THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rod@welchco.com


S U M M A R Y


DIARY: October 5, 2015 08:00 AM Monday; Rod Welch

VA meeting with Lana in Wound Clinic reviewed recovery debridement surgery left leg.

1...Summary/Objective


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CONTACTS 

SUBJECTS
Default Null Subject Account for Blank Record                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
0403 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0403 -    ..
0404 - Summary/Objective                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
0405 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
040501 - Follow up ref SDS 7 0000. ref SDS 6 0000.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040502 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040503 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040504 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040505 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040506 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040508 -  ..
0406 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0407 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0408 - Progress                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0409 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
040901 - Meeting in Clinic Module 2...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
040902 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040903 -                           Svetlana Nakamura, RN, WCC, OMSN                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
040904 -                           United States Department Veteran's Affairs                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040905 -                           Medical Center                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
040906 -                           Nursing Service                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
040907 -                           Building 200 Room GA-157                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
040908 -                           Clinic Module 2                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
040909 -                           4150 Clement Street                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
040910 -                           San Francisco, CA  94121                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
040911 -                           415 221 4810  ext 4772                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
040912 -                           Cell 415 260 3456                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
040913 -                           svetlana.nakamura@va.gov                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
040915 -  ..
040916 - Lana removed the dressing she placed last Thursday on 151001 1200.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
040917 - ref SDS 7 X67K                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040919 -  ..
040920 - Lana advised that the wound today is significantly improved from last                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040921 - Thursday.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
040923 -  ..
040924 - Reported hiking 11 miles yesterday, which evidently increases                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
040925 - recovery, based on Lana's findings this morning.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
040927 -  ..
040928 - Lana seemed to indicate that "undermining" of the wound has improved                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040929 - but remains major problem.  She explained again today that further                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
040930 - debridement is needed for the wound to heal.  She described this in                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040931 - part as removing dead skin.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
040933 -  ..
040934 - Lana discussed doing this again today, using the scaple method which                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040935 - she used last Thursday on 151001 1200. ref SDS 7 WW4I   We discussed                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
040936 - using standard of care performing debridement with conscious sedation                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040937 - that avoids excessive pain.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
040939 -  ..
040940 - Lana is meeting with Doctor Stewart tomorrow.  She will recommend the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040941 - Surgery Department schedule a procedure to perform additional                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
040942 - debridement using conscious sedation, rather than perform this work                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040943 - without sedation, and rather than attempt to use local anesthetic                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
040944 - applied with injections around the perimeter of the wound.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
040946 -  ..
040947 - Thanked Lana for working to have debridement performed with conscious                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040948 - sedation.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
040950 -  ..
040951 - Scheduled next meeting on Thursday, 151008 1200.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
040952 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040953 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040954 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040956 -  ..
0410 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0411 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0412 - 0842                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
0413 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
041301 - After meeting with Lana went to ER and reported problems with right                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041302 - wrist.  This began a long series of radiology imaging, and then                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041303 - treatment with a form of removable cast, explained in another record.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041304 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041306 -  ..
0414 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0415 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0416 - 1028                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
0417 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
041701 - Received call on cell phone, while talking to the Radiology                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
041702 - Department on the 2nd floor of building 200.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
041704 -  ..
041705 - The caller was a assistant for Doctor Stewart, and advised a meeting                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041706 - is scheduled tomorrow at 1315 with the doctor in Module 2 Clinic.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041708 -  ..
041709 - Later, after returning to the ER on the ground floor, saw Lana walking                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041710 - through the main VA Medical Center lobby.  Asked if she was aware of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041711 - the meeting tomorrow with Doctor Stewart - is this the meeting which                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041712 - Lana earlier this morning planned to schedule when she sees Doctor                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041713 - Stewart tomorrow?                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041715 -  ..
041716 - Lana said it is.  Instead of waiting until tomorrow to discuss the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041717 - matter with Doctor Stewart, she called Isagani and requested they                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041718 - schedule the meeting with Doctor Stewart.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
041719 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041721 -  ..
0418 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0419 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0420 - 1102                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
