THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: June 3, 2002 11:15 AM Monday; Rod Welch

Meeting at Kaiser CA 15-3 rises and PET, chemotherapy treatment changed.

1...Summary/Objective
2...CA 15-3 117 Jumps Significantly Above Normal Exepected for Recovery
3...Treatment Changed from AC to Taxotere


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CONTACTS 

SUBJECTS
PET Scan Test Scheduled for 020529 0700
PET Scan Test to Investigate CA 15-3 at 81 and Cyst 1 CM on Liver
Cancer Discoverd Uner Millie's left Arm Where Lymph Nodes Were Previo
CA 15-3 from Blood Test on 020511 is 117 Elevated from 81 Indicating
Chemotherapy Not Effective New Blood Test Orderded Changed Treatment
Brain MRI Test Ordered because PET Scan Did Not Include Brain
PET Test Shows Cancer Lump Under Arm Left Side Where Lymph Nodes Ali

1309 -
1309 -    ..
1310 - Summary/Objective
1311 -
131101 - Follow up ref SDS 17 0001 ref SDS 18 0000.
131102 -
131103 - The doctor reviewed results of PET scan test on 020529 showing
131104 - evidence of metastasis under the left arm where surgery was performed
131105 - on 020312 and on 020327, and where Millie has complained of continuing
131106 - discomfort.
131108 -  ..
131109 - He described the condition as localized to the arm pit area, also,
131110 - called the "axilla," rather than a condition of "distant metastasis,"
131111 - within the meaning reviewed on 020321. ref SDS 3 FX5H
131112 -
131113 -     [On 020726 patient reports discomfort and lump have ended after
131114 -     changing chemotherapy treatments. ref SDS 24 YO52
131116 -      ..
131117 -     [On 030109 follow up PET scan test performed on 021218 to evaluate
131118 -     results of chemotherapy and radiation treatment found regional
131119 -     mild diffuse uptakes, which were not diagnosed as treatable cance.
131120 -     ref SDS 27 5R4J
131122 -      ..
131123 -     [On 030710 meeting receive CT test performed on 030626; reports of
131124 -     regional persistant dermal (skin) thickening left breast; notes
131125 -     that invasion of the dermal lymphatics from known breast cancer
131126 -     can present similarly. ref SDS 28 VM7I
131127 -
131129 -  ..
131130 - CA 15-3 117 Jumps Significantly Above Normal Exepected for Recovery
131131 -
131132 - The doctor discussed implications of the CA 15-3 cancer marker having
131133 - elevated to 117 today from 81 reported on 020430. ref SDS 15 7N5H  He
131134 - feels this is consistant with the PET scan showing traces of cancer
131135 - forming a lump in the left arm pit, and reflects the pathology report
131136 - on 020321 showing flow out of a lymph node capsule from the biopsy
131137 - taken on 020312. ref SDS 3 JE8H,
131139 -  ..
131140 - The doctor expects that changing chemotherapy today, in combination
131141 - with radiation treatments should destroy the cancer, and this should
131142 - bring the CA 15-3 marker down.
131143 -
131144 -      [On 020607 next blood test shows CA 15-3 has dropped slightly to
131145 -      108. ref SDS 19 X67F
131147 -       ..
131148 -      [On 070301 similar issue of possible expanding disease with
131149 -      rising (uncertainty) about CA 15-3 56 considered at UCSF during
131150 -      clinical trial. ref SDS 32 OL5M and further explained.
131151 -      ref SDS 32 QN3F
131152 -
131154 -  ..
131155 - Treatment Changed from AC to Taxotere
131156 -
131157 - The doctor is concerned that PET scan and CA 15-3 testing indicate
131158 - today, that current treatment with two (2) cycles so far of Adriamycin
131159 - Cytoxan (AC) set initially for Millie to get four (4) treatments with
131160 - AC, on 020405, ref SDS 5 6SWS, is not effective for Millie.  He was
131161 - very disappointed that this "gold standard" therapy is evidently
131162 - resisted by Millie's cancer.  The doctor decided to change chemtherapy
131163 - to use Taxotere for the next (3rd) treatment.  He explained that
131164 - Taxotere is another standard protocol for treating breast cancer.
131165 -
131166 -     [On 020610 Millie began treatment with Taxotere. ref SDS 20 LO9N
131168 -      ..
131169 -     [On 020708 patient completes phase 1 of chemotherapy consisting of
131170 -     4 cycles, the first two with AC, and the next 2 with Taxotere;
131171 -     meets with radiologist at Mt Diablo to plan radiation treatments.
131172 -     ref SDS 23 TV4I
131174 -      ..
131175 -     [On 020924 radiation treatment ends; start 2nd phase of
131176 -     chemotherapy with Taxotere. ref SDS 25 0J7H
131178 -      ..
131179 -     [On 021204 4th and final dose of Taxotere for phase II adjuvant
131180 -     treatment. ref SDS 26 F5Z5
131182 -      ..
131183 -     [On 040812 doctor recommends against PET scan testing to evaluate
131184 -     scope of new problem after IBC diagnosed, and patient treated with
131185 -     chemotherapy under a trial protocol for Avastin and Taxol, with
131186 -     side effects beginning to accumulate and conflicts occurring in CT
131187 -     tests. ref SDS 29 7R9H
131189 -      ..
131190 -     [On 041005 dilemma CA 15-3 shows steady rise indicating failed
131191 -     treatment, but CT test report shows no cancer (adenopathy), so
131192 -     deciding course of treatment is problematic. ref SDS 30 N23N
131194 -      ..
131195 -     [On 050204 similar pattern examination shows worsening symptoms of
131196 -     IBC after two (2) treatments with AC; prescribe continuing AC
131197 -     based on record today of eventual improvement. ref SDS 31 J544
131199 -  ..
131200 - The doctor ordered another blood test, and asked Millie to call on
131201 - 020607 about results of blood test to see trend on CA 15-3 marker.
131203 -  ..
131204 - The doctor ordered an MRI on the head to look for metastasis in the
131205 - brain, because the PET scan test did not include the head.
131206 -
131207 -      [On 020617 MRI test on brain at Kaiser. ref SDS 22 0001
131208 -
131209 -      [On 070301 similar issue of possible expanding disease with
131210 -      rising (uncertainty) about CA 15-3 considered at UCSF during
131211 -      clinical trial. ref SDS 32 OL5M and further explained.
131212 -      ref SDS 32 QN3F
131214 -       ..
131215 -      [On 070308 cancer marker CA 15-3 dropped dramatically at UCSF
131216 -      which aligned with subsiding IBC intensity; treatment was not
131217 -      changed. ref SDS 33 FO6H
131218 -
131219 -
131220 -
131222 -  ..
1313 -
1314 -
1315 - 1313
1316 -
131601 - After the meeting with the doctor, Millie went to the Lab and had
131602 - another blood test.
131603 -
131604 -     [On 020610 CA 15-3 marker dropped from 117 to 108 for blood test
131605 -     taken today 020603. ref SDS 20 G74J
131607 -      ..
131608 -     [On 020614 after another blood test a week later, CA 15-3 dropped
131609 -     to 65. ref SDS 21 0001
131610 -
131611 -
131612 -
131613 -
131614 -
131615 -
131616 -
131617 -
131618 -
131619 -
131620 -
131621 -
1317 -
1318 -