THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: July 29, 2005 03:30 PM Friday; Rod Welch

Millie Taxotere treatment begin 6th cycle with Xeloda at Kaiser.

1...Summary/Objective
2...Blood Counts Good Dose Chemotherapy Taxol Normal
3...CA 15-3 Drops from 54 to Below Normal at 37, Lowest Reading Ever
4...Preparation for Treatment Required One (1) Attempt to Connect Port
5...Taxotere Full Dose Blood Counts Within Targets
6...Alert Energetic After Treatment Marked Change from Prior Treatments


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CONTACTS 

SUBJECTS
1st Treatment 1st Cycle Taxotere Xeloda Capacitibine Chemotherapy Tr

0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 54 0000. ref SDS 52 0000.
040502 -
040503 -
040504 -
040505 -
040506 -
040508 -  ..
0406 -
0407 -
0408 - Progress
0409 -
040901 - Angela is the nurse today.
040903 -  ..
040904 - We visited with Vivian from the pharmacy.
040906 -  ..
040907 - Vivian, asked about side effects and whether the dose should be
040908 - adjusted again.
040910 -  ..
040911 - Millie related discussions with the primary care physician earlier
040912 - today, when side effects were reported to be accelerating, ref SDS 55
040913 - DS5J, toward levels experienced previously on 050516. ref SDS 48 AQ6G
040915 -  ..
040916 - Vivian disclosed that Kaiser follows industry practice to start
040917 - patients with a maximum dose of chemotherapy, and then adjusts down to
040918 - a level the patient can tolerate.  She explained that tolerance for
040919 - chemothereapy varies widely between patients.  To get the biggest
040920 - health improvement, doctors strive for maximum strength.
040922 -  ..
040923 - Millie noted this strategy may have helped achieve a breakthrough
040924 - making substantial progress treating IBC, reported by the doctor on
040925 - 050520. ref SDS 49 025H
040927 -  ..
040928 - Vivian suggested generous use of balm on the feet, and wear socks at
040929 - night during sleep to enable the feet to regain moisture that helps
040930 - prevent pain and blisters. listed as side effects by Zan on 050415.
040931 - ref SDS 45 H44G  The documentation Zan subitted at that time, on
040932 - 050415, also, recommended vitiman B6, and balm, ref SDS 45 YG9V, cited
040933 - by Vivian today.
040934 -
040935 -     [On 050809 reduced problems from painful feet while walking, after
040936 -     implementing Vivian's guidance. ref SDS 56 6P7F
040938 -  ..
040939 - Vivian said Millie should consult further with the primary care
040940 - physician on adjusting the dosage to moderate side effects, as was
040941 - done this morning during the meeting with the doctor. ref SDS 55 EA8H
040942 -
040943 -
040944 -
040945 -
040946 -
040947 -
040948 -
040949 -
040950 -
0410 -

SUBJECTS
Blood Tests White Cell Count Good 2nd Cycle 1st Treatment Chemothera
Urine Tests No Evident Problems
Blood Test Results Pass for Treatment