0421 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
042101 - Met by accident in the hallway, Doctor Judith Wisneski.  Have seen her                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042102 - over the past years talking with Doctor Stewart in the hallways, but                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042103 - have never been introduced.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
042105 -  ..
042106 - None-the-less she knew my name.  Doctor Wisneski advised that she                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042107 - works in Cardiology and is aware of the meeting scheduled with Doctor                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042108 - Simpson on 151014.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042110 -  ..
042111 - This meeting today, took place in building 300 ground floor, near the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042112 - door to the stairs at the main elevators near the Clinic Modules.  The                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042113 - doctor had her back to the door, and while we talked somone opened the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042114 - door abruptly, striking her in the back, including her head.  Of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042115 - course she was startled, and immediately said she must lay down to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042116 - recover from this blow.  Doctor Wisneski went through door, and I                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042117 - followed to render assistance.   However, she leaned against the wall                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042118 - of the stair well, and continued discussion.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
042120 -  ..
042121 - Later was told that Doctor Wisneski is Chief of Cardilogy at the VA.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042123 -  ..
042124 - We had a long discussion in the stairwell, perhaps 30 minutes, about                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042125 - performing coronary CT angiography (CCTA) with calcium score for the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042126 - purpose of...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
042127 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
042128 -    1.  Evaluate level of atherosclerotic plaques following CABG +4 on                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042129 -        091022 0700. ref SDS 2 JF9K                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
042131 -         ..
042132 -    2.  Low levels of atherosclerotic plaques shown by CCTA with low                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042133 -        calcium score provides standard of care testing response to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042134 -        treatment with extended endurance exercise through hiking 11                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042135 -        miles per day, 300 miles per month at the rate of 13 - 17                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042136 -        minutes per mile, and over the past 4 years which raised HDL                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042137 -        from 30 to 70, as shown in spreadsheet previously submitted to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042138 -        Doctor Rao...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042139 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
042140 -              F:\05\00003\SM\CC\BNKG\120216cc\130101cc\hiking_miles_3.xlsx                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
042142 -         ..
042143 -        General summary of hiking correlated with improved HDL and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042144 -        Triglycerides is shown in case study of patient history on                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042145 -        140101 0600. ref SDS 4 TTQS (see line 107069)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
042147 -         ..
042148 -    3.  Low levels of atherosclerotic plaques shown by low calcium                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042149 -        score may occur from rapid regression and repair of lesions in                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042150 -        the endothelium lining of blood vessels with high levels of HDL                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042151 -        (> 60) cholesterol and EPCs, both produced with extended                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042152 -        endurance exercise through hiking 11 miles per day, 300 miles                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042153 -        per month.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042155 -         ..
042156 -    4.  Low levels of atherosclerotic plaques shown by low calcium                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042157 -        score supports reduced reliance on statin drug treatments,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042158 -        since atherosclerotic plaques take years to regenerate.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
042160 -         ..
042161 -    5.  Low levels of atherosclerotic plaques shown by low calcium                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042162 -        score that supports reduced reliance on statin drug treatments,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042163 -        thereby reduces onerous side effects of statin drugs.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
042165 -         ..
042166 -        Reduced dizziness increases effectiveness performing daily                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042167 -        work.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
042169 -         ..
042170 -        Reduced urination reduces dehydration, which reduces feet                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042171 -        injuries of blistering, scaling, peeling, bleeding.  Healthy                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042172 -        feet enables more hiking to increase HDL and EPCs maintaining                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042173 -        low levels of atherosclerotic plaques, lowering risks of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
042174 -        negative cardiovascular events, and thus extending chances of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042175 -        longevity with a quality of life worth living.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042177 -         ..
042178 -    6.  Low levels of atherosclerotic plaques shown by low calcium                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042179 -        score supports reduced level of effort performing extended                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042180 -        endurance exercise through hiking, perhaps to 4 or 5 miles per                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042181 -        day, thus enabling investing 1 - 2 hours saved per day in                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042182 -        other necessities.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
042184 -  ..
042185 - The doctor was aware of pending meeting with Doctor Simpson scheduled                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042186 - on 151014 0900.  She noted the doctor feels this upcoming meeting is                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042187 - unnecessary, and that nothing can be accomplished.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042189 -  ..
042190 - Doctor Wisneski was sympathetic with objectives for reducing side                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042191 - effects of statin medications, in this case mainly dizziness and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042192 - frequent urination, which in turn causes dehydration that injures the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042193 - feet, preventing hiking to raise HDL.  She suggested continuing to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042194 - take statins but at reduced levels, e.g., here reducing Atorvastain 10                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042195 - mg and Ezetimibe 10 mg to 5 mg.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
