ... ref SDS E5 OE6K
041024 -       32.  081215 0700  1 18  1200.0  18   900    6   30 ... ref SDS E6 OE6K
041025 -       33.  081216 0700  1 19  1237.5  19   950    6   30 ... ref SDS E7 OE6K
041026 -             ..
041027 -       34.  081217 0700  1 20  1275.0  20  1000    6   30 ... ref SDS E8 OE6K
041028 -       35.  081218 0700  1 21  1312.5  21  1050    canceled.. ref SDS F0 OE6K
041029 -
041030 -            081218 0830. NEUTS....... 0.740 ................. ref SDS F1 QY6H
041032 -             ..
041033 -            081219 0700  2  1  paused until 081226........... ref SDS F3 OE6K
041035 -             ..
041036 -            081219 1130  Neupogen...... 480 mcg 1440 ........ ref SDS F4 UZ7K
041037 -            081220 0900  Neupogen...... 480 mcg 1920 ........ ref SDS F6 UZ7K
041039 -             ..
041040 -       36.  081226 0700  2  1  1350.0  22  1100.............. ref SDS G2 OE6K
041041 -       37.  081227 0700  2  2  1387.5  23  1150.............. ref SDS G4 OE6K
041042 -       38.  081228 0700  2  3  1425.0  24  1200.............. ref SDS G5 OE6K
041043 -       39.  081229 0700  2  4  1462.5  25  1250.............. ref SDS G6 OE6K
041044 -       40.  081230 0700  2  5  1500.0  26  1300.............. ref SDS 0 OE6K
041046 -  ..
041047 - Background on recent blood tests is reported on 081218. ref SDS F0
041048 - S18L
041049 -
041050 -
041051 -
041052 -
041053 -
0411 -

SUBJECTS
Default Null Subject Account for Blank Record

0503 -
050401 -  ..
050402 - Side Effects Sunitinib Study with Cyclophosphamide Methotrexate
050403 -
050404 - Follow up ref SDS G6 LF8M, ref SDS G5 LF8M.
050405 -
050406 - Fatigue is a likely side effect of sunitinib with cyclophosphamide,
050407 - listed in the Consent document reviewed on 081017. ref SDS 76 4G7G
050409 -  ..
050410 - Blood counts NEUTS 1.710 reported on 081226, ref SDS G3 B35J increased
050411 - substantially more than doubling from NEUTS 0.740, reported at UCSF on
050412 - 081218, ref SDS F1 QY6H, which at that time were causing severe
050413 - fatigue, reported meeting at UCSF on 081218. ref SDS F2 WS4J  Cancer
050414 - treatment started on 081226, after pausing for a week, and getting 2
050415 - Neupogen treatments, reported on 081220. ref SDS F6 P73J  Substantial
050416 - increase in blood counts and energy accomplishes Doctor Rugo's work
050417 - plan on 081218. ref SDS F2 BQ8F
050419 -  ..
050420 - Millie had severe diarrhea today at Kaiser while getting a CT test.
050421 - ref SDS G8 FF4K  This is a side effect of sunitinib, reported on
050422 - 081017. ref SDS 76 C78M  During the first 10 weeks of sunitinib
050423 - treatment, Millie only experienced 2 previous episodes, shown in
050424 - patient history below. ref SDS 0 MV5H  Since Millie resumed treatment
050425 - with sunitinib on 081226, ref SDS G2 555J, this may have increased
050426 - cause of diarrhea from barrium sulfate suspension which is a contrast
050427 - taken orally for the CT test, ref SDS G8 FD9N, based on similar
050428 - problems using barrium sulfate for the CT test on 080911, cited also
050429 - on 081230. ref SDS G8 N66M
050431 -  ..
050432 - When Millie got home from Kaiser after the CT test, she took Imodium,
050433 - which has been effective treating diarrhea.  She had no further
050434 - problems the rest of the day.
050436 -  ..
050437 - Background on Neupogen treatments and UCSF comments are reported on
050438 - 081207. ref SDS D1 673J
050440 -  ..
