THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rod@welchco.com
S U M M A R Y
DIARY: February 3, 2014 11:47 AM Monday;
Rod Welch
VA lab with lipid panel test cholesterol for LDL-P discordance.
1...Summary/Objective
2...Blood Tests Evaluate Health 4 Years After CABG x4 Surgery
........CBC........... 2014 02 03 0952 140201 130529
3...Urinalysis Gross Exam Laboratory Test Satisfactory Within Range
........URINALYSIS.....2014 02 03 0952 140201 120509
4...Total Bilirubin 1.6 Due to Rosuvastatin Recovery Failing
5...Hyperbilirubinemia Persists after Ending Rosuvastatin
6...Potasium K 5.4 Elevated above May Affect Heart Function
...........................ELECTROLYTES - CHEM PROFILE
7...Notes on Electrolytes Lab
8...LDL-C 81 LDL-P 861 LDL Size Large Hike 1000 Miles Weight Lose 15 Pounds
9...Follow up testing can take several directions...
10...Rosuvastatin Switch from Simvastatin Myopathy Side Effects Decline
11...Simvistatin Side Effects Myopathy Muscle Pain Decline Switch to Rosuvastatin
12...Myopathy Muscle Pain Side Effects Simvistatin Decline Switch to Rosuvastatin
.............................CARDIAC ENZYMES
13...HGBA1c Diabetes Blood Test
14...Diabetes Blood Test HGBA1c
.............................HGBA1c
..............
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CONTACTS
SUBJECTS
CBC Lab WBC VA
1503 -
1503 - ..
1504 - Summary/Objective
1505 -
150501 - Follow up ref SDS 47 0000. ref SDS 32 0000.
150502 -
150503 - Lab today in Martinez shows excellent progress by the VA prescribing
150504 - continued weight loss, exercise, diet control with minimal statin
150505 - medications. Lipid profile TG/HDL ratio indicates LDL-P 626,
150506 - ref SDS 0 4Z66, has fallen further below 1000, and dominate sizes are
150507 - large, buoyant LDL particles protect against arterialsclorosis and
150508 - cardiovascular disease (CVD). ref SDS 0 5C7M Statin drugs lowered
150509 - LDL-C making patient concordant, higher risk for CVD events, than
150510 - occurs for discordant status. ref SDS 47 3V4N Electrolytes lab shows
150511 - potassium increased (K 5.4) above healthy range. ref SDS 0 TN3M T
150512 - Bilirubin continues elevated, indicating possible liver damage.
150513 - ref SDS 0 G34G
150514 -
150515 - [On 140211 0133 letter to medical team at SFVA Med Center
150516 - for agenda to prepare for meeting on 140213, notifies that
150517 - total bilirubin and potassium are elevated in VA lab, and
150518 - Labcorp reports these blood elements are stable.
150519 - ref SDS 50 TV5F
150520 -
150521 -
150522 -
150524 - ..
1506 -
1507 -
1508 - Background
1509 -
150901 - On 131016 1632 submit letter for agenda meeting to review lab results
150902 - scheduled 131017 1000. ref SDS 33 X45G
150904 - ..
150905 - On 140131 0815 ordered another lab - cbc, electrolytes, lipid with NMR
150906 - - from Labcor to get LDL-P. ref SDS 46 X45G
150907 -
150908 -
150909 -
150911 - ..
1510 -
1511 -
1512 - Progress
1513 -
151301 - Blood draw today at VA health care facility for meeting at VA with
151302 - Doctor Alba on 140213, planned in the meeting on 131219 0930.
151303 - ref SDS 43 XF4O The letter to VA asked for instructions to get blood
151304 - draw at VA in San Francisco or in Martinez. Since, the VA has not
151305 - responded, and since the Martinez clinic is closer, had blood drawn
151306 - there today.
151307 -
151308 - [On 140204 1236 letter from VA says to get blood draw for
151309 - lab at VA San Francisco Medical Center (SFMC), ref SDS 49
151310 - PT3M, responding to inquiry in letter to VA on 140128.
151311 - ref SDS 45 TZ96
151313 - ..
151314 - Blood draw today compliments test 2 days ago with Labcorp to perform
151315 - NMR lipid analysis. 140201 1159, ref SDS 47 IM9N
151317 - ..
151318 - Blood draw today follows up previous partial lab on 131015 0724.
151319 - ref SDS 32 KK9M
151321 - ..
151322 - Planned for blood draw Monday or Tuesday next week, but injury
151323 - yesterday, perhaps from excessive hiking the past few months, reported
151324 - in case study on 120101 0900, ref SDS 14 WQ4I, prevents hiking today,
151325 - and possibly tomorrow as well. Since had a good hike yesterday, and
151326 - weight is near 165, decided to get blood draw today, so there is
151327 - correlation between labs, exercise, and weight.
151329 - ..
151330 - Last full lab was on 130529 0818. ref SDS 30 RP4N
151332 - ..
151333 - Prior full lab was on 121130 0846, ref SDS 24 RP4N, 120831 1400.
151334 - ref SDS 20 RP4N, following up 120509 1108, ref SDS 19 X45G; and before
151335 - that on 110727 1238, ref SDS 9 RP4N, and this was to prepare for
151336 - meeting in Primary Care a few weeks later on 110803 1400. ref SDS 10
151337 - U24I
151339 - ..
151340 - Partial lab to resolve skewed results from dehydration was on 121212
151341 - 0941. ref SDS 26 KK9M
151343 - ..
