THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rod@welchco.com


S U M M A R Y


DIARY: November 26, 2018 10:30 AM Monday; Rod Welch

VA Gina Supartz injections supplement PRP for knees.

1...Summary/Objective
........"Clinical therapy of hyaluronic acid combined with
........platelet-rich plasma for the treatment of knee osteoarthritis"...


..............
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CONTACTS 
0201 - Doctor Gloria Tucker                                                                                                                                               
020101 - Dr. Gloria Tucker                                                                                                                                                
020103 - Medical Offices                                                                                                                                                  

SUBJECTS
Default Null Subject Account for Blank Record                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
0403 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0403 -    ..
0404 - Summary/Objective                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
0405 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
040501 - Follow up ref SDS 49 0000. ref SDS 48 0000.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
040502 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040503 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040504 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040505 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040506 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040507 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040508 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040510 -  ..
0406 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0407 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0408 - Background                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
0409 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
040901 - On 170123 1530 Gina Franco called and left message to pickup Synvisc                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040902 - medication at the Pharmacy, before arriving in Module 2. ref SDS 6                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
040903 - LL52  Went to Pharmacy; they supplied Supartz (Hyalurnate NA 10MG/ML                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040904 - INJ 2.5ML Syringe), and said it is superior to Synvisc. ref SDS 6 LL5N                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
040905 - Gina performed the injection procedure in the right knee only - was                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040906 - fast and painless. ref SDS 6 VG6M                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
040907 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040909 -  ..
040910 - On 180105 1118 Jane called and advised of cancellation, so ordered PRP                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
040911 - treatment in feet and knees by Doctor Gloria Tucker. ref SDS 26 O46F                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
040913 -  ..
040914 - On 180105 1321 letter to Doctor Thuillier in VA Orthopedics notified                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040915 - have been unable to download radiologist report on MRI of both feet                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040916 - performed on 171229. ref SDS 27 O46F  Further explained plan on                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040917 - driving to VAMCSF to get the report from VA Release of Information                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
040918 - (ROI). ref SDS 27 I492  Also planned to schedule meeting with Doctor                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
040919 - Thuillier for review results of MRI studies on feet and knees. 180105                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040920 - 1321, ref SDS 27 I495                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
040922 -  ..
040923 - On 180105 1630 Doctor Tucker performed 3rd PRP injection treatment for                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
040924 - feet and knees again. ref SDS 28 0001                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
040926 -  ..
040927 - On 180108 letter to Doctor Thuillier reported PRP treatment in both                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040928 - feet and both knees on 180105 1630, ref SDS 28 HP5O, and related                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
040929 - research indicating PRP yields measurable increase in minisucs                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
040930 - cartilage over 6 months. ref SDS 28 JX67                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
040932 -  ..
040933 - On 180110 1100 meeting Doctor Thuillier. ref SDS 30 JN9H                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
040935 -  ..
040936 - On 180423 0908 called Jane and scheduled meeting with Doctor Thuillier                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
040937 - on 180425 1145. ref SDS 32 OL9L                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040939 -  ..
040940 - On 180425 1145 meeting Doctor Thuillier review progress recover feet                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040941 - and knee injuries using PRP injection treatments, ref SDS 33 V54H, and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
040942 - order additional care. ref SDS 33 4J6H                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
040944 -  ..
040945 - On 180427 0458 letter to Doctor Thuillier confirm understandings from                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040946 - meeting on 180425. ref SDS 34 V54H                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
040948 -  ..
040949 - On 180516 1015 meeting Doctor Thuillier got name of "smartwool" socks.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
040950 - ref SDS 38 GW5N  The doctor suggested trying Doctor Scholl's Corn                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
040951 - Removers using Salicylic Acid to recover from Tailor's Bunion on left                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040952 - side of left foot, and from calluses on both big toes. ref SDS 38 GW7M                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
040953 - Doctor Thuillier indicated PRP treatments have been strong remedies                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040954 - for metatrsalgia, plantar plate tear, hallux valgus, and Tailor's                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
040955 - Bunion.  He is investigating how VA can pay for the treatments.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040956 - ref SDS 38 GG6J                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040958 -  ..