050441 - NEUTS blood tests show patient history of treatments with Nuepogen to
050442 - recover from neutropenia caused by getting chemotherapy everyday with
050443 - cyclophosphamide reported in case study on 081205. ref SDS C5 EC5N
050445 -  ..
050446 - Schedule for Neupogen treatments is listed on 081220. ref SDS F6 WJ4O
050448 -  ..
050449 - Today, Millie still tired from the hike on 081227, ref SDS G6 6E7G;
050450 - she also had a CT test, ref SDS G8 3G5I, and so did not go hiking.
050451 - ref SDS G6 X64F
050453 -  ..
050454 - Feet and toes continue better today, less sensitive to walking that
050455 - was reported during the meeting at UCSF on 081218. ref SDS F2 HM4M
050456 - Subsiding side effects restoring normal use of feet enabled hiking,
050457 - but Millie is tired today, so we did not go hiking, per below.
050458 - ref SDS G5 X64F
050460 -  ..
050461 - Joint pain, discomfort, and total ill feeling, commonly associated
050462 - with chemotherapy, reported on 081218, ref SDS F0 E38H, and discussed
050463 - with the medical team at UCSF also on 081218, ref SDS F2 QW7H, has now
050464 - mostly disipated, as a result of the doctor stopping all treatment for
050465 - 1 week, ref SDS F2 QW48, as shown in patient history above.
050466 - ref SDS G5 053F
050468 -  ..
050469 - Interstitional lung disease discussed in the record on 081218,
050470 - ref SDS F0 KM5F, shows no evident symptoms.
050472 -  ..
050473 - Vitals were reported today at the meeting at Kaiser with the primary
050474 - care physician...
050475 -
050476 -                   BP *** ** pulse **
050478 -  ..
050479 - Millie reports continued relief from heartburn with daily treatments
050480 - using Prilosce started on 081208. ref SDS D2 7J6K
050482 -  ..
050483 - Sore throat problem, reported initially on 081218, as having begun
050484 - days earlier, ref SDS F0 2B8M, seems better today today continuing
050485 - relief reported yesterday on 081222. ref SDS F8 TT4O  This increases
050486 - interest in eating food.  Millie had eggs and a baggel for a late
050487 - lunch after returning from the gym.  Swallowing seems much more normal
050488 - now.
050490 -  ..
050491 - Millie reports improved taste from some foods today (e.g., soup),
050492 - cited in study consent documents, reviewed on 081017. ref SDS 76 6T5H
050494 -     ..
050495 -                                   Date
050496 -    Description Adverse Event   Start  Stop     Medication
050497 -    ---------------------------------------------------------
050498 -    Follow up ref SDS G6 MV5H, ref SDS G5 MV5H.
050499 -
050500 -    Diarrhea                    081114 081114   Imodium........ ref SDS 94 LF8M
050501 -    Low pulse                   081120 081120   None........... ref SDS A3 LF8M
050502 -    Low pulse                   081121 081121   None........... ref SDS A4 7G8M
050503 -    BP 144 84 Pulse 48          081121 081121   Hiking......... ref SDS A4 LF8M
050504 -    Joint pain minor            081121 081121   Hiking......... ref SDS A4 LF8M
050505 -    Fatigue minor               081121 081121   Hiking......... ref SDS A4 LF8M
050506 -    Low pulse                   081122 081122   None........... ref SDS A5 7G8M
050507 -    Fatigue minor               081122 081122   Hiking......... ref SDS A5 LF8M
050508 -    Low pulse                   081123 081122   None........... ref SDS A6 7G8M
050509 -    BP 121 74 Pulse 53          081123 081123   Hiking......... ref SDS A6 LF8M
050510 -    Fatigue minor               081123 081122   Hiking......... ref SDS A6 LF8M
050511 -    Joint pain minor            081124 081124   Hiking......... ref SDS A7 LF8M
050512 -    Fatigue minor               081124 081124   Hiking......... ref SDS A7 LF8M
050513 -    Heartburn                   081124 081124   None........... ref SDS A7 HS9K
050514 -    BP 144 78 Pulse 52          081125 081125   Hiking......... ref SDS A8 LF8M
050515 -    Joint pain minor            081125 081125   Hiking......... ref SDS A8 LF8M
050516 -    Fatigue minor               081125 081125   Hiking......... ref SDS A8 LF8M
050517 -    Heartburn                   081125 081125   None........... ref SDS A8 HS9K
050518 -    Heartburn                   081126 081126   None........... ref SDS A9 HS9K
050519 -    Heartburn                   081127 081127   None........... ref SDS B3 HS9K
050520 -    BP 135 73 Pulse 48          081128 081128   Hiking......... ref SDS B4 5X6K
050521 -    Upset stomach               081128 081128   Hiking......... ref SDS B4 T76O
050522 -    BP 140 75 Pulse 50          081129 081129   Hiking......... ref SDS B7 5X6K
050523 -    Heartburn                   081129 081129   None........... ref SDS B7 HS9K
050524 -     ..