151344 - Prior partial for lipid panel testing cholesterol and for glucose,
151345 - sodium, and total bilirubin was on 131015 0724, ref SDS 32 KK9M,
151346 - following up partial lab on 120831 1400. ref SDS 20 IM9N and
151347 - ref SDS 20 KK9M
151348 -
151350 - ..
151351 - Blood Tests Evaluate Health 4 Years After CABG x4 Surgery
151352 -
151353 - Follow up ref SDS 47 RP4N, ref SDS 32 RP4N.
151354 -
151355 - Prior VA CBC on 120509 1108. ref SDS 19 RP4N
151356 - Prior VA CBC on 120831 1524. ref SDS 20 RP4N
151357 - Prior VA CBC on 121130 1001. ref SDS 24 RP4N
151358 - Prior VA CBC on 130529 0818. ref SDS 30 RP4N
151359 - Prior Labcorp CBC on 140201 1159. ref SDS 47 RP4N
151361 - ..
151362 - VA did not order CBC for lab today...
151364 - ..
151365 - CBC........... 2014 02 03 0952 140201 130529
151366 - VA Labcorp VA VA Labcorp
151367 - Blood Results Results Results Units Range Range
151368 - WBC 6.2 7.4 K/cmm 4.8 - 10.8 3.4 - 10.8
151369 - RBC 5.13 5.09 M/cmm 4.7 - 6.1 4.14 - 5.80
151370 - HGB 15.2 15.0 g/dL 14 - 18 12.6 - 17.7
151371 - HCT 44.2 46.2 % 42 - 52 37.5 - 51.0
151372 - MCV 86.0 90.7 fL 80 - 99 79.0 - 97.0
151373 - MCH 29.6 29.5 uug 27 - 34 26.6 - 33.0
151374 - MCHC 34.4 32.5 gm/dL 32 - 35.2 31.5 - 35.7
151375 - RDW 13.7 14.4 % 11.5 - 14.5 12.3 - 15.4
151376 - PLT 303 279 K/cmm 130 - 400 155.0 - 379.0
151377 - MPV 8.8 fL 7 - 10.4
151378 - NEUT % 69 69.9 % 40 - 80 40.0 - 74.0
151379 - LYMPH % 21 L 19.7 % 20 - 51 14.0 - 46.0
151380 - MONO % 8 7.8 % 2 - 13 4.0 - 12.0
151381 - EOS % 1 1.9 % .5 - 7 0.0 - 5.0
151382 - BASO % 1 0.7 % 0 - 2 0.0 - 3.0
151383 - NEUT # 4.3 5.2 K/cmm 1.5 - 7.9 1.4 - 7.0
151384 - LYMPH # 1.3 1.5 K/cmm 1.2 - 3.4 0.7 - 3.1
151385 - MONO # 0.5 0.6 K/cmm .2 - 1.2 0.1 - 0.9
151386 - EOS # 0.1 0.1 K/cmm .1 - .5 0.0 - 0.4
151387 - BASO # 0.1 0.1 K/cmm 0 - .2 0.0 - 0.2
151388 - ESRmVES mm/hr 0 - 10
151389 - ESRxCYT mm/hr 2 - 10
151390 - RETIC % % .66 - 2.85
151391 - RETIC # k/uL 27.9 - 121.6
151392 - Immature Granulocytes 0.0 % 0.0 - 2.0
151393 - Immature Grans (Abs) 0.0 % 0.0 - 0.1
151395 - ..
151396 - Comments:
151397 -
151398 - a. Test not performed at VA today.
151399 -
151400 -
151401 -
151402 -
1515 -
SUBJECTS
Urinalysis Gross Exam Laboratory Test Satisfactory Within Range Labc
2203 -
220401 - ..
220402 - Urinalysis Gross Exam Laboratory Test Satisfactory Within Range
220403 -
220404 - Follow up ref SDS 47 0X72, ref SDS 19 0X72.
220405 -
220406 - Prior Urinalysis test on 101207 0906. ref SDS 8 0X72
220407 - Prior Urinalysis test on 120509 1108. ref SDS 19 0X72
220408 - Prior Urinalysis test on 140201 1159. ref SDS 47 0X72
220410 - ..
220411 - VA did not order urinalysis for lab today...
220413 - ..
220414 - URINALYSIS.....2014 02 03 0952 140201 120509
220415 - VA Labcorp VA VA Labcorp
220416 - Results Results Results Units Range Range
220417 - PH 5.5 6.0 5 - 9 5.0 - 7.5
220418 - PROTEIN NEG NEG mg/dL NEG - TRACE NEG - TRACE
220419 - GLUCOSE NEG NEG mg/dL Ref: NEG NEG
220420 - KETONES NEG NEG mg/dL Ref: NEG NEG
220421 - BILI NEG NEG Ref: NEG NEG
220422 - BILIcnf Ref: NEG
220423 - BLOOD TRACE TRACE Ref: NEG
220424 - NITRITE, URINE NEG NEG Ref: NEG NEG
220425 - UROBILI 0.2 0.2 EU/dL .2 - 1 0.0 - 1.9
220426 - LEU EST NEG Ref: NEG
220427 - SP.GRAV 1.026 1.025 1.003- 1.035 1.005 - 1.030
220428 - COLOR YELLOW YELLOW
220429 - APPEAR CLEAR CLEAR
220430 - WBC ESTERASE NEG
220431 - OCCULT BLOOD NEG NEG
220433 - ..
220434 - Comments:
220435 -
220436 - a. Test not performed at VA today.