040959 - On 180521 1045 called Connie in Doctor Tucker's office, and she                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040960 - scheduled PRP treatment on 180620 1530. ref SDS 39 V54H  Connie                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040961 - submitted letter confirming work plan. ref SDS 39 PQ6J  She included                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
040962 - directions to new office location. ref SDS 39 P58O                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
040964 -  ..
040965 - On 180522 2318 submitted letter to Doctor Tucker confirming PRP                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040966 - treatment on 180620 1530, and setting scope for care. ref SDS 40 E476                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
040968 -  ..
040969 - On 180820 1039 scheduled follow up with 5th PRP treatment on 180824                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040970 - 1515. ref SDS 43 E27M                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
040972 -  ..
040973 - On 180824 1515 meeting Doctor Tucker for 5th PRP injection treatment                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040974 - to protect feet and knees. ref SDS 44 0001                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
040976 -  ..
040977 - On 181024 0752 sent letter to Doctor Thuillier, ref SDS 46 FC8M,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
040978 - asking him to order Supartz injections for knees. ref SDS 46 OC44                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
040980 -  ..
040981 - On 181025 0735 received letter from Doctor Thuillier saying he will                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040982 - order Supartz. ref SDS 47 ZY5G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040984 -  ..
040985 - On 181025 0735 at 0801 letter to Jane in Orthopedics Administration,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040986 - asking about coordinating schedule for Supartz injections. ref SDS 47                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
040987 - 7H7S                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
040989 -  ..
040990 - On 181026 1022 Jane called and scheduled Supartz injections in both                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
040991 - knees beginning on 181126 1000. ref SDS 48 V54H                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040993 -  ..
040994 - On 181115 1643 received call from Chris with VA Clinic in Santa Rosa,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040995 - and he confirmed schedule for Gina to give Supartz injection                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
040996 - treatments on 181126, and that the VA will arrange to have medication                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
040997 - delivered to Gina's office, so the patient is not required to received                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
040998 - it from the Pharmacy and deliver to Gina. ref SDS 49 V54H                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
040999 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041000 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041001 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041003 -  ..
0411 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0412 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0413 - Progress                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0414 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
041401 - Visit...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
041402 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041403 -        Santa Rosa VA Community Based Outpatient Clinic                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041404 -        SR Ortho-Franco Phys Asst                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
041405 -        3841 Brickway Boulevard                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
041406 -        Santa Rosa, CA                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041407 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041408 -        415 750 2130 Option 3                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
041410 -         ..
041411 -        Take 101 to Airport Blvd, to Brickway Blvd                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041412 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041414 -  ..
041415 - Chris greeted us in the waiting room, and ushered us into Gina's                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
041416 - office.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
041418 -  ..
041419 - Supartz injections in both knees today, was ordered by Doctor Thuiller                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041420 - at VAMCSF on 181025, ref SDS 47 ZY5G                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
041422 -  ..
041423 - Gina remembered our prior work getting Supartz injection in right knee                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041424 - beginning on 170123 1530. ref SDS 6 C14I                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
041426 -  ..
041427 - Explained getting a 2nd line of care with Supartz in right knee from                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041428 - Joan beginning on 170731 1500. ref SDS 9 0001                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041430 -  ..
041431 - Five (5) days earlier had PRP injections in left knee, performed by                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041432 - Doctor Gloria Tucker at her office in Novato, a few miles South of the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041433 - VA here in Santa Rosa.  This was an experiment to compare                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
041434 - effectiveness of PRP with Supartz, reported on 170726 1600.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
041435 - ref SDS 8 4Y8K                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041437 -  ..
041438 - Gina asked results of this test, and explained she has investigated                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041439 - PRP injections for feet and knees as well.  She hopes to get                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
041440 - assignment for doing injections of PRP, when VA adopts this line of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041441 - care.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041443 -  ..
041444 - While we talked Gina injected Supartz first in the left knee, then                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041445 - the right knee.  Thanked her for excellent skills - did not feel a                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041446 - thing.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041448 -  ..
