THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rod@welchco.com
S U M M A R Y
DIARY: May 15, 2014 08:43 PM Thursday;
Rod Welch
VA letter favorable results NMR lipid test and need follow up electrolytes.
1...Summary/Objective
2...VA Notified Excellent Results on Lipids Need Follow Up Electrolytes
3...Potassium Elevated Doctor Egan Cites Electrical Problems for Heart
4...Lab Results Influenced Extended Exercise Hiking 22 Miles then 11 Miles
5...Weight 163 Lowest in 30 Years Resolve Metabolic Syndrome
6...VA Order Electrolyte Chem Lab Order Check After Re-hydration
7...Medication Side Effects Atorvastatin Ezetimibe
8...Dizziness Increase Urination Peripheral Neuropathy
9...Coronary CTA Assess Regression Atherosclerosis 5-years Post CABG +4
10...HDL 20 Increase with Orange Juice Aligns Patient History
11...Orange Juice Study Aligns Patient History HDL 67 Increase 20%
12...EPC Add to Labs Assess Potential Regression Atherosclerosis
13...VA Commend Good Care Shown by Excellent Results
..............
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CONTACTS
SUBJECTS
VA Lab Lipids Submit Labcorp Results to Prepare for Meeting on 14051
1503 -
1503 - ..
1504 - Summary/Objective
1505 -
150501 - Follow up ref SDS 58 0000. ref SDS 56 0000.
150502 -
150503 -
150504 -
150506 - ..
1506 -
1507 - Progress
150801 - ..
150802 - VA Notified Excellent Results on Lipids Need Follow Up Electrolytes
150803 -
150804 - Follow up ref SDS 58 IM9N, ref SDS 56 IM9N.
150805 -
150806 - Letter to VA medical team says...
150807 -
150808 - 1. Subject: Lipid Profile Improved
150809 - Date: 2014-05-15 21:19
150817 - ..
150818 - 2. Labcorp results last week on 140508, show LDL-P dropped to 851
150819 - and HDL increased to 67. [...shown in record consolidating
150820 - Labcorp test on 140508 with VA lab yesterday on 140514 0950.
150821 - ref SDS 58 IM9N...]. Previously, when labs showed major
150822 - improvement the next lab showed worsening conditions. [...see
150823 - Patient Lipid History, ref SDS 56 W25L...]. This report breaks
150824 - that cycle, showing continuing good results. ref SDS 56 U45J
150825 -
150826 - [On 140520 0732 letter to VA notifies Doctor Alba confirm
150827 - work plan to continue statin medication with Atorvastatin
150828 - 10 mg and Ezetimibe 10 mg despite rising peripheral
150829 - neuropathy because symptoms at this time are mild, and
150830 - lipid results are favorable. ref SDS 62 4U4F
150832 - ..
150833 - 3. Yesterday, after talking with you, I got results from ROI on VA
150834 - lab at the Medical Center, so no need for you to submit it.
150835 - While VA does not report LDL-P, since VA metrics on HDL and TG
150836 - align with Labcorp, ref SDS 56 5C7M, LDL-P 851 and pattern A
150837 - (large) LDL particle size 21.2 seem like good numbers to assess
150838 - lipid management and plan next steps.
150840 - ..
150841 - 4. Have to admit some confusion with format of new VA lab report
150842 - that presents multiple values (a and b). [...shown on 140514
150843 - 0950, ref SDS 58 5C7M...]. Some elements have no values.
150845 - ..
150846 - Later considered that VA may have run two tests on lipids to verify
150847 - exceptionally good numbers that "seemed too good to be true," added
150848 - explanation to the record on 140514 0950. ref SDS 58 864H
150849 -
150850 -
150851 -
150852 -
150853 -
1509 -
SUBJECTS
VA Lab Lipids Submit Labcorp Results to Prepare for Meeting on 14051
2903 -
290401 - ..
290402 - Potassium Elevated Doctor Egan Cites Electrical Problems for Heart
290403 -
290404 - Letter to VA continues...
290405 -
290406 - 5. Met with Doctor Egan in Cardiology at Martinez Clinic on
290407 - 140430. After the meeting, the doctor wrote a letter noting
290408 - again that potassium (K) was elevated in lab on 140203, and
290409 - cited risk of "electrical problems" for CAD patients (see line
290410 - 392120. ref SDS 54 UV5I
290412 - ..
