THE WELCH COMPANY
440 Davis Court #1602
San Francisco, CA 94111-2496
415 781 5700
rodwelch@pacbell.net


S U M M A R Y


DIARY: April 28, 2010 08:00 AM Wednesday; Rod Welch

Millie 1st treatment 3rd cycle Abraxane at Kaiser recover 10th relaspe

1...Summary/Objective


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CONTACTS 

SUBJECTS
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0403 -
0403 -    ..
0404 - Summary/Objective
0405 -
040501 - Follow up ref SDS 44 0000. ref SDS 42 0000.
040502 -
040503 -
040504 -
040505 -
040506 -
040508 -  ..
0406 -
0407 -
0408 - Background
0409 -
040901 - Recent background is listed on 100301 0005. ref SDS 26 625I
040903 -  ..
040904 - On 100302 0830 Doctor Johnson made another examination and confirmed
040905 - diagnosis that Millie's cancer has progressed, and so he ended
040906 - treatment with Navelbine, and ordered treatment to start today with
040907 - Abraxane. ref SDS 27 FC34
040909 -  ..
040910 - On 100302 0830 Doctor Johnson ended Millie's treatment for shingles
040911 - with Acyclovir (Zovirax). ref SDS 27 FU5F  He advised that Abraxane
040912 - causes low blood counts, and low blood counts weaken the immune
040913 - system, making Millie more likely for shingles to recur. ref SDS 27
040914 - IC4N
040916 -  ..
040917 - On 100303 CA 15-3 426 from blood test on 100301 showed another 100
040918 - point rise over the past 2 weeks, while Millie was off treatment for
040919 - the bye-week.
040921 -  ..
040922 - On 100303 Anne confirmed that Abraxane chemotherapy causes low
040923 - blood counts. ref SDS 28 8U95
040925 -  ..
040926 - On 100309 1238 Millie notifies medical team that shingles seems not to
040927 - have recurred despite side effects of Abraxane that lower immunity by
040928 - degrading bone marrow that replenishes blood counts. ref SDS 31 ER95
040929 - Millie further reported that Kaiser's Knowledge Management system was
040930 - of -line and so could not access results of blood test. ref SDS 31
040931 - HL4V
040933 -  ..
040934 - On 100309 1643 Millie notifies medical team that blood counts from the
040935 - lab at Kaiser in the morning of 100309 show significant recovery above
040936 - requirements for getting chemotherapy treatment; since shingles has
040937 - not recurred, Millie is "good-to-go" for treatment on 100310 0730.
040938 - ref SDS 32 2O8W
040940 -  ..
040941 - On 100309 1643 Millie notifies medical team commending Doctor Johnson
040942 - for prescribing only 1 Neupogen treatment to recover from low blood
040943 - counts caused by Abraxane. ref SDS 32 2O9P
040945 -  ..
040946 - On 100310 0730 Millie received the 2nd treatment for the first cycle
040947 - of Abraxane. ref SDS 33 KE4K  Doctor Johnson visited Millie and
040948 - approved treatment based on bood blood counts and no signs of shingles
040949 - recurrence. ref SDS 33 OR3H   The doctor repeated prior notice that
040950 - Kaiser's internal proprietary email system is faster for emergency
040951 - communications. ref SDS 33 OR71
040953 -  ..
040954 - On 100310 1350 Millie notified the medical team that 2nd treatment
040955 - with Abraxane was completed at Kaiser, ref SDS 34 ER95, Millie
040956 - reported that Kaiser's internal proprietary email system has been out
040957 - of service for a week. ref SDS 34 GY4U  Millie further explained that
040958 - faster emergency communications using Kaiser's internal proprietary
040959 - email system is less beneficial than using commercial public domain
040960 - email addresses for doctors at Kaiser that enable timely coordination
040961 - and collaboration among the medical team, which is more advantages to
040962 - survival than improving emergency communications, which rarely occur
040963 - in Millie's case. ref SDS 34 GY6P
040965 -  ..
040966 - On 100317 0730 Millie received the 3rd treatment that completes the
040967 - 1st cycle with Abraxane to recover from the 10th relapse of cancer.
040968 - At this time, Millie is experiencing rising pain from progressing IBC,
040969 - and rising lymphedema, most noticably in the right arm, which has been
040970 - free of disease for 10 years. ref SDS 36 KE4K
040972 -  ..
040973 - On 100330 0830 Doctor Johnson approved Millie to start the 2nd cycle
040974 - of Abraxane to recover from the 10th relapse of cancer. ref SDS 40 KE4K
040976 -  ..
040977 - On 100331 0730 Millie had the 1st treatment for the 2nd cycle of
040978 - Abraxane. ref SDS 40 KE4K
040980 -  ..
040981 - On 100406 0830 Millie had a blood draw at the Kaiser Clinic in
040982 - Martinez. ref SDS 41 AS5H
040984 -  ..
040985 - On 100407 0730 Millie had the 2nd treatment for the 2nd cycle of
040986 - Abraxane. ref SDS 42 KE4K
040988 -  ..
040989 - On 100413 0830 Millie had a blood draw at the Kaiser Clinic in
040990 - Martinez. ref SDS 43 NK7F
040992 -  ..
040993 - On 100407 0730 Millie had the 3rd treatment for the 2nd cycle of