050525 -    Fatigue                     081129 081129   Rest........... ref SDS B7 LF8M
050526 -    Fatigue                     081130 081130   Rest........... ref SDS B8 LF8M
050527 -    BP 136 79 Pulse 46          081201 081201   Hiking......... ref SDS B9 5X6K
050528 -    Fatigue                     081201 081201   Rest........... ref SDS B9 LF8M
050529 -    Taste altered               081201 081201   Rest........... ref SDS B9 VP4G
050530 -    BP 141 77 Pulse 46          081202 081202   Aerobics gym... ref SDS C1 5X6K
050531 -    Fatigue                     081202 081202   Rest........... ref SDS C1 LF8M
050532 -    Taste altered               081202 081202   Rest........... ref SDS C1 VP4G
050533 -    BP 138 77 Pulse 48          081203 081203   Hiking......... ref SDS C3 5X6K
050534 -    Fatigue                     081203 081203   Rest........... ref SDS C3 LF8M
050535 -    Taste altered               081203 081203   Rest........... ref SDS C3 VP4G
050536 -    NEUTS (ANC)     0.624       081203 081203   Neupogen.......
050537 -    BP 133 72 Pulse 45          081204 081204   Rest........... ref SDS C4 5X6K
050538 -    Fatigue                     081204 081204   Rest........... ref SDS C4 LF8M
050539 -    Taste altered               081204 081204   Rest........... ref SDS C4 VP4G
050540 -    BP 138 76 Pulse 49          081205 081205   Rest........... ref SDS C5 5X6K
050541 -    Diarrhea                    081205 081114   Imodium........ ref SDS C5 Q67F
050542 -    Fatigue                     081205 081205   Rest........... ref SDS C5 LF8M
050543 -    Taste altered               081205 081205   Rest........... ref SDS C5 VP4G
050544 -    BP *** ** Pulse **          081206 081206   Rest........... ref SDS C9 5X6K
050545 -    Fatigue                     081206 081206   Rest........... ref SDS C9 LF8M
050546 -    BP 128 70 Pulse 53          081207 081207   Hiking......... ref SDS D1 5X6K
050547 -    Fatigue                     081207 081207   Rest........... ref SDS D1 LF8M
050548 -    BP 137 68 Pulse 53          081208 081208   Rest........... ref SDS D2 5X6K
050549 -    Fatigue                     081208 081208   Rest........... ref SDS D2 LF8M
050550 -    BP *** ** Pulse **          081209 081209   Rest........... ref SDS D2 5X6K
050551 -    Fatigue                     081209 081209   Rest........... ref SDS D2 LF8M
050552 -    Heartburn                   081209 081209   Prilosec....... ref SDS D3 7J6K
050553 -    BP 136 70 Pulse 53          081210 081210   Rest........... ref SDS D5 5X6K
050554 -    Fatigue                     081210 081210   Rest........... ref SDS D5 LF8M
050555 -    Heartburn                   081210 081210   Prilosec....... ref SDS D5 7J6K
050556 -    BP *** ** Pulse **          081211 081211   Rest........... ref SDS D9 5X6K
050557 -    Fatigue                     081211 081211   Exercise gym... ref SDS D9 LF8M
050558 -    Heartburn                   081211 081211   Prilosec....... ref SDS D9 7J6K
050559 -    BP 137 76 Pulse 53          081212 081212   Rest........... ref SDS E1 5X6K
050560 -    Fatigue                     081212 081212   Exercise gym... ref SDS E1 LF8M
050561 -    Heartburn                   081212 081212   Prilosec....... ref SDS E1 7J6K