290413 - 6. Notified Doctor Egan that follow up lab was scheduled in 2
290414 - weeks and that concerns on potassium and bilirubin would be
290415 - addressed in the meeting with you at the Medical Center on
290416 - 140519. [...referencing letter to Doctor Egan on 140430 0900.
290417 - ref SDS 54 YV5T...]
290419 - ..
290420 - 7. As you can see, on 140508, Labcorp reported potassium (K) high,
290421 - increased to 5.6. For some reason the lab at the VA yesterday
290422 - did not report potassium, nor glucose, sodium - actually most
290423 - of the electrolyte panel. ref SDS 56 ZG5O Both Labcorp and VA
290424 - report bilirubin still high. VA shows T Bili 2.2, nearly
290425 - double the range and up from 2.1 in lab 3 months ago. [...
290426 - shown on 140508 1133. ref SDS 56 015M...]. This might be an
290427 - issue of liver function in relation to medication, though we
290428 - are currently low dose with Atorvastatin 10mg and Ezetimibe
290429 - 10mg.
290430 -
290431 - [On 140518 2120 follow up letter reports that since VA has
290432 - not issued notice to do Electrolyte (Chem Profile) lab to
290433 - check glucose, sodium and potassium, customer will not
290434 - report lab for blood draw prior to meeting with VA at
290435 - Medical Center in San Francisco on 140519 0830. ref SDS 59
290436 - DV4M
290437 -
2905 -
SUBJECTS
Default Null Subject Account for Blank Record
3003 -
300401 - ..
300402 - Lab Results Influenced Extended Exercise Hiking 22 Miles then 11 Miles
300403 -
300404 -
300405 - 8. As well, lab results might be influenced by exercise, e.g.,
300406 - dehydration, from hiking 22 miles the day before both labs, and
300407 - 11 miles the morning before both labs.
300408 -
300409 -
3005 -
SUBJECTS
Default Null Subject Account for Blank Record
3103 -
310401 - ..
310402 - Weight 163 Lowest in 30 Years Resolve Metabolic Syndrome
310403 -
310404 -
310405 - 9. On 140513, weight dropped to 163, lowest in 30 years, after
310406 - hiking another 1000 miles since prior labs in February, see
310407 - case study (see line 105212. [...shown on 120101 0900,
310408 - ref SDS 15 ZU5G
310410 - ..
310411 - This level of endurance exercise that aids weight control, also
310412 - lowers triglycerides, cited in research on 131125. ref SDS 43 U44L
310414 - ..
310415 - The record hiking 1000 miles during the past cycle is shown in the
310416 - study at line 105312 for the record on 120101 0900, ref SDS 15 6Q5G,
310417 - and is cited to reconcile improved labs in the record on 140514 0950.
310418 - ref SDS 58 I17G
310420 - ..
310421 - This implements the doctor's prescription for regression of
310422 - atherosclerosis by managing cholesterol with weight loss to 165 or
310423 - even 160 through physical activity hiking 11 miles per day, presented
310424 - during the meeting at the VA Medical Center in San Francisco on 131219
310425 - 0930, ref SDS 44 A56N,
310426 -
310427 -
310428 -
310429 -
310430 -
3105 -
SUBJECTS
Default Null Subject Account for Blank Record
3203 -
320401 - ..
320402 - VA Order Electrolyte Chem Lab Order Check After Re-hydration
320403 -
320404 -
320405 - 10. A year or so ago during a meeting on 121206, Doctor Egan
320406 - noticed elevated glucose, sodium and potassium. Rosuvastatin
320407 - causing increased urination was ended, and the doctor ordered
320408 - retest a few days later. We paused hiking to further reduce
320409 - dehydration. As you can see, the 2nd lab showed the numbers
320410 - all fell back within range, reported on 121212 (see line 0408.
320411 - ref SDS 27 X45G
320413 - ..
320414 - 11. Please let me know if you want another electrolyte panel to
320415 - double check these issues. We could do the blood draw next
320416 - Monday at 0700 (assuming lab is open at that time). Results
320417 - should be posted for review during our meeting at 0800.
320418 -
320419 - [On 140518 2120 follow up letter reports that since VA has
320420 - not issued notice to do Electrolyte (Chem Profile) lab to
320421 - check glucose, sodium and potassium, customer will not
320422 - report lab for blood draw prior to meeting with VA at
320423 - Medical Center in San Francisco on 140519 0830. ref SDS 59
320424 - DV4M
320426 - ..