0805 -
080601 -  ..
080602 - Blood Counts Good Dose Chemotherapy Taxol Normal
080603 -
080604 - Follow up ref SDS 54 Q659, ref SDS 52 Q659.
080605 -
080606 - Millie had blood drawn this morning at 1100 by the Kaiser Chemotherapy
080607 - Clinic.  They left the connection to the port so that treatment this
080608 - afternoon is faster and easier.
080610 -  ..
080611 - Angela submitted the report showing...
080612 -
080613 -    Patient   Provider  Category   View      FR Date   To Date
080619 -     ..
080620 -    Procedure              Results             Reference Range
080622 -     ..
080623 -    Log#: 540521000022      050729 06:47 Outpa WCR Req: RA Johnson, MD
080624 -
080625 -                  ** Martinez Medical Offices **
080627 -     ..
080628 -    @CBC
080629 -    WBC x 10-3               5.4 K/uL           3.5   -     12.5
080630 -    RBC x 10-6    L         3.32 M/uL           3.60  -      5.10
080631 -    Hemoglobin    L         11.1 g/dL          11.5   -     15.0
080632 -    Hematocrit    L         32.2 %             34.0   -     46.0
080633 -    MCV                       97 fL            80.0   -    100.0
080634 -    RDW            H        19.2 %             11.9   -     14.3
080635 -    Plt x10-3              260   K/uL         140     -    400
080636 -     ..
080637 -    Neutrophils    H          82 %             50     -     70
080638 -    Lymphocytes               14 %             20     -     50
080639 -    Monocyte                   3 %              0     -     11
080640 -    Eosinophils                0 %              1     -      5
080641 -    Basophil                   1%               0     -      2
080642 -    Bands              No Report %              0     -      5
080643 -    Manual Diff?           Chemo
080645 -     ..
080646 -    CA 15-3        Test Remote Collect         -<     -     39
080648 -     ..
080649 -    Seg Neutrophils    No Report %             50     -     70
080651 -     ..
080652 -    DIFF Method         Auto Dif
080653 -    Anisocytosis       No Report+
080654 -    Macrocytes         No Report+
080655 -    Plt estimate         Adequate
080657 -     ..
080658 -    Alkaline Phos             44 U/L           38     -    126
080659 -    Bili, Tot Adult         <0.3 mg/dL        0.2     -    1.3
080660 -    Creatinine               0.7 mg/dL        0.6     -    1.2
080661 -    Phosphorus     Test Remote Collect
080662 -    Alt (SGPT)                38 U/L           11     -     66
080663 -    AST (SGOT)                46 U/L           11     -     66
080665 -     ..
080666 -    Cuomdin (Anticoag Ther WARFARIN
080667 -    PT, Patient             23.5 Sec         9.2           11.6
080668 -    PT, INR                  2.3 Ratio         2              3
080669 -
080670 -
080671 -
080672 -
080673 -
080674 -
0807 -

SUBJECTS
CA 15-3 78 Smaller Rise than 10 Points Reported on 040318

0903 -
090401 -  ..
090402 - CA 15-3 Drops from 54 to Below Normal at 37, Lowest Reading Ever
090403 -
090404 - Follow up ref SDS 54 2N5J, ref SDS 52 2N5J.
090405 -
090406 - Results is not available for CA 15-3 on the blood test today.  Angela
090407 - submitted results on the blood test for last week on 050701...
090408 -
090409 -    Log#: 540518200022      050701 06:43 Outpa WCR Req: RA Johnson, MD
090411 -  ..
090412 - Good news CA 15-3 has dropped to 37, two points below 39, and down
090413 - dramatically from 54 reported on 050611. ref SDS 51 554O  This is the
090414 - best reading Millie has ever had on this particular test in 4 years of
090415 - treatment.  She had a 39 on the test last year on 041007, ref SDS 34
090416 - 2N5J, but today is better.  There is indication of a significant
090417 - change in fortunes from the long climb that reated 105 on 050329.
090418 - ref SDS 44 PPRX
090419 -
090420 -
090421 -
090422 -
090423 -
090424 -
090425 -
090426 -
0905 -

SUBJECTS
Prepare for Treatment Connect Equipment for Port Catheter
Tagiment Dexatron Administered to Prevent Alergic Reaction to Taxol
Port Catheter Required 3 Tried to Connect Infusion Equipment Prepare