050562 -    BP 147 80 Pulse 51          081213 081213   Rest........... ref SDS E4 5X6K
050563 -    Fatigue                     081213 081213   Exercise gym... ref SDS E4 LF8M
050564 -    BP *** ** Pulse **          081214 081214   Rest........... ref SDS E5 5X6K
050565 -    Fatigue                     081214 081214   Rest........... ref SDS E5 LF8M
050566 -    BP *** ** Pulse **          081215 081215   Rest........... ref SDS E6 5X6K
050567 -    Fatigue                     081215 081215   Rest........... ref SDS E6 LF8M
050568 -    BP 144 79 Pulse 54          081216 081216   Rest........... ref SDS E7 5X6K
050569 -    Fatigue                     081216 081216   Exercise gym... ref SDS E7 LF8M
050570 -     ..
050571 -    Joint pain minor            081216 081216   Rest........... ref SDS E7 E38H
050572 -    BP 137 69 Pulse 63          081217 081217   Rest........... ref SDS E8 5X6K
050573 -    Fatigue                     081217 081217   Rest........... ref SDS E8 LF8M
050574 -    Joint pain minor            081217 081217   Rest........... ref SDS E8 E38H
050575 -    Nosebleed minor             081217 081217   Rest........... ref SDS E8 ZF5F
050576 -     ..
050577 -    BP *** ** Pulse **          081218 081218   Rest........... ref SDS F0 5X6K
050578 -    Fatigue                     081218 081218   Rest........... ref SDS F0 LF8M
050579 -    Joint pain minor            081218 081218   Rest........... ref SDS F0 E38H
050580 -    Nosebleed moderate          081218 081218   Rest........... ref SDS F0 ZF5F
050581 -    Throat pain eating          081218 081218   Eating less.... ref SDS F0 2B8M
050582 -    BP 155 84 Pulse 53          081219 081219   Rest........... ref SDS F3 5X6K
050583 -    Fatigue                     081121 081219   Rest........... ref SDS F3 LF8M
050584 -    Feet toes lesions           081219 081219   Rest........... ref SDS F3 UO8I
050585 -    Joint pain ill feeling      081121 081219   Rest........... ref SDS F3 E38H
050586 -    Throat sore eating          081218 081219   Eating less.... ref SDS F3 TT4O
050587 -    BP 123 69 pulse 53          081220 081220   Rest........... ref SDS F5 5X6K
050588 -    Fatigue                     081121 081220   Rest........... ref SDS F5 LF8M
050589 -    Feet toes lesions           081219 081220   Rest........... ref SDS F5 UO8I
050590 -    Joint pain ill feeling      081121 081220   Rest........... ref SDS F5 E38H
050591 -    Throat sore eating          081218 081220   Eating less.... ref SDS F5 TT4O
050592 -    BP 117 71 pulse 65          081221 081221   Rest........... ref SDS F7 5X6K
050593 -    Fatigue                     081121 081221   Rest........... ref SDS F7 LF8M
050594 -    Feet toes lesions           081219 081221   Rest........... ref SDS F7 UO8I
050595 -    Joint pain ill feeling      081121 081221   Rest........... ref SDS F7 E38H
050596 -    Throat sore eating          081218 081221   Eating less.... ref SDS F7 TT4O
050597 -    BP 117 71 pulse 65          081222 081222   Rest........... ref SDS F8 5X6K
050598 -    Fatigue                     081121 081222   Rest........... ref SDS F8 LF8M
050599 -    Feet toes lesions           081219 081222   Rest........... ref SDS F8 UO8I
