THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: October 23, 2008 10:28 PM Thursday; Rod Welch

Millie confirms work plan to start sunitinib clinical study at UCSF.

1...Summary/Objective


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CONTACTS 

SUBJECTS
Default Null Subject Account for Blank Record

0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 4 0000, ref SDS 3 0000.
040502 -
040503 -
040504 -
040506 -  ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Millie received two letters today from Doctor Rugo today.  The first
040902 - explains UCSF success evaluating status change with FNA biopsy rather
040903 - than core biopys proposed by Kaiser in several letters earlier today,
040904 - ref SDS 2 667F, and saying that the form of the biopsy is for Kaiser
040905 - to decide. ref SDS 4 4Q52  Doctor Rugo's 2nd letter saying
040906 - "...hopefully [FNA biopsy] can be done rather than core," presents a
040907 - strong statement of preference for the FNA biopsy procedure.
040908 - ref SDS 4 KY8R
040910 -  ..
040911 - Doctor Rugo's 2nd letter says that positive aspiration from the biopsy
040912 - of the left supraclavicular lymph node requires ending treatment with
040913 - cetuximab Carboplatin. ref SDS 4 D65G  The doctor relates plans to
040914 - meet with Megan tomorrow about Millie's follow on treatment.
040915 - ref SDS 4 KY7Y  This implements the doctor's work plan on 081016 to
040916 - investigate Millie's condition, and if FNA biopsy shows progression of
040917 - disease, ref SDS 1 J36R, then to start Millie on new treatment with
040918 - sinitinib clinical study. ref SDS 1 J38U
040920 -  ..
040921 - Millie sent a letter to align everyone with the goal to start
040922 - sunitinib clinical study in 2 weeks, and to maintain continuity of
040923 - treatment, so the same thing does not happen that interrupted
040924 - treatment at the end of 2004, and resulted in Millie relapsing
040925 - significantly.
040926 -
040927 -    1.  Subject: Sunitinib Clinical Study Work Plan
040928 -        Date: Thu, 23 Oct 2008 22:34:51 -0700
040938 -         ..
040939 -    3.  Doctor Rugo's letter today, ref SDS 4 D65G, implements plans at
040940 -        UCSF last week on 081016, where positive asperation was a
040941 -        trigger to start treatment in the sunitinib clincial study,
040942 -        ref SDS 1 J34U and ref SDS 1 N98G, when I return from vacation
040943 -        on 081106.
040945 -         ..
040946 -    4.  The Sunitinib study requires a CT test, ref SDS 1 J44X, which
040947 -        should be scheduled on 081107, the day after I return from
040948 -        vacation.  We are planning to discuss details tomorrow at
040949 -        Kaiser.
040951 -         ..
040952 -    5.  Doctor Rugo explains [in a letter this evening on 081023]
040953 -        status change can be determined with another FNA procedure,
040954 -        rather than core biopsy. ref SDS 4 KY8R  I understood in a call
040955 -        from Doctor Daamen earlier today that Kaiser's lab requested a
040956 -        core biopsy, ref SDS 2 W15N, and that Doctor Wong is scheduled
040957 -        to do this tomorrow at 1130a [meeting set by Doctor Daamen in a
040958 -        letter in the late afternoon], ref SDS 2 667F, prior to my
040959 -        meeting with you.
040961 -         ..
040962 -    6.  If you approve, I am willing to do another FNA biopsy for
040963 -        checking status change, as Doctor Rugo suggests [in her first
040964 -        letter today, ref SDS 4 4Q52, and more strongly in her second
040965 -        letter today. ref SDS 4 KY8R]  Please coordinate with Doctor
040966 -        Wong in Head and Neck.  Maybe there are different forms of
040967 -        FNA??
040969 -         ..
040970 -    7.  Doctor Rugo plans to discuss my case with Megan, the study
040971 -        coordinator, tomorrow.
040973 -         ..
040974 -    8.  I'll get to the Head and Neck Department a little before 1130
040975 -        tomorrow, so if Doctor Wong has time, we can complete the
040976 -        biopsy with minimum delay to my meeting with you scheduled for
040977 -        1140.
040978 -
040979 -            [On 081024 Doctor Daamen advises that Doctor Wong will
040980 -            likely not be able to see Millie before 1130, 10 minutes
040981 -            before Millie's meeting at 1140 with the primary care
040982 -            physician. ref SDS 5 4P4T
040984 -             ..
040985 -            [On 081024 Millie requested assistance from primary
040986 -            care physician on deciding the type of biopsy to test
040987 -            for status change that expands available treatments for
040988 -            cancer. ref SDS 6 579O
040990 -         ..
040991 -    9.  Thanks to everyone for collaboration to maintain continuity of
040992 -        my treatment.
040993 -
041000 -         ..
041001 -   12.  PS.  I plan to get only 1 Neupogen treatment tomorrow, and skip
041002 -        Saturday, since there will be no chemo next week.  At this
041003 -        point, I don't know how sunitnib drugs will affect NEUTS (ANC).
041004 -        We can discuss further tomorrow.
041005 -
041006 -            [On 081025 Millie decided to get the 2nd Neupogen treatment
041007 -            to boost immune system strength while vacationing on a
041008 -            cruise ship in the Caribean for 2 weeks. ref SDS 7 1M55
041009 -
041010 -
041011 -
041012 -
041013 -
041014 -
041015 -
041016 -
041017 -
041018 -
041019 -
041020 -
041021 -
0411 -