1205 -
1206 - 1341
120701 -  ..
120702 - Preparation for Treatment Required One (1) Attempt to Connect Port
120703 -
120704 - Follow up ref SDS 54 EB7J, ref SDS 52 EB7J.
120705 -
120706 - Vitals taken by Shannon...
120707 -
120708 -    Blood preasure    133  74
120709 -    Pulse              84
120710 -    Temperature        99.3
120712 -  ..
120713 - Another nurse took admin with Angela to verify Millie's identification
120714 - and treatment.
120716 -  ..
120717 - Millie explained having taken Decadron tablets according to the
120718 - prescription to take two tablets twice a day, per instructions on
120719 - 050415. ref SDS 45 8U4O
120721 -  ..
120722 - Angela gave Millie a pill for Compazine 10 prior to treatment that
120723 - reduces nausea rather than as a drip treatment to avoid allergic
120724 - reaction.
120726 -  ..
120727 - Angela made installation, per above. ref SDS 54 Q659
120729 -       ..
120730 -      Interlink System Vented Paclitaxel set
120732 -  ..
120733 - Millie's blood counts are good, so there is no requirement to take
120734 - Nupigen again to strengthen the immune system.
120735 -
120736 -
120738 -  ..
1208 -
1209 -
1210 - 1552
1211 -
121101 - Benedryl started.
121102 -
121103 -
121105 -  ..
1212 -
1213 -
1214 - 1609
1215 -
121501 - Benedryl completed.  Equipment did not beep; Angela noticed the
121502 - container was empty, and so switched to Taxotere drip treatment.
121503 -
121504 -
121505 -
121506 -
121507 -
121508 -
121509 -
121510 -
1216 -

SUBJECTS
Taxol Treatment Delayed 30 Minutes Because Lab Has Not Prepared Trea
AC Adriamycin Cytoxin Treatment Begun Today on New Regimine Replacin

1504 -
1505 - 1611
150601 -  ..
150602 - Taxotere Full Dose Blood Counts Within Targets
150603 -
150604 - Follow up ref SDS 54 4N5M, ref SDS 52 4N5M.
150606 -  ..
150607 - Taxotere started.
150608 -
150609 -
150610 -
150611 -
150613 -  ..
1507 -
1508 - 1708
1509 -
150901 - Equipment beeped indicating treatment is over.
150902 -
150903 - Taxotere treatment completed.
150905 -  ..
150906 - Saline flush was run for a few minutes.
150908 -  ..
150909 - Angela did not remove the drip treatment tube from the port, and
150910 - apply Hepren to reduce clotting, and avoid infection, because this
150911 - was done earlier today when Millie got blood drawn in the lab.
150913 -  ..
150914 - Angela did not get vitals at the end of treatment, as was done last
150915 - time.
150916 -
150917 -   Temperature......... 97.6
150918 -   Pulse............... 145 77
150919 -   Blood Pressure...... 57
150920 -
150921 -
150922 -
150923 -
150925 -  ..
1510 -
1511 -
1512 - 1714
1513 -
151301 - We went to the Pharmacy and picked up the prescriptions for...
151302 -
151303 -            Xeloda
151305 -  ..
151306 - The co-payment on these drugs was approximatley $60.  The full price
151307 - was about $1,300, saving $1,240.
151308 -
151309 -
151310 -
151311 -
151312 -
151313 -
151314 -
151315 -
1514 -

SUBJECTS
Tired Wobbly on Feet after Treatment In Asleep by 1900
Tired Wobbly on Feet after Treatment Asleep by 1900 Not Today After

1704 -
1705 - 1537
170601 -  ..
170602 - Alert Energetic After Treatment Marked Change from Prior Treatments
170603 -
170604 - Follow up ref SDS 54 F54N, ref SDS 52 F54N.
170605 -
170606 - Millie seemed okay after treatment today.  No immediate wobbliness.
170607 - She was okay to drive, and seemed alert the rest of the day.
170609 -  ..
170610 - This seems unusual because Benedryal is part of the protocol for
170611 - Taxotere, per above. ref SDS 45 064F  Previously, when treated with
170612 - Bendryl and Taxotere, Millie has been noticably wobbly and unsteady
170613 - on her feet, and retired early to bed, reported on
170614 -
170615 -
170616 -
170617 -
170618 -
170619 -
170620 -
170621 -
170622 -
1707 -