050600 -    Joint pain ill feeling      081121 081222   Rest........... ref SDS F8 E38H
050601 -    Throat sore eating          081218 081222   Eating less.... ref SDS F8 TT4O
050602 -    BP 143 68 pulse 65          081223 081223   Rest........... ref SDS F8 5X6K
050603 -    Fatigue more energy         081121 081223   Exercise gym... ref SDS F9 LF8M
050604 -    Feet feel better            081219 081223   Exercise gym... ref SDS F9 UO8I
050605 -    Joint pain subsides         081121 081223   Exercise gym... ref SDS F9 E38H
050606 -    Throat sore improved        081218 081223   Eating normal.. ref SDS F9 TT4O
050607 -    BP *** ** pulse **          081224 081224   Rest........... ref SDS G0 5X6K
050608 -    Fatigue more energy         081121 081224   Exercise gym... ref SDS G0 LF8M
050609 -    Feet feel better            081219 081224   Exercise gym... ref SDS G0 UO8I
050610 -    Joint pain subsides         081121 081224   Exercise gym... ref SDS G0 E38H
050611 -    Throat sore improved        081218 081224   Eating normal.. ref SDS G0 TT4O
050612 -    BP 124 80 pulse 66          081225 081225   Rest........... ref SDS G1 5X6K
050613 -    Fatigue more energy         081121 081225   Activity....... ref SDS G1 LF8M
050614 -    Fatigue more energy         081121 081226   Activity....... ref SDS G2 LF8M
050615 -    BP *** ** pulse **          081227 081227   Rest........... ref SDS G4 5X6K
050616 -    Fatigue more energy         081121 081227   Hiking......... ref SDS G4 LF8M
050617 -    BP *** ** pulse **          081228 081228   Rest........... ref SDS G5 5X6K
050618 -    Fatigue more energy         081121 081228   Rest........... ref SDS G5 LF8M
050619 -    BP *** ** pulse **          081229 081229   Rest........... ref SDS G6 5X6K
050620 -    Fatigue more energy         081121 081229   Rest........... ref SDS G6 LF8M
050621 -    BP *** ** pulse **          081230 081230   Rest........... ref SDS 0 5X6K
050622 -    Diarrhea                    081230 081230   Imodium........ ref SDS 0 KZ9N
050623 -    Fatigue more energy         081121 081230   Rest........... ref SDS 0 LF8M
050624 -
050625 -
0507 -

SUBJECTS
Default Null Subject Account for Blank Record

0603 -
060401 -  ..
060402 - Exercise Hiking Maintain Fitness Strengthen Immune System
060403 -
060404 - Follow up ref SDS G6 3E4K, ref SDS G5 3E4K.
060405 -
060406 - Today, Millie still tired from the hike on 081227, ref SDS G6 6E7G;
060407 - she also had a CT test, ref SDS G8 3G5I, and so did not go hiking.
060408 - ref SDS G6 X64F
060410 -  ..
060411 - NEUTS blood tests show patient history treatments with Nuepogen for
060412 - neutropenia from chemotherapy everyday with cyclophosphamide reported
060413 - in case study on 081205. ref SDS C5 EC5N
060415 -  ..
060416 - On 081110, Millie complained about difficulty lifting herself from a
060417 - full squatting position. ref SDS 90 HX67  For several weeks, she was
060418 - exercising to strengthen legs, and arms, shown by going to the gym on
060419 - 081211. ref SDS D9 3E4K  Rising fatigue now prevents continuing
060420 - exercise.
060421 -
060423 -  ..
060424 - Case Study on Pateint History Exercising
060425 -
060426 - Follow up ref SDS G6 X64F, ref SDS G5 X64F.