041449 - Gina has been discussing using PRP at the VA with Doctor Sara Edwards,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041450 - who works in Orthopedics at the VA Medical Center in San Francisco.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041451 - Gina indicated the doctor is a sports medicine specialist at UCSF, and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041452 - strongly supports using PRP to treat repetitive stress injuries like                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041453 - osteoarthritis in knees and metatarsalgia in feet.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041455 -  ..
041456 - Explained work the past year with Doctor Dan Thuillier also in                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
041457 - Orthopedics at VAMCSF, and a professor at UCSF.  He is aware of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041458 - success treating knees and feet in this case with PRP under Doctor                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041459 - Tucker, beginning in July last year, reported on 170726 1600.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
041460 - ref SDS 8 0001                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041462 -  ..
041463 - During the meeting today, explained that PRP injections in feet and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041464 - knees enabled doubling hiking this year to over 3,000 miles, including                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041465 - hiking Half Dome on 180912 0545. ref SDS 45 0001                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041467 -  ..
041468 - Gina was very pleased hearing these favorable results that line up                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041469 - with her research indicating effectiveness of PRP treating repetitive                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041470 - stress injuries to knees.  She reported having worked with Doctor                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041471 - Thuillier on considering PRP at the VA, as well as Doctor Edwards, per                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041472 - above. ref SDS 0 I66I                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041474 -  ..
041475 - Explained meeting with Doctor Gloria Tucker at her office here in                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041476 - Santa Rosa, after getting treatment from Gina today.  The doctor has                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041477 - an article on combining PRP with Supartz (hyaluronic acid) to increase                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041478 - effectiveness of both lines of care.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041480 -  ..
041481 - Gina requested a copy of the article.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041482 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041483 -            [On 181126 1127 meeting Doctor Tucker advised of meeting                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
041484 -            with Gina at VA, and received article on combinging Supartz                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041485 -            with PRP. ref SDS 50 T69K                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
041487 -  ..
041488 - During these discussions, Gina injected both kneew with Supartz.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
041490 -  ..
041491 - She scheduled the next 2 injections on...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
041492 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041493 -        181203 1030                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041494 -        181210 1030                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041496 -  ..
041497 - Both will be performed here at the VA in Santa Rosa.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041498 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041499 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041501 -  ..
0416 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0417 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
0418 - 1952                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
0419 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
041901 - This evening sent letter to Gina with copy to Doctor Thuiller and to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041902 - Doctor Tucker, saying...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
041903 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041904 -    1.  Subject:  Article combine Supartz with PRP                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041905 -        Date:  2018-11-26 20:30                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
041913 -         ..
041914 -    2.  Thanks very much for good care today, providing Supartz                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
041915 -        injections into both knees.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041917 -  ..
041918 - This references meeting with Gina earlier today at VA Clinin in Santa                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041919 - Rosa. ref SDS 0 V54H                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041921 -  ..
041922 - Letter to Gina at VA Clinic in Santa Rosa continues...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
041923 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041924 -    3.  After our meeting, I met with Doctor Gloria Tucker at her                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
041925 -        office in Santa Rosa at 95 Montgomery Street.  She submitted                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041926 -        the article you requested [...reported in another record today                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041927 -        on 181126 1127, ref SDS 50 T66V...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041929 -         ..
041930 -        "Clinical therapy of hyaluronic acid combined with                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
041931 -        platelet-rich plasma for the treatment of knee osteoarthritis"...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
041932 -        -----------------------------------------------------------------                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
041933 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041934 -        ...published by...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
041936 -         ..
041937 -        EXPERIMENTAL AND THERAPEUTIC MEDICINE - SPANDDOS PUBLICATIONS                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041938 -        Published online 2018 Jul 6                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041940 -         ..
041941 -    4.  It is online at...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
041942 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041943 -              https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122407/                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041945 -         ..