320427 - [On 140518 0920 at 2242 Doctor Alba notifies customer to
320428 - defer follow up chem profile (electrolyte) labs to verify
320429 - glucose, sodium and potassium elevated in Labcorp Lab on
320430 - 140508, responding to Doctor Egan's request based on
320431 - potential for potassium to cause heart problems.
320432 - ref SDS 59 NY4F
320434 - ..
320435 - [On 140520 0732 letter to Doctor Alba asking if order has
320436 - been filed for supplemental lab testing Electrolyte panel
320437 - (Chem Profile), as planned in the meeting on 140519, and
320438 - requested by Doctor Egan, so that blood draw can be done at
320439 - VA Medical Center in San Francisco. ref SDS 62 4U87
320441 - ..
320442 - 12. Alternatively, a full electrolyte (Chem) profile might be done
320443 - using the blood draw yesterday, to cross check Labcorp, and get
320444 - the numbers in the VA system? Notice VA lab reports blood
320445 - "SLIGHTLY ICTERIC SPECIMEN /HN" and for lipids "SLIGHTLY
320446 - Hemolyzed specimen /HN".
320447 -
320448 -
3205 -
SUBJECTS
Default Null Subject Account for Blank Record
4403 -
440401 - ..
440402 - Medication Side Effects Atorvastatin Ezetimibe
440403 - Dizziness Increase Urination Peripheral Neuropathy
440404 -
440405 -
440406 - 13. Only evident side effects from Ezetimibe is slight dizziness in
440407 - past month when laying down and turning my head left or right.
440408 - Don't recall this occurring past few days, so issue seems de
440409 - minimus. There may also be increased urination the past month
440410 - or so, but this is hard to track. Seem to be getting up a lot
440411 - during the night, as occurred with Rosuvastatin, but could be
440412 - imagination - not sure yet.
440414 - ..
440415 - Side effects Atorvastatin listed on 130603 0930. ref SDS 33 PC6O
440417 - ..
440418 - Side effects of Ezetimibe are listed on 131125 0005. ref SDS 43 YA7F
440419 -
440420 - [On 140518 2120 letter to VA notify Doctor Alba that side
440421 - effects of statin medications - dizziness has subsided;
440422 - urination and peripheral neuropathy have increased.
440423 - ref SDS 59 DV5S
440424 -
440425 -
440426 -
440427 -
4405 -
SUBJECTS
Default Null Subject Account for Blank Record
4503 -
450401 - ..
450402 - Coronary CTA Assess Regression Atherosclerosis 5-years Post CABG +4
450403 -
450404 -
450405 - 14. While on site yesterday, visited Radiology Department. The VA
450406 - Medical Center supports coronary CTA studies to assess
450407 - regression of plaque toward evaluating CVD risk and course of
450408 - care. This provides a baseline condition in light of rising
450409 - cholesterol the past year, prior to recent dramatic decline.
450410 - Research indicates plaque can regress quickly with restoration
450411 - of endothelial function (see study on 131125 (see line OE0402.
450412 - ref SDS 43 R44O
450413 -
450414 - [On 140519 0800 during meeting at VA discussed coronary CTA
450415 - with calcium score that tests response to treatment hiking
450416 - 300+ miles per day that creates pharmaphysiological
450417 - conditions of elevated HDL and EPCs which cause rapid
450418 - regression of atherosclerosis to lower CVD risk.
450419 - ref SDS 61 X59G
450421 - ..
450422 - 15. The "Conclusion" says in part...
450423 -
450424 - "...it is recognized that established plaques can rapidly
450425 - stabilize and regress in animals and humans." ref SDS 43 RA7K
450426 -
450427 - [On 140626 1652 letter notifies VA of case studies showing
450428 - failure to perform timely testing causes negative patient
450429 - outcomes. ref SDS 64 MY51 VA reference to patient having
450430 - vessel plaques 5 years ago, begs the question of testing to
450431 - determine currently how much plaque, and level of care
450432 - required, if any, to treat current condition. ref SDS 64
450433 - MZ33 Evidence shows CTA common procedure to evaluate
450434 - current condition post CABG surgery. ref SDS 64 MZ54
450436 - ..