220437 -
220438 -
220439 -
220440 -
2205 -
SUBJECTS
VA Lab Electrolytes Chem Profile Glucose 103 Sodium NA 140 Potasium
3503 -
350401 - ..
350402 - Total Bilirubin 1.6 Due to Rosuvastatin Recovery Failing
350403 - Hyperbilirubinemia Persists after Ending Rosuvastatin
350404 - Potasium K 5.4 Elevated above May Affect Heart Function
350405 -
350406 - Follow up ref SDS 47 KK9M, ref SDS 32 KK9M.
350407 -
350408 - Prior CHEM PROFILE on 120509 1108. ref SDS 19 KK9M
350409 - Prior CHEM PROFILE on 120831 1524. ref SDS 20 KK9M
350410 - Prior CHEM PROFILE on 130228 1140. ref SDS 28 KK9M
350411 - Prior CHEM PROFILE on 130529 0818. ref SDS 30 KK9M
350412 - Prior CHEM PROFILE on 131015 0724. ref SDS 32 KK9M
350413 - Prior CHEM PROFILE Labcorp on 140201 1159. ref SDS 47 KK9M
350415 - ..
350416 - ELECTROLYTES - CHEM PROFILE
350418 - ..
350419 - CHEM PROFILE...2014 02 03 0952 140201 131015 130529
350420 - VA Labcorp VA VA VA Labcorp
350421 - PLASMA Results Results Results Results Units Range Range
350422 - GLUCOSE 103 98 108 H 120 mg/dL 74 - 118 65.0 - 99.0
350423 - GLUfast mg/dL Ref: <=99
350424 - NA (salt) 140 140 139 139 mmol/L 136 - 144 134.0 - 144.0
350425 - K (potasium) H 5.4 4.8 4.3 H 4.9 mmol/L 3.4 - 4.8 3.5 - 5.2
350426 - CL 103 102 105 105 mmol/L 98 - 106 97.0 - 108.0
350427 - CO2 30.0 37.0 30.0 mmol/L 23 - 33
350428 - BUN 17 20 24 18 mg/dL 8 - 26 10.0 - 22.0
350429 - CREAT 0.82 0.81 0.83 0.83 mg/dL .5 - 1.1 0.76 - 1.27
350430 - eGFR INA >60 91 >60 >60 mL/min Ref: >=60 >59
350431 - eGFR IA 106 mL/min >59
350432 - CALCIUM 9.3 9.4 9.2 9.2 mg/dL 8.7 - 10.2 8.6 - 10.2
350433 - CA CORR mg/dL 8.7 - 10.2
350434 - PO4 mg/dL 2.4 - 4.5
350435 - MG 85 mg/dL 1.8 - 2.5
350436 - ALK PHO 105 84 87 IntUnits/L 37 - 107 39.0 - 117.0
350437 - ..
350438 - T. BIL H 2.1 H 1.6 H 1.7 H 1.3 mg/dL .3 - 1.2 0.0 - 1.2
350439 - D. BILI 0.3 0.34 < 0.1 mg/dL .1 - .4 0.00 - 0.40
350440 - Bilirubin, Indir 1.26 H mg/dL 0.10 - 0.80
350441 - AST 23 21 20 22 IntUnits/L 8 - 42 0.0 - 40.0
350442 - ALT 21 19 17 19 IntUnits/L 5 - 55 0.0 - 44.0
350443 - ALBUMIN 4.1 4.4 3.9 4.0 g/dL 3.3 - 4.8 3.6 - 4.8
350444 - PROTEIN 6.7 6.5 7.1 7.2 g/dL 6.5 - 8.1 6.0 - 8.5
350445 - Globulin, Total 2.1 g/dL 1.4 - 4.5
350446 - A/G Ratio 2.1 1.1 - 2.5
350447 - LDH 180.0 IntUnits/L 90 - 208 0.0 - 225.0
350448 - GGT 9.0 IU/L 0.0 - 65.0
350449 - Iron, Serum 114.0 ug/dL 40.0 - 155.0
350450 - AMYLASE Units/L 28 - 100
350451 - LIPASE Units/L 7 - 58
350452 - NH3 mcmol/L 15 - 56
350453 - URIC AC mg/dL 4.8 - 8.7
350454 - Cholesterol, Total 162.0 mg/dL 100.0 - 199.0
350455 - Triglycerides 64.0 mg/dL 0.0 - 149.0
350457 - ..
350458 - Comments:
350459 -
350460 - a. TEST PERFORMED BY VA MARTINEZ, 150 MUIR ROAD, MARTINEZ CA.
350462 - ..
350463 - b. Evaluation for CREAT:
350464 -
350465 - Effective 7/2/08, new standardized method for
350466 - creatinine in place. Note reference range change.
350467 - Previous range 0.5-1.2 mg/dL.
350469 - ..
350470 - c. Evaluation for ALK PHO:
350471 -
350472 - The normal range is for an adult population less than
350473 - 50 years old. Alk Phos increases with age over 50 to
350474 - about 60% higher values by ages greater than 75 years
350475 - old.
350477 - ..
350478 - d. Evaluation for eGFR:
350479 -
350480 - eGFR Units = mL/min/1.73 square meters
350482 - ..
350483 - e. Ordering Provider: Vamc San Francisco
350484 - Report Released: Feb 03, 2014 @ 1232
350485 - Reporting Lab: Martinez OPC/CREC
350486 - 150 Muir Road Martinez, CA 94553 4668
350487 - Performing Lab: Martinez OPC/CREC
350488 - 150 Muir Road Martinez, CA 94553 4668
350490 - ..