060427 -
060428 -                                              +- scm = Sunitinib Cyclophosphmaide Methotrexate
060429 -                                              +- sc  = Sunitinib Cyclophosphmaide
060430 -                           Time     Pulse     |
060431 -    Location        Miles Minutes  Avg Max  Chem  Neupo  Date
060432 -    ----------------------------------------------------------------
060433 -    Concord home                              sc        081230, ref SDS 0 3E4K
060434 -    Concord home                              sc        081229, ref SDS G6 3E4K
060435 -    Concord home                              sc        081228, ref SDS G5 3E4K
060436 -    Lafayette        2.75   56.2    90 112    sc        081227, ref SDS G4 3E4K
060437 -    Concord home                              sc        081226, ref SDS G2 3E4K
060438 -    Concord travel                                      081225, ref SDS G1 3E4K
060439 -    Concord home                                        081224, ref SDS G0 3E4K
060440 -    Concord home (gym)                                  081223, ref SDS F9 3E4K
060441 -    Concord home                                        081222, ref SDS F8 3E4K
060442 -    Concord home                                        081221, ref SDS F7 3E4K
060443 -    Concord home                                        081220, ref SDS F5 3E4K
060444 -    Concord home                                        081219, ref SDS F3 3E4K
060445 -    Concord home                              sc        081218, ref SDS F0 3E4K
060446 -    Concord home                              sc        081217, ref SDS E8 3E4K
060447 -    Concord home (gym)                        sc        081216, ref SDS E7 3E4K
060448 -    Concord home                              sc        081215, ref SDS E6 3E4K
060449 -    Concord home                              sc        081214, ref SDS E5 3E4K
060450 -    Concord home (gym)                        scm       081213, ref SDS E4 3E4K
060451 -    Concord home                              scm       081212, ref SDS E1 3E4K
060452 -    Concord home (gym)                        sc        081211, ref SDS D9 3E4K
060453 -    Concord home                              sc        081210, ref SDS D5 3E4K
060454 -    Concord home                              sc        081209, ref SDS D3 3E4K
060455 -    Concord home                              sc        081208, ref SDS D2 3E4K
060456 -    Lafayette        4.75   78.6    95 110    sc        081207, ref SDS D1 3E4K
060457 -    Concord home                              scm       081206, ref SDS C9 3E4K
060458 -    Concord home                              scm       081205, ref SDS C5 3E4K
060459 -    Concord home                              sc        081204, ref SDS C4 3E4K
060460 -    Lafayette        2.75   62.7    90 117    sc        081203, ref SDS C3 3E4K
060461 -    Concord home (gym)                        sc        081202, ref SDS C1 3E4K
060462 -    Lafayette        5.50  102.3    95 122    sc        081201, ref SDS B9 3E4K
060463 -    Concord home                              sc        081130, ref SDS B8 3E4K
060464 -    Lafayette        2.75   56.7    90 115    scm       081129, ref SDS B7 3E4K
060465 -    Lafayette        2.75   46.5   100 128    scm       081128, ref SDS B4 3E4K
060466 -    Lafayette        5.50   93.3   100 122    s         081127, ref SDS B3 3E4K
060467 -    Concord home                              s         081126, ref SDS A9 3E4K
060468 -    Lafayette        4.00   73.7   105 127    s         081125, ref SDS A8 3E4K
060469 -    Lafayette        5.50   91.4   100 129    s         081124, ref SDS A7 3E4K
060470 -    Concord home                              s         081123, ref SDS A6 3E4K
060471 -    Lafayette        5.50   92.8    95 122    s         081122, ref SDS A5 3E4K
060472 -    Lafayette        5.50   94.4    85 112    s         081121, ref SDS A4 3E4K
060473 -    Lafayette        5.50   94.7    90 122    s         081120, ref SDS A3 3E4K
060474 -    San Francisco    1.00   60.0    65  75    s         081119, ref SDS A2 3E4K
060475 -    Lafayette        2.75   49.2    97 130    s         081118, ref SDS A1 3E4K