040994 - Abraxane. ref SDS 44 KE4K
040996 -  ..
040997 - On 100426 0830 Millie had a blood draw at the Kaiser Clinic in
040998 - Martinez. ref SDS 45 AS5H
041000 -  ..
041001 - On 100427 0830 Doctor Johnson approved Millie to start the 2nd cycle
041002 - of Abraxane to recover from the 10th relapse of cancer. ref SDS 46
041003 - 0001
041004 -
041005 -
041006 -
041007 -
041009 -  ..
0411 -
0412 -
0413 - Progress
0414 -
041401 - Today starts 1st treatment of 3rd cycle with Abraxane for Millie to
041402 - recover from the 10th relaspe of cancer, diagnosed on 100218 during
041403 - emergency meeting with Doctor Johnson. ref SDS 25 PP5Y
041405 -  ..
041406 - Anne is Millie's nurse today.
041408 -  ..
041409 - Swelling in both arms again requires taking vitals in the leg, rather
041410 - than the right arm, previously reported in Millie's letter to the
041411 - medical team on 100204 1325, ref SDS 22 SB8U, reflecting observations
041412 - by Anne in the Chemotherapy Clinic on 100317 0730, ref SDS 36 QR4X,
041413 - and noted in Millie's letter to the team on 100329 2322. ref SDS 38
041414 - WA8P, and observed by Doctor Johnson during examination at Kaiser on
041415 - 100330 0830. ref SDS 39 C54N
041417 -  ..
041418 - Vitals are still high this morning, with blood pressure ovr 140 80.
041419 - Millie gained 2 pounds to 138.
041421 -  ..
041422 - The lab reported Millie has good blood counts from the test on 100426
041423 - 0830, ref SDS 45 AS5H, and so Millie is okay to start the 1st
041424 - treatment of the 3rd cycle with Abraxane chemotherapy today, reported
041425 - during the meeting at Kaiser on ...
041427 -  ..
041428 - With high blood counts, Millie will need only 1 Neupogen treatment
041429 - this week.
041431 -  ..
041432 - CA 15-3 424 was reported for the cancer marker from the blood test at
041433 - Kaiser on Monday, 100426.  This is another rise, and fairly
041434 - significant compared to patient history shown on 090323 1352.
041435 - ref SDS 3 J13O
041437 -  ..
041438 - There was hope that the marker might decline after a small rise last
041439 - month, reported on 100331 0730. ref SDS 40 GE5F  The cancer marker did
041440 - decline 2 weeks ago, but today breaks the prior pattern with Gemzar
041441 - and Navelbine of continued decline for another few cycles, shown in
041442 - the case study on 090323 1352. ref SDS 3 J13O
041444 -  ..
041445 - This record raises questions about viability of continuing with
041446 - Abraxane, and what treatment should be tried next for Millie.
041448 -  ..
041449 - Doctor Johnson reported in the meeting yesterday at Kaiser that
041450 - Millie's patient profile resists chemotherapy treatments.  He feels
041451 - Millie needs a new strategy using therapy targeted to her cancer,
041452 - rather than chemotherapy, in order to continue looking well and fit,
041453 - as the doctor, also, remarked yesterday on 100427 0830. ref SDS 46
041454 - OJ6I
041456 -         ..
041457 -        [On 100501 1037 Millie notified medical team about Kaiser's new
041458 -        strategy to use targeted treatments instead of chemotherapy,
041459 -        ref SDS 47 F25O, for Millie to recover from 11th relapse of
041460 -        cancer that seems stable to improved on left side, but
041461 -        worsening on the right side. ref SDS 47 U46S  Millie asked to
041462 -        switch treatments based on examination and rising cancer marker
041463 -        CA 15-3 424. ref SDS 47 U44V  She is concerned about cancer
041464 -        cascading out of control without treatment for several weeks,
041465 -        and asks about oral treatments that can be taken while
041466 -        traveling? ref SDS 47 U44Y
041468 -         ..
041469 -        [On 100501 2017 Doctor Rugo reports plans to collaborate
041470 -        with Doctor Johnson at Kaiser on work plan for Millie to
041471 -        recover from 11th relapse of cancer caused by UCSF medical
041472 -        mistakes. ref SDS 48 HH4I
041474 -         ..
041475 -        [On 100503 1945 Kaiser notifies Millie to get remaining 2
041476 -        treatments with Abraxane chemotherapy that seems to be
041477 -        failing, and then after 3 more weeks without treatment,
041478 -        following a trip abroad, the doctor will discuss "next
041479 -        steps." ref SDS 49 YL5N
041481 -         ..
041482 -        [On 100511 0900 cancer marker CA 15-3 520 increased another 100
041483 -        points, seemingly on an accelerating rise, which threatens to
041484 -        cascade out of control. ref SDS 50 L54I
041486 -         ..
041487 -        [On 100512 0730 Millie received 3rd treatment for 3rd cycle
041488 -        of Abraxane. ref SDS 51 KE4K
041489 -
041490 -
041491 -
041492 -
041493 -
0415 -









































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