350491 - Notes on Electrolytes Lab
350492 -
350493 -
350494 - 1. T Bilirubin 2.1................. ref SDS 0 015M
350495 -
350496 - Bilirubin 2.1 in lab today, remains 50% high after ending
350497 - Rosuvastatin 14 months ago on 121206 0900, ref SDS 25 OS5L,
350498 - indicating chornic side effects. Peripheral neuropathy has
350499 - declined from most severe effects; there have been no symptoms
350500 - for past 9 months, since 130614, reported in case study on
350501 - 120101 0900. ref SDS 14 TSUY Prior to 130614, there were no
350502 - episodes for several months reported on 130402, ref SDS 14
350503 - RURT, until episode occurred on 130210. ref SDS 14 PV8I Major
350504 - peripheral neuopathy both feet on 130107. ref SDS 14 8H5F
350506 - ..
350507 - Background on Rosuvastatin causing elevated T Bilirubin with
350508 - associated severe side effects is reported on 121206 0900, ref SDS 25
350509 - NI9L, and further explained in the record on 121130 0846. ref SDS 24
350510 - ER4K
350512 - ..
350513 - On 131017 1000 doctor explained patient history of intermittant and
350514 - mild peripheral neuropathy that correlates with persistent elevated T
350515 - Bilirubin in lab on 131015, ref SDS 32 015M, and further reported with
350516 - vitals, diet and exercise since prior meeting at VA on 130603, see
350517 - case study on 120101 0900, ref SDS 14 X14N, suggests intervention is
350518 - not required at this time to improve recovery from side effects taking
350519 - Rosuvastatin. ref SDS 35 LV5J
350521 - ..
350522 - On 131017 1000 VA medical chart Progress Notes assessment report
350523 - doctor concerned about chronic hyperbilirubinemia. ref SDS 35 PSXT
350524 -
350525 - [On 140211 0133 letter to medical team at SFVA Med Center
350526 - for agenda to prepare for meeting on 140213, notifies that
350527 - total bilirubin and potassium are elevated in VA lab, and
350528 - Labcorp reports these blood elements are stable.
350529 - ref SDS 50 TV5F
350531 - ..
350532 - [On 140508 1133 follow up lab by Labcorp shows Total
350533 - Bilirubin 1.3 elevated, but improved only slightly above
350534 - range. ref SDS 54 015M
350536 - ..
350537 - 2. Potasium K 5.4 Elevated above range......... ref SDS 0 ZG5O
350538 -
350539 - Doctor Egan was concerned last year about potasium (K) rising
350540 - above range for good health. He explained potasium effects
350541 - electrical signals to the heart, and so has significance for
350542 - CVD, reported during meeting at VA on 121206 0900. ref SDS 25
350543 - 6K56
350545 - ..
350546 - At that time on 121206, the doctor cited medication conflicts
350547 - as possibly causing elevated potasium. ref SDS 25 FI7L Doctor
350548 - Egan further considered dehydration (urination) caused by
350549 - Rosuvastatin may have skewed lab results for electrolytes on
350550 - 121130, and so ordered re-test. ref SDS 25 6K4J
350552 - ..
350553 - On 121212 0941 re-test lab reported Glucose 111, sodium 139,
350554 - and potasium (K) 4.6, all within range, ref SDS 26 KK9M,
350555 - correcting errors noted by Doctor Egan during meeting at VA on
350556 - 121206 0900. ref SDS 25 6K4J
350558 - ..
350559 - At this time, there is no evident cause of dehydration that
350560 - might reconcile elevated potasium (K 5.4).
350561 -
350562 - [On 140211 0133 letter to medical team at SFVA Med Center
350563 - for agenda to prepare for meeting on 140213, notifies that
350564 - total bilirubin and potassium are elevated in VA lab, and
350565 - Labcorp reports these blood elements are stable.
350566 - ref SDS 50 TV5F
350568 - ..
350569 - [On 140430 0900 letter from Doctor Egan, Cardiology
350570 - Physician at Martinez Clinic, notes medical team did not
350571 - address elevated potassium in labs, and again notifies
350572 - that this condition represents exposure to "electrical
350573 - problems" with the heart. ref SDS 52 UV5I
350575 - ..
350576 - [On 140505 0936 Doctor Egan notified that medical team at
350577 - VA Medical Center in San Francisco was notified about
350578 - concerns on elevated potassium (K) and Total Bilirubin,
350579 - ref SDS 53 YV4L, shown in labs reported in the record on
350580 - 140203 1147. ref SDS 48 ZG5O
350582 - ..
350583 - [On 140508 1133 follow up blood test by Labcorp shows
350584 - potassium (K) 5.6 elevated above range. ref SDS 54 ZG5O
350585 -
350586 -
350587 -
350588 -
3506 -
SUBJECTS
VA Lab Lipid Cholesterol 160 Decrease with Medication Hiking 1000 Mi
4903 -
490401 - ..
490402 - LDL-C 81 LDL-P 861 LDL Size Large Hike 1000 Miles Weight Lose 15 Pounds
490403 -
490404 - Follow up ref SDS 47 IM9N, ref SDS 32 IM9N.
490405 -
490406 - Good lab results today align with increased hiking and weight loss
490407 - past 3 months, reported in case study on 120101 0900, ref SDS 14 LO5O,
490408 - and reflect changes in diet with adding minimal medication, reported
490409 - on 140202, in the same study. ref SDS 14 GH4M See analysis below
490410 - calculating LDL-P 626 based on TG/HDL ratios (see para 2 and 3),
490411 - ref SDS 0 4Z6H, calculated from Labcorp test results reported on
490412 - 140201 1159. ref SDS 47 BE6O
490414 - ..