060476 -    Lafayette        5.50   93.6   115 138    s         081117, ref SDS 98 3E4K
060477 -    Concord home                              s         081116, ref SDS 96 Y68J
060478 -    Concord home                              s         081115, ref SDS 95 EK7I
060479 -    Concord home                              s         081114, ref SDS 94 XW6H
060480 -    Lafayette        5.50   94.2   115 138              081110, ref SDS 90 3E4K
060481 -    Lafayette        2.75   48.4   105 128              081109, ref SDS 89 3E4K
060482 -    Kaiser                                         x    081108, ref SDS 88 UZ7K
060483 -    Kaiser                                         x    081107, ref SDS 87 UZ7K
060484 -    Lafayette        5.50   90.2   120 143              081025, ref SDS 83 3E4K
060485 -    Kaiser                                         x    081025, ref SDS 83 UZ7K
060486 -    Kaiser                                         x    081024, ref SDS 82 UZ7K
060487 -    UCSF                                      c         081023, ref SDS 81 V94O
060488 -    Lafayette        5.50   90.6   115 141              081021, ref SDS 80 3E4K
060489 -    Lafayette        5.50   90.4   110 128              081020, ref SDS 79 3E4K
060490 -    Kaiser                                         x    081018, ref SDS 78 UZ7K
060491 -    Kaiser                                         x    081017, ref SDS 77 UZ7K
060492 -    UCSF                                      e         081016, ref SDS 75 V94O
060493 -    Lafayette        5.50   90.1   115 154              081014, ref SDS 74 3E4K
060494 -    Lafayette        5.50   92.7   115 138              081013, ref SDS 73 3E4K
060495 -    Lafayette        8.25  146.4   180 224              081012, ref SDS 72 3E4K
060496 -    Kaiser                                         x    081011, ref SDS 71 UZ7K
060497 -    Lafayette        5.50   93.3   116 138              081010, ref SDS 70 3E4K
060498 -    Kaiser                                         x    081010, ref SDS 70 UZ7K
060499 -    UCSF                                      e         081009, ref SDS 69 V94O
060500 -    Lafayette        5.50   92.1   113 137              081006, ref SDS 68 3E4K
060501 -    Lafayette        2.75   48.5   110 136         x    081004, ref SDS 67 3E4K
060502 -    Lafayette        5.50   98.2   117 136         x    081003, ref SDS 66 3E4K
060503 -    UCSF                                      c         081002, ref SDS 65 V94O
060504 -    Lafayette        5.50   94.7   115 142              080929, ref SDS 64 3E4K
060505 -    Lafayette        8.25  150.4   115 135              080928, ref SDS 64 3E4K
060506 -    Kaiser                                         x    080927, ref SDS 63 UZ7K
060507 -    Lafayette        5.50   90.2   120 140         x    080926, ref SDS 62 3E4K
060508 -    UCSF                                      c         080925, ref SDS 61 V94O
060509 -    Lafayette        5.50   92.3   116 138              080923, ref SDS 60 3E4K
060510 -    Lafayette        5.50   98.4   112 134              080922, ref SDS 60 3E4K
060511 -    Lafayette        5.50   98.2   114 137              080921, ref SDS 60 3E4K
060512 -    Lafayette        5.50  101.6   110 133         x    080920, ref SDS 59 3E4K
060513 -    Lafayette        5.50   89.3   115 144         x    080919, ref SDS 58 3E4K
060514 -    UCSF                                      c         080918, ref SDS 57 V94O
060515 -    Lafayette        2.75   46.2   117 139              080916, ref SDS 58 3E4K
060516 -    Lafayette        5.50   91.8   117 142              080915, ref SDS 56 3E4K
060517 -    Clayton Safeway  3.00   62.4    98 118              080914, ref SDS 55 3E4K
060518 -    Lafayette        8.25  129.7   123 147         x    080913, ref SDS 54 3E4K
060519 -    Lafayette        5.50   88.4   118 146         x    080912, ref SDS 53 3E4K
060520 -    UCSF                                      c         080911, ref SDS 52 V94O
060521 -    Lafayette        2.75   46.8   113 140              080909
060522 -    Lafayette        5.50   89.2   117 143              080908
060523 -    Lafayette        5.50   92.1   115 138              080907
060524 -    Lafayette        2.75   45.3   120 144         x    080906, ref SDS 51 3E4K