042197 -  ..
042198 - Doctor Wisneski further proposed changing use of statins from daily to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042199 - every other day, thus lowering the concentration in order to reduce                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042200 - side effects.  This would be trial and error finding levels of statins                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042201 - that maintain favorable lipids with minimum side effects.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
042203 -  ..
042204 - The doctor asked about patient history taking statins?                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042206 -  ..
042207 - Reported bad side effects with Simvastatin beginning in 2010, and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042208 - later with Rosuvastatin beginning in 2012.  Since 131015, have been                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042209 - taking Atorvastatin and Ezetimibe.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042211 -  ..
042212 - Doctor Wisneski seemed say the medical team cannot support standard of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042213 - care in this case because there is no protocol for using coronary CT                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042214 - angiography tests with calcium score to test for response to treatment                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042215 - with extended endurance training hiking 11 miles per day and 300 miles                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042216 - per month.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
042218 -  ..
042219 - The doctor seemed to mention that some years ago UCSF had a protocol                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042220 - for testing response to treatment with extended endurance exercise.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042221 - She further indicated that testing only 1 person would not justify                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042222 - publishing results.  She noted there would be difficulty attracting                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042223 - people to participate in a trial of extended endurance exercise at                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042224 - levels 7 - 8 miles per day and even 250 miles per month required to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042225 - raise HDL above 60, sufficient to regress atherosclerotic plaques.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042227 -  ..
042228 - The implication seemed to be that if other patients choose not to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042229 - invest effort for regressing athersclerotic plaques to extend                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
042230 - longevity, this justifies not testing to see if benefits in this case,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042231 - as set out above, ref SDS 0 HE5Y, support reducing drug side effects                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042232 - by reducing treatment with statin medications.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
042234 -  ..
042235 - Doctor Wineski at one point noted patients are free to stop taking                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042236 - statin drugs to control atherosclerotic plaques at any time, so there                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042237 - is no need to perform coronary CT angiography test to determine that                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042238 - former high concentrations of atherosclerotic plaques have been fully                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042239 - regressed, which justifies ending treatment with statin drugs, and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042240 - also reducing treatment time performing extended endurance exercise,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042241 - thus reducing wear and tear on the body, i.e., side effects of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
042242 - endurance training. (see point 6, ref SDS 0 IL4I)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042244 -  ..
042245 - In other words, deciding to pause treatment with statins seems similar                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042246 - to pausing chemotherapy so cancer patients can avoid debilitating side                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042247 - effects of treatment, when testing shows cancer has been regressed,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042248 - shown by Millie's case fighting stage 4 cancer for nearly 10 years.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042250 -  ..
042251 - The doctor also explained that even if coronary CT angiography (CCTA)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042252 - testing found even a single 10% lesion, this would not justify                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
042253 - reducing statin drug treatment, because the next day after the test,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042254 - that single 10% lesion could become a 100% blockage.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042256 -  ..
042257 - Advised this theory has not been encountered in cardiology and lipid                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042258 - management literature, reviewed on 131125 0005. ref SDS 3 JV5O                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042260 -  ..
042261 - There was no discussion today of how taking statin treatments would                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042262 - avoid a catostrphic event of a 10% lesion suddenly expanding into a                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042263 - 100% blockage.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
042265 -  ..
042266 - Doctor Wineski seemed to say at one point that while coronary CTA is                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042267 - not a reliable test for evaluating regression of atherosclerotic                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042268 - plaques, this can be evaluated effectively with conventional and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042269 - invasive cardiac catheterization angiogram testing.  This procedure                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042270 - was performed by Doctor Shunk in this case on 091021 0716. ref SDS 1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
042271 - 7L43                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042273 -  ..
042274 - Indicated objective to forego invasive procedures.   There was not                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042275 - time today for discussing why finding no atherosclerotic plaques with                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042276 - invasive procedures is any more helpful than making the same finding                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042277 - with radiology methods.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
042279 -  ..
042280 - Further suggested that the meeting with Doctor Simpson scheduled for                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042281 - 151014, can be cancelled, based on extensive time Doctor Wineski has                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042282 - generously granted today presenting the views of the Cardiology                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
042283 - Department.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
042285 -  ..
042286 - Doctor Wineski seemed to indicate the meeting should take place.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042288 -  ..
042289 - We did not discuss periodic treatment "holidays," as occurs in                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
042290 - oncology practice treating cancer.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
042292 -  ..
042293 - Thanked Doctor Wisneski for sharing ideas on managing atheroslclorsis                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042294 - risks.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
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0424 -