041946 -    5.  The abstract summarizes findings, saying...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041947 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041948 -        "PRP and HA combination treatment significantly improved                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041949 -        arthralgia, reduced humoral and cellular immune responses and                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041950 -        promoted angiogenesis, which improved the patients'                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
041951 -        histological parameters compared with PRP or HA treatment                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
041952 -        alone."                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
041954 -         ..
041955 -    6.  If you need a printed copy, I can bring it to the meeting next                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041956 -        Monday, when you will do the 2nd Supartz injections.  Please                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041957 -        let me know.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041959 -         ..
041960 -    7.  Your work with Doctor Sara Edwards in Orthopedics at VAMCSF                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041961 -        considering PRP to compliment Supartz sounds promising.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
041963 -  ..
041964 - References discussion with Gina earlier today, per above. ref SDS 0                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041965 - I66I                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041967 -  ..
041968 - Letter to Gina at VA Clinic in Santa Rosa continues...                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
041969 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041970 -    8.  Have also attached a spreadsheet showing daily hiking the past                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041971 -        8 years, and correlated to increasing HDL nearly 300%, from HDL                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041972 -        30, when I had CABG x4 surgery on 091022, to HDL 83, 2 weeks                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
041973 -        ago on November 12.  You can also see how vitals correlate to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041974 -        hiking.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
041975 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
041976 -              F:\05\00003\SM\CC\BNKG\120216cc\130101cc\hiking_miles_3.xlsx                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
041978 -         ..
041979 -    9.  As we discussed, hiking at this level increases repetitive                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041980 -        stress on feet and knees.  Doctor Dang in Orthopedics at VAMCSF                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041981 -        ordered Supartz in December 2016, for the right knee.  You                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041982 -        started the 3-part injection series on 170123.  Joan later                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041983 -        provided a 2nd series of injections on 170731.  A week prior on                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041984 -        170726, Doctor Gloria Tucker performed PRP injections to treat                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041985 -        metatarsalgia in the feet, since Supartz injections of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
041986 -        hyaluronic acid cannot treat the feet.  She offered to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
041987 -        experiment injecting the left knee to compare effects of PRP,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
041988 -        with Supartz in the right knee.  PRP was later continued in                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041989 -        both knees and feet this year in 2018.  As seen in the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
041990 -        spreadsheet, hiking was only intermittent for 5 years, fighting                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041991 -        feet and knee pain.  This year PRP treatment made hiking 11                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
041992 -        miles per day more consistent.  Amazingly, hiking increased to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041993 -        15 and 20 miles per day, the past 4 weeks.  On 181029, reached                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041994 -        HDL 73, and on 181112, reached HDL 83, with consequent improved                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
041995 -        in vitals.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
041997 -         ..
041998 -   10.  This increased hiking increased damage to feet and knees.  Was                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
041999 -        pleased that Doctor Tucker found the study (cited above)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
042000 -        reporting favorable results combining Supartz with PRP.  Last                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042001 -        month, Doctor Thuillier in Orthopedics at VAMCSF, ordered                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
042002 -        another Supartz treatment, which you started today.  Also,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042003 -        today, Doctor Tucker scheduled another PRP injection treatment                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042004 -        on December 12, after you complete the 3rd Supartz injections                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
042005 -        to both knees.   This will test extending effectiveness of                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
042006 -        injection therapy in the knees, as discussed in the article.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042008 -         ..
042009 -   11.  Accordingly, I am pleased for the opportunity to work with the                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042010 -        VA and Doctor Tucker combining hyaluronic acid with PRP, where                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042011 -        the degree of repetitive stress is high.  The goal would be to                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
042012 -        achieve pain free extended endurance exercise (hiking) for 6                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042013 -        months, as the VA accepts for Supartz alone.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042015 -         ..
042016 -   12.  Thanks again for good care today.  See you December 3, at 1030,                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042017 -        for the 2nd set of Supartz injections, with the 3rd set                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
042018 -        scheduled on December 10, 1030.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
042019 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
042025 -                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
042027 -         ..
042028 -   15.  Attachments:                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
042029 -        hiking_miles_3.xlsx	274 KB                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 
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Distribution. . . . See "CONTACTS"