THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: August 9, 2005 07:41 PM Tuesday; Rod Welch

Millie side effects increase cancer treatments new problem.

1...Summary/Objective


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CONTACTS 

SUBJECTS
Side Effects Taxotere Chemotherapy Treatments Fingernails Discolorat
Energy Very Low Week Following Start New Treatment Cycle 6 with Taxo

0904 -
0904 -    ..
0905 - Summary/Objective
0906 -
090601 - Follow up ref SDS 16 NT3I. ref SDS 14 0000
090602 -
090603 - On 050729, Millie began the 6th cycle of treatment with Taxotere and
090604 - Xeloda (capecitabine). ref SDS 17 407N
090606 -  ..
090607 - Peeling and blistering on feet have not returned, and problems of
090608 - painful feet from walking is reduced since implementing new guidance
090609 - from the pharmacist on 050729. ref SDS 17 H45G  Both feet, however,
090610 - appear continuously very red and inflammed, so this may be an
090611 - accumulating problem about to get much worse.
090613 -  ..
090614 - In the 3rd week of the treatment cycle, which is a rest week without
090615 - 2-a-day capecitabine (Xeloda) tablets, inflammation of the feet clear
090616 - up and pain fully subsides from normal walking.
090618 -  ..
090619 - Peeling of hands has been reduced somewhat to inflammation and
090620 - crinkling of the skin.
090622 -  ..
090623 - A new problem has occurred with severe discoloration of finger nails,
090624 - and some bleeding at the finger tips along the edges of the nails.
090625 - Millie was very disappointed by this new event.  The record on 021206
090626 - reports a similar side effect following completion of chemotherapy
090627 - with Taxotere for treating the original diagnosis of breast cancer.
090628 - ref SDS 1 KVST  In this case, however, more treatment cycles have
090629 - maintained a steady level of Taxotere.
090631 -  ..
090632 - In addition, Millie has recently begun experiencing tingling in toes,
090633 - fingers, and the tip of her tounge.
090635 -  ..
090636 - Millie tried Glutamine, left over from last year when this was
090637 - recommended to arrest similar side effects of treatment with Taxol and
090638 - Avastin, reported on 040722. ref SDS 3 019A  This has not been
090639 - effective so far during this round of treatments in 2005.
090641 -  ..
090642 - As expected, Millie's energy level was very low all last week; she
090643 - took time off for vacation days to cope with the problem, and as
090644 - discussed during the meeting with the doctor on 050729. ref SDS 16
090645 - DS5J
090647 -  ..
090648 - Problem of swelling in lower legs and abdomen may be reduced this
090649 - cycle, possibly following advice of the nurse on 050708. ref SDS 12
090650 - H465
090652 -  ..
090653 - Millie renewed membership at a healthclub, also, planned on 050729,
090654 - ref SDS 16 R23O, but has not started to work out again.  Hopefully
090655 - this can get started later this week.  We visited with Mil's daughter
090656 - Pam on Sunday.  Pam was watching her son and some friends play in the
090657 - community swimming pool.  During the visit, Pam was encouraging for
090658 - her mom to ease back into activity at the club, beginning with
090659 - stretching and time on the stationary bike.  Millie talked about
090660 - taking yoga classes.
090662 -  ..
090663 - Millie's clinical condition seems to show continued improvement, with
090664 - greater softness in the left breast in addition to regression of
090665 - inflammation, following up examination by the primary care physician
090666 - on 050729, citing the examination by the surgeon on 050727.
090667 - ref SDS 15 YY7F
090669 -  ..
090670 - On Tuesday, Millie was feeling more energetic.  Called her at work,
090671 - and her voice sounded strong and enthusiastic about getting things
090672 - done.
090674 -  ..
090675 - Her feet hurt, but less badly than on prior occassions.
090677 -  ..
090678 - Actually, this 2nd week of treatment with capecitabine (Xeloda), seems
090679 - less severe than the 2nd week of treatment 5.
090680 -
090681 -
090682 -
090683 -
090684 -
090685 -
090686 -
0907 -