490415 - Prior LIPID PANEL 120509 1108. ref SDS 19 IM9N
490416 - Prior LIPID PANEL 120831 1525. ref SDS 20 IM9N
490417 - Prior LIPID PANEL 130228 1140. ref SDS 28 IM9N
490418 - Prior LIPID PANEL 130529 0818. ref SDS 30 IM9N
490419 - Prior LIPID PANEL 131015 0724, ref SDS 32 IM9N
490420 - Prior LIPID PANEL Labcorp, 140201 1159, ref SDS 47 IM9N
490422 - ..
490423 - LIPIDS
490425 - ..
490426 - LIPID Panel....2014 02 03 0952 140201 131015 130529
490427 - VA Labcorp VA VA VA Labcorp
490428 - NMR LipoProfile Results Results Results Results Units Range Range
490429 - LDL
490430 - LDL-P 861.0 nmol/L < 1000
490431 - <ow < 1000
490432 - Moderate 1000 - 1299
490433 - Borderline High 1300 - 1599
490434 - High 1600 - 2000
490435 - Very High > 2000
490437 - ..
490438 - Lipids
490439 - CHOL 160 156 321 H 307 mg/dL Ref: <=200 < 200
490440 - TRIGLYC 47 68 109 85 mg/dL Ref: <=150 < 150
490441 - HDL-C 58 61 50 50 mg/dL Ref: >=40 >= 40
490442 - LDL-C 93 81 249 H 240 mg/dL Ref: <=160 < 100
490443 - LDL Dir mg/dL Ref: <=160
490444 - TRIG NF mg/dL Ref: <=150
490446 - ..
490447 - LDL and HDL Particles
490448 - HDL-P (Total) 31.4 umol/L >= 30.5
490449 - Small LDL-P < 90.0 umol/L <=527.0
490450 - LDL Size 21.3 nm > 20.5
490452 - ..
490453 - --------------------------------------------------------
490454 - ** INTERPRETATIVE INFORMATION**
490455 - PARTICLE CONCENTRATION AND SIZE
490457 - ..
490458 - LDL AND HDL PARTICLES Percentile in Reference Population
490459 - HDL-P (total) High 75th 50th 25th Low
490460 - >34.9 34.9 30.5 26.7 <25.7
490461 - ..
490462 - Small LDL-P Low 25th 50th 75th High
490463 - <117 117 527 839 >839
490465 - ..
490466 - LDL Size <- Large (Pattern A)-> <- (Pattern B) ->
490467 - 23.0 20.6 20.5 19.0
490468 -
490469 - --------------------------------------------------------
490470 - Insulin Resistance Score
490471 - LP-IR Score < 25.0 <= 45.0
490472 -
490473 - The LP-IR Score combines information from lipoprotein
490474 - particle concentration and size to give improved
490475 - assessment of insulin resistance and diabetes risk.
490476 - Small LDL-P, LDL Particle Size, HDL-Particle, and
490477 - LP-IR Score have been validated by LipoScience
490478 - but not cleared by US FDA; the clinical utility
490479 - of these test results has not been fully established.
490481 - ..
490482 - INSULIN RESISTANCE MARKER
490483 -
490484 - <--Insulin Sensitive Insulin Resistant-->
490485 - Percentile in Reference Population
490486 -
490487 - Insulin Resistance Score
490488 - LP-IR Score Low 25th 50th 75th High
490489 - <27 27 45 63 >63
490491 - ..
490492 - Comments:
490493 -
490494 - a. TEST PERFORMED BY VA MARTINEZ, 150 MUIR ROAD, MARTINEZ CA.
490496 - ..
490497 - b. Evaluation for LDL-CHO:
490498 -
490499 - RISK CATEGORY LDL GOAL
490500 - CHD and CHD risk equivalents <100 mg/dL
490501 - Multiple (2+) risk factors <130 mg/dL
490502 - 0-1 risk factor <160 mg/dL
490504 - ..
490505 - HDL Chol. greater than/equal to 60 mg/dL counts as "negative" risk
490506 - factor; its presence removes 1 risk factor from the total count.
490508 - ..
490509 - Ref: Adult Treatment Panel III (ATP III) JAMA 5/16/01 Vol. 285 #19.
490511 - ..
490512 - Ordering Provider: Vamc San Francisco
490513 - Report Released: Feb 03, 2014 @ 1232
490514 - Reporting Lab: Martinez OPC/CREC
490515 - 150 Muir Road Martinez, CA 94553 4668
490516 - Performing Lab: Martinez OPC/CREC
490517 - 150 Muir Road Martinez, CA 94553 4668
490519 - ..
490520 - Analysis....
490521 -
490522 - 1. LDL-P 861 with LDL-C 81 in Labcorp test on 140201 indicates
490523 - "concordance," with both elements low. Research indicates
490524 - healthiest cardiovascular condition occurs with lowest risk for
490525 - CVD, when lipids are "discordant," with LDL-P low and LDL-C
490526 - high, shown in the record on 131125 0005. ref SDS 40 FI3G
490528 - ..
490529 - What does "LDL-C high" mean? VA published goal for LDL-C <=
490530 - 160; Labcorp published goal LCL-C < 100. ref SDS 0 5C7M New
490531 - AHA guidelines show LDL-C < 190, reported on 131112 1422.