450437 - 16. HDL 67 increased from 30 in 2009, when CABG was performed, may
450438 - be due in part to reliance on orange juice, along with
450439 - increased hiking, following study finding 21% increase in HDL,
450440 - reported on 131125 (see line NV0403. ref SDS 43 K34L
450441 -
450442 - [On 140519 0800 Progress Notes for meeting at VA report
450443 - customer increased intake of orange juice; fails to mention
450444 - correlation with rise in HDL, nor correlation with study.
450445 - ref SDS 60 PB4I
450446 -
450447 -
450448 -
4505 -
SUBJECTS
Default Null Subject Account for Blank Record
4603 -
460401 - ..
460402 - HDL 20 Increase with Orange Juice Aligns Patient History
460403 - Orange Juice Study Aligns Patient History HDL 67 Increase 20%
460404 -
460405 -
460406 - 17. Added orange juice at that time following 131125, about a
460407 - gallon per week. Note 20% increase in HDL between lab on
460408 - 131015 and 140201, and another 10% from 140201 to 140508. [...
460409 - shown in record of VA lab on 140514 0950. ref SDS 58 W25L...].
460410 - This record aligns well with findings in the study.
460411 -
460412 - [On 140519 0800 Progress Notes for meeting at VA report
460413 - customer increased intake of orange juice; fails to mention
460414 - correlation with rise in HDL, nor correlation with study.
460415 - ref SDS 60 PB4I
460416 -
460417 -
460418 -
4605 -
SUBJECTS
Default Null Subject Account for Blank Record
4703 -
470401 - ..
470402 - EPC Add to Labs Assess Potential Regression Atherosclerosis
470403 -
470404 -
470405 - 18. If we redo some of the labs on Monday, might consider adding
470406 - EPC which further indicates potential for regression of plaque,
470407 - along with rising HDL and weight loss. Since, like HDL, EPC
470408 - labs and weight loss respond to exercise [...reported in
470409 - research on 131125 0005, ref SDS 43 6O9M...], we should get
470410 - good numbers that support coronary CTA or IVUS.
470411 -
470412 - [On 140520 0732 letter to VA notifies Doctor Alba about
470413 - adding EPC to follow up lab ordered to test Electrolyte
470414 - panel (Chem Profile). ref SDS 63 4U46
470416 - ..
470417 - [On 140520 0732 at 1028 letter from Doctor Alba requests
470418 - clarification for adding EPC to lab order. ref SDS 63 654J
470419 - Called to explain scope of EPC lab, but encountered poor
470420 - connection using cell phone. ref SDS 63 U63N
470422 - ..
470423 - [On 140520 0732 at 1617 letter to VA submits explanation
470424 - for rationale and justification that warrants testing EPC
470425 - labs in this case, leading to coronary CTA showing
470426 - favorable regression of athersclerotic plaques that can
470427 - justify reducing line of care in order to reduce adverse
470428 - side effects, saving time and money. ref SDS 63 VQ48
470430 - ..
470431 - [On 140703 1938 Doctor Alba reports EPC issue discussed
470432 - among team at VA in detail; determined no justification to
470433 - evaluate EPC toward coronary CTA to assess regression of
470434 - atherosclerosis, ref SDS 65 H167, which VA maintains
470435 - requires treatment, shown in Progress Notes on 140519 0800,
470436 - ref SDS 60 OW76, based solely on history of atherosclerosis
470437 - requiring CABG x4 surgery on 091022, 5 years ago, as
470438 - presented in VA Progress Notes on 140519 0800, ref SDS 60
470439 - OW49, and without knowledge of actual current condition
470440 - resulting from intervening events, e.g., 120% rise from HDL
470441 - 30 to HDL 67, shown in labs on 140514 0950. ref SDS 58 W25L
470442 -
470443 -
470444 -
470445 -
4705 -
SUBJECTS
Default Null Subject Account for Blank Record
4803 -
480401 - ..
480402 - VA Commend Good Care Shown by Excellent Results
480403 -
480404 -
480405 - 19. In sum, recent labs show excellent care at the VA achieving
480406 - favorable results lowering CVD risk for continuing cycles. As
480407 - noted initially, in past years, whenever HDL increased and
480408 - Triglycerides dropped, on the next test the numbers got worse,
480409 - see patient Lipid History Trend Analysis on 140508 (line
480410 - 610726. ref SDS 58 W25L Thanks to skill and persistence of the
480411 - VA medical team, this time the numbers improved.
480413 - ..
480414 - 20. Have a good weekend - see you Monday.
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