060525 -    Lafayette        2.75   56.8    93 120         x    080905, ref SDS 50 3E4K
060526 -    UCSF                                      c         080904, ref SDS 49 V94O
060527 -    Lafayette        8.25  140.4   116 131              080903
060528 -    Lafayette        5.50   94.9   115 134              080902
060529 -    Kaiser                                         x    080830
060530 -    Kaiser                                         x    080829
060531 -    UCSF                                      c         080828, ref SDS 48 V94O
060532 -    Lafayette        5.50   93.6   120 137              080826
060533 -    Lafayette        5.50   93.2   117 138              080825
060534 -    Lafayette        5.50   93.2   123 136         x    080823
060535 -    Lafayette        8.25  142.5   110 131         x    080822, ref SDS 47 3E4K
060536 -    UCSF                                      e         080821, ref SDS 46 V94O
060537 -    Lafayette        5.50   94.7   115 137              080820
060538 -    Lafayette        5.50   94.3   115 135              080819
060539 -    Lafayette        8.25  141.7   118 134              080815
060540 -    UCSF                                      e         080814, ref SDS 45 V94O
060541 -    Lafayette        5.50   93.8   120 136              080813
060542 -    Lafayette        5.50   94.4   116 139              080812
060543 -    Lafayette        5.50   94.2   119 133              080810
060544 -    Lafayette        8.25  143.6   114 132         x    080809, ref SDS 43 3E4K
060545 -    Lafayette        8.25  141.1   117 135         x    080808, ref SDS 42 3E4K
060546 -    UCSF                                      c         080807, ref SDS 41 V94O
060547 -    Lafayette        8.25  143.7   115 132              080805
060548 -    Concord          7.00  127.6   105 118              080804
060549 -    Lafayette        8.25  143.2   112 134              080802
060550 -    Lafayette        5.50   93.4   115 138              080801
060551 -    Lafayette        5.50   92.2   118 140              080729
060552 -    Lafayette        5.50   92.6   116 137              080728
060553 -    Lafayette        8.25  142.6   114 134              080727
060554 -    Lafayette        5.50   91.5   120 143              080726
060555 -    Lafayette        8.25  140.8   117 135              080725
060556 -    Lafayette        5.50   91.8   122 141              080723
060557 -    Lafayette        5.50   91.3   120 139              080722
060558 -    Lafayette        8.25  143.3   115 133              080720
060559 -    Lafayette        5.50   90.7   125 144              080719
060560 -    Lafayette        5.50   92.4   123 142              080716
060561 -    Lafayette        2.25   46.8   116 137              080715
060562 -    Lafayette        8.25  141.8   116 136              080712
060563 -    Lafayette        5.50   92.9   116 139              080711
060564 -    Lafayette        8.25  143.3   113 137              080704
060565 -    Lafayette        5.50   90.2   121 147              080630
060566 -    Lafayette        8.25  142.4   116 138              080628
060567 -    Lafayette        5.50   91.4   118 138              080625
060568 -    Lafayette        2.25   47.9   116 136              080623
060569 -    Lafayette        5.50   94.2   112 138              080622
060570 -    Lafayette        5.50   94.7   115 133              080621
060571 -    Lafayette        2.25   48.3   110 129              080620
060572 -    Mt Diablo        7.00  129.4   130 153              080616
060573 -    Lafayette        5.50   90.8   120 146              080615
060574 -    Lafayette        5.50   91.3   124 144              080614
060575 -    Lafayette        5.50   89.7   122 143              080613
060576 -    Lafayette        2.76   45.8   120 147              080611
060577 -    Lafayette        5.50   90.5   123 145              080609
060578 -    Lafayette        5.50   92.7   115 138              080607
060579 -    Lafayette        5.50   94.2   118 139              080602
060580 -    Lafayette        5.50   96.2   110 202              080507, ref SDS 19 WO8M
060581 -
060582 -
060583 -
060584 -
060585 -
060586 -
0606 -