490532 - ref SDS 38 HT87
490534 - ..
490535 - NMR test lists LDL-P < 1600 for "borderline" CVD high risk, and
490536 - that below 1000, is "low," meaning low risk for CVD.
490537 - ref SDS 0 U45J Thus, LDL-P 861 in this test presents low risk
490538 - for CVD. Research on 131125, lists LDL-P < 700 may be a better
490539 - target to manage CVD risk. ref SDS 40 WY9H The same research
490540 - also cites LDL-P < 1000 for evaluating CVD risk, similar to NMR
490541 - test today. ref SDS 40 OQ9N
490543 - ..
490544 - When can patients be confident LDL-P < 700, 600, 200 - is low
490545 - enough to work on other aspects of daily life?
490547 - ..
490548 - 2. HDL 61 20% increase over 3 months, ref SDS 0 5C7M, enabled in
490549 - part by dropping Triglycerides 47 aligns with research
490550 - indicating these factors lower LDL-P and cause regression of
490551 - atherosclerosis plaque, reported on 131125 0005. ref SDS 40
490552 - 6S7F
490554 - ..
490555 - 3. LDL-C 68% reduction exceeds by 40% best results reported for
490556 - Atorvastatin 10 combined with Ezetimibe 10 yielding reductions
490557 - 50% in clinical trial reported by AHA, in 2002 study, shown in
490558 - the record on 131125 0005. ref SDS 40 1G7L
490560 - ..
490561 - 4. LDL-P 861 in Labcorp test on 140201 correlates with TG/HDL
490562 - ratio 68/61 = 1.11. Research indicates TG/HDL ratio correlates
490563 - to LDL-P vaulations produced by NMR testing, reported on 131125
490564 - 0005. ref SDS 40 666G
490566 - ..
490567 - 5. LDL-P 626 results from much lower TG/HDL ratio 47/58 = 0.81 in
490568 - VA test today, = 73% of Labcorp TG/HDL ratio; applying this
490569 - factor .73 x 861 = 626 - assuming straight line correlations
490570 - apply.
490572 - ..
490573 - 6. LDL-P 626 on Monday 140203, indicates strong cardiovascular
490574 - function, low risk for disease, per above analysis, ref SDS 0
490575 - RV5M, and may align with hiking 22 miles on Sunday 140202,
490576 - reported in case study on 120101 0900, ref SDS 14 GH4M, since
490577 - triglycerides are sensitive to exercise for several days.
490579 - ..
490580 - 7. Another NMR test in 2 or 3 months, possibly 2 or 3 more tests
490581 - are needed to determine reliable correlations between TG/HDL
490582 - ratios for calculating LDL-P and particle size from VA labs
490583 - that omit NMR testing, for this particular patient profile. At
490584 - that point the cost of NMR tests can be saved by doing the test
490585 - only once a year. As well, NMR testing may not be needed for
490586 - TG/HDL < 2, since this indicates small-size LDL pattern B.
490588 - ..
490589 - 8. Lipid favorable results - LDL-P 861, HDL 61, TG 68 - in NMR
490590 - test on 140201, and follow up test at VA on 140203, occurred
490591 - concurrent with...
490592 -
490593 - a. Hiking 933 miles since prior lab on 131015, reported in
490594 - case study 120101 0900, ref SDS 14 LO5O, and recommended in
490595 - research on 131125 0005. ref SDS 40 QP9F including regular
490596 - aerobic exercise to lower triglycerides, ref SDS 40 JV5O,
490597 - and raise HDL, ref SDS 40 P261 and ref SDS 40 U44L, and
490598 - also raise EPC, which together cause regression of
490599 - atherosclerosis to reduce CVD risk. ref SDS 40 8X4N
490600 -
490601 - [On 140213 0830 VA work plan in Progress Notes for
490602 - meeting on 140213 prescribes continuing exercise and
490603 - dietary regimen. ref SDS 51 E34O
490605 - ..
490606 - [On 140629 1921 follow up letter to VA on 140520,
490607 - ordering coronary CTA with calcium score, ref SDS 55
490608 - VQ48, to assess reducing level of care hiking 11
490609 - miles per day in order to reduce side effects,
490610 - ref SDS 56 UZ64; further request referral to Podiatry
490611 - for consultation to relieve metatarsalgia side
490612 - effects of prescribed care. ref SDS 56 U14H
490614 - ..
490615 - b. Weight loss - hit 165 on 140121, shown in case study on
490616 - 120101 0900. ref SDS 14 A39H Did this twice more on
490617 - 140129, and weight 164 next day on 140130. ref SDS 14 RS6K
490618 - This is continuing challenge bouncing around from over 200
490619 - in 2011, but has varied significantly.
490621 - ..
490622 - c. Low-carbohydrate diet lowers triglycerides (TG 68 in
490623 - Labcorp test, and 47 in VA lab, per above, ref SDS 0 5C7M),
490624 - which together with higher HDL (TG/HDL ratio < 2) combine
490625 - to lower LDL-P, cited in research on 131125 0005.
490626 - ref SDS 40 QP9F
490628 - ..
490629 - d. Chia seeds added to diet on 131125, reported in case study
490630 - on 120101 0900, ref SDS 14 746M, and recommended by Karen
490631 - at VA on 131121 0930. ref SDS 39 NQ37
490633 - ..
490634 - e. Orange juice added to diet on 131125, based on study
490635 - indicating HDL increase 21%, ref SDS 40 R48K, as reported
490636 - to VA in letter on 140114 0845. ref SDS 44 218O
490638 - ..
490639 - f. Atorvastatin 40 mg added on 131121, reported in case study
490640 - on 120101 0900. ref SDS 14 RN3F
490642 - ..
490643 - g. Atorvastatin 10 mg reduced 131230, and added Ezetimibe 10
490644 - mg reported in case study, ref SDS 14 6A6H
490646 - ..
490647 - Research cites studies that report Atorvastatin 10 mg +
490648 - Ezetimibe 10 mg achieves LDL < 70, and favorably changes
490649 - triglycerides and HDL, reported on 131125 0005. ref SDS 40
490650 - CO45 While low LDL < 70 conflicts with goal of
490651 - "discordance" that lowers health risk for arterialsclorosis
490652 - and CVD when LDL-P low and LDL-C high, shown in research on
490653 - 131125 0005, ref SDS 40 FI3G, even "concordant" results
490654 - today are good news.
490656 - ..
490657 - Since prior lab on 131015, until lab at VA today on 140203,
490658 - case study shows on 120101, ref SDS 14 E47L, patient has
490659 - taken...
490660 -
490661 - 1. Atorvastatin............... 1850 mg
490662 - 2. Ezetimibe.................. 340 mg
490663 -
490665 - ..
490666 - Follow up prior lipid history on 121130 0846. ref SDS 24 W25L.
490667 - ..
490668 - Small LDL LP-IR
490669 - Collection DT CHOL TRIGL HDL LDL-C LDL-P HDL-P LDL-P SIZE SCORE
490670 - 02/03/2014 09:52 160 47 58 93 ......................................... ref SDS 0 BE6O
490671 - 02/01/2014 12:31 156 68 61 81 861 31.4 < 90 21.3 < 25 ..... ref SDS 47 BE6O
490672 - 10/15/2013 08:25 321 H 109 50 249 H ......................................... ref SDS 32 BE6O
490673 - 05/29/2013 08:18 307 H 85 50 240 H ......................................... ref SDS 28 BE6O
490674 - 02/28/2013 08:39 310 H 73 47 248 H ......................................... ref SDS 28 BE6O
490675 - 11/30/2012 10:01 173 53 57 105 ......................................... ref SDS 24 BE6O
490676 - 08/31/2012 15:25 176 94 47 110 ......................................... ref SDS 20 U89N
490677 - 05/09/2012 11:24 155 76 49 94 ......................................... ref SDS 19 U89N
490678 - 02/09/2012 11:18 285 82 41 228 H ......................................... ref SDS 15 2A4G
490679 - 11/17/2011 14:27 260 84 43 200 H ......................................... ref SDS 13 2A4G
490680 - 07/27/2011 12:58 163 81 45 102 ......................................... ref SDS 9 E19L
490681 - 12/07/2010 09:17 151 41 47 96 ......................................... ref SDS 8 E19L
490682 - 07/21/2010 08:54 261 H 87 35 L 209 H ......................................... ref SDS 4 E19L
490683 - 06/10/2010 10:33 217 H 83 36 L 164 H ......................................... ref SDS 3 QV4F
490684 - * 12/14/2009 11:10 241 H 136 44 170 H ......................................... 100928 0706, ref SDS 5 VW6J
490685 - 08/13/2009 15:09 233 H 118 30 L 179 H ......................................... 100610 1046, ref SDS 3 U45G
490686 - 06/16/2006 10:59 238 H 68 32 L 192 H ......................................... 091002 0900, ref SDS 1 LJ5H
490687 -
490688 - * Lab at VA San Francisco Medical Center reported on 100928 0706.
490689 - ref SDS 5 VW6J
490691 - ..
490692 - Research on cholesterol reported on 091002 0900. ref SDS 1 2F8K
490694 - ..
490695 - On 131125 0005 research found ezetimibe (zetia) mg added to
490696 - Atorvastatin 20 mg yielded after 6 weeks significantly greater changes
490697 - to lipids than taking Atorvastatin in higher doses, e.g., 20 or 40 mg.
490698 - ref SDS 40 CO56
490700 - ..
490701 - On 131125 0005 research found discordance LDL-P low and LDL-C high
490702 - lipid panel HDL 65 TG 77 healthy patient profile with LDL 246.
490703 - ref SDS 42 MN98 Discordance with LDL-P low and LDL-C high is lowest
490704 - risk for CVD, arterialsclorosis. 131125 0005, ref SDS 40 FI3G
490706 - ..
490707 - On 131125 0005 research further found CT tests can evaluate level of
490708 - plaque build up resulting from elevated cholesterol. ref SDS 41 N73K
490710 - ..
490711 - Follow up testing can take several directions...
490712 -
490713 -
490714 - 1. Continue current regimine 3 months and perform NMR test to
490715 - determine correlation between LDL-P count and size with TG/HDL
490716 - ratio. Repeat once or twice more, per analysis above.
490717 - ref SDS 0 QV6L
490719 - ..
490720 - Patient history shows prior favorable lipid results after
490721 - initial 6 months of statin drugs, and then LDL rises (see
490722 - above, ref SDS 0 W25L, This could have indicated discordance,
490723 - which shows improving cardiovascular health and lower CVD risk.
490724 - Without NMR testing, the record is unclear.
490726 - ..
490727 - 2. Trial end Ezetimibe 10 mg and continue Atorvastatin and perform
490728 - NMR in 3 months to see if favorable lipid results remain with
490729 - less medical expense.
490731 - ..
490732 - 3. Trial end Atorvastatin 10 mg and Ezetimibe 10 mg and perform
490733 - NMR in 3 months to obtain baseline NMR results without
490734 - medication.
490736 - ..
490737 - 4. Trial current medication and reduce exercise 50% from 1000
490738 - miles to 500 miles over 3 months, i.e., about 6 miles per day,
490739 - and perform NMR test to control lipids correlation between
490740 - LDL-P count and size with TG/HDL ratio. Repeat once or twice
490741 - more, per analysis above. ref SDS 0 QV6L
490742 -
490743 -
490744 -
490745 -
490746 -
490747 -
4908 -
SUBJECTS
VA Lab Cardiac Enzymnes Creatine Kinase CK 149 Range 36 340 Measures
5503 -
550401 - ..
550402 - Rosuvastatin Switch from Simvastatin Myopathy Side Effects Decline
550403 - Simvistatin Side Effects Myopathy Muscle Pain Decline Switch to Rosuvastatin
550404 - Myopathy Muscle Pain Side Effects Simvistatin Decline Switch to Rosuvastatin
550405 -
550406 - Follow up ref SDS 47 D26G, ref SDS 32 D26G.
550407 -
550408 - Prior Cardiac Enzymes Profile on 120209 1118. ref SDS 15 D26G
550409 - Prior Cardiac Enzymes Profile on 120509 1108. ref SDS 19 D26G
550410 - Prior Cardiac Enzymes, 131015 0724, ref SDS 32 D26G
550412 - ..
550413 - This test not performed by Labcorp with blood draw on 140201...
550414 -
550415 - CARDIAC ENZYMES
550416 -
550417 - DATE 2014 02 03 0952 131015 120509
550418 - VA VA VA
550419 - PLASMA Results Results Results Units Range
550420 - CK 149 110 152 IntUnits/L 36 - 340
550421 - TRPONIN ng/ml 0 - 0.07
550422 - CK-MB ng/ml 0.6 - 3.5
550423 - MYOGLOB ng/ml 20 - 82
550425 - ..
550426 - a. TEST PERFORMED BY VAMC SACRAMENTO, 10535 HOSPITAL WAY,
550427 - MATHER CA.
550429 - ..
550430 - Research on 111013 explains Creatine Kinase CK, relates to muscle
550431 - disorders caused by cholesterol medications with statins. 111013 1404,
550432 - ref SDS 12 J54K
550434 - ..
550435 - CK lab may align with reduced side effects of muscle pain in left
550436 - shoulder.
550437 -
550438 -
550439 -
550440 -
550441 -
550442 -
5505 -
SUBJECTS
HGBA1C 5.5 Range 4.1-6.2 Diabetes Negative Laboratory Blood Test Cro
8403 -
840401 - ..
840402 - HGBA1c Diabetes Blood Test
840403 - Diabetes Blood Test HGBA1c
840404 -
840405 - Follow up ref SDS 47 9F4O, ref SDS 32 9F4O.
840406 -
840407 - Prior HGBA1c Profile on 100721 0800. ref SDS 4 IL4N
840408 - Prior HGBA1c Profile on 101207 0906. ref SDS 8 IL4N
840409 - Prior HGBA1c Profile on 131015 0724. ref SDS 32 9F4O
840411 - ..
840412 - This test not performed by Labcorp with blood draw on 140201...
840413 -
840414 - HGBA1c
840415 -
840416 - HGBA1c.........2014 02 03 0952 131015 101207
840417 - VA VA VA
840418 - BLOOD Results Results Results Units Range
840419 - HGBA1c 5.5 5.5 5.7 % 4.1 - 6
840420 - eAG 111 111 mg/dL 74.0 - 118
840422 - ..
840423 - Comments:
840424 -
840425 - b. TEST PERFORMED BY VA MARTINEZ, 150 MUIR ROAD, MARTINEZ CA.
840426 -
840427 - eAG = Calculated Estimated Average Daily Glucose and may be
840428 - easier for patients to understand than an A1c result.
840429 - Calculation: 28.7 x HGBA1c - 46.7
840431 - ..
840432 - Ordering Provider: Harkesh S. Sandhu MD
840433 - Report Released: Oct 15, 2013 @ 1309
840435 - ..
840436 - Reporting Lab: MARTINEZ OPC/CREC
840437 - 150 MUIR ROAD MARTINEZ, CA 94553-4668
840439 - ..
840440 - Performing Lab: MARTINEZ OPC/CREC
840441 - 150 MUIR ROAD MARTINEZ, CA 94553-4668
840442 -
840444 - ..
840445 - This test for diabetes was ordered by Doctor Abrams during a meeting
840446 - at the San Francisco VA Medical Center on 130227 0930. ref SDS 27 8T5L
840447 - However, it is not reported for the lab performed the next day on
840448 - 130228 1140, ref SDS 28 RP4N, nor in the follow up lab 3 months later
840449 - on 130529 0818. ref SDS 30 RP4N
840451 - ..
840452 - HGGA1c was performed previously on 101207 0906, ref SDS 8 IL4N, and 5
840453 - months earlier on 100721 0800. ref SDS 4 IL4N
840455 - ..
840456 - VA lab today shows no evidence of diabetes. Aligns with Labcorp test
840457 - on 2 days earlier showing LP-IR Score < 25.0, indicating very low risk
840458 - of diabetes, reported on 140201 1159. ref SDS 47 WR9H
840459 -
840460 -
840461 -
840462 -
840463 -
840464 -
840465 -
840466